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Volumn 162, Issue 5, 1999, Pages 2581-2588

Genome-wide linkage analysis of chronic relapsing experimental autoimmune encephalomyelitis in the rat identifies a major susceptibility locus on chromosome 9

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGIC ENCEPHALOMYELITIS; ANIMAL TISSUE; ARTICLE; CHROMOSOME 9; GENE LOCUS; GENETIC ANALYSIS; GENETIC SUSCEPTIBILITY; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0033105381     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (57)

References (57)
  • 1
    • 0029901821 scopus 로고    scopus 로고
    • Genetic epidemiology of multiple sclerosis
    • Ebers, G. C. 1996. Genetic epidemiology of multiple sclerosis. Curr. Opin. Neurol. 9:155.
    • (1996) Curr. Opin. Neurol. , vol.9 , pp. 155
    • Ebers, G.C.1
  • 2
    • 0015733713 scopus 로고
    • Histocompatibility determinants in multiple sclerosis, with special reference to clinical course
    • Jersild, C., T. Fog, G. S. Hansen, M. Thomsen, A. Svejgaard, and B. Dupont. 1973. Histocompatibility determinants in multiple sclerosis, with special reference to clinical course. Lancet 2:1221.
    • (1973) Lancet , vol.2 , pp. 1221
    • Jersild, C.1    Fog, T.2    Hansen, G.S.3    Thomsen, M.4    Svejgaard, A.5    Dupont, B.6
  • 3
    • 0025767289 scopus 로고
    • HLA class II-associated genetic susceptibility in multiple sclerosis: A critical evaluation
    • Olerup, O., and J. Hillert. 1991. HLA class II-associated genetic susceptibility in multiple sclerosis: a critical evaluation. Tissue Antigens 38:1.
    • (1991) Tissue Antigens , vol.38 , pp. 1
    • Olerup, O.1    Hillert, J.2
  • 4
    • 0029121088 scopus 로고
    • A genetic basis for familial aggregation in multiple sclerosis: Canadian Collaborative Study Group
    • Ebers, G. C., A. D. Sadovnick, and N. J. Risch. 1995. A genetic basis for familial aggregation in multiple sclerosis: Canadian Collaborative Study Group. Nature 377:150.
    • (1995) Nature , vol.377 , pp. 150
    • Ebers, G.C.1    Sadovnick, A.D.2    Risch, N.J.3
  • 8
    • 0345632156 scopus 로고
    • Regression analysis of multiple sclerosis data predicts multigenic interaction and minor combined effects of HLA and T-cell receptor genes
    • Phillips, J. T. 1993. Regression analysis of multiple sclerosis data predicts multigenic interaction and minor combined effects of HLA and T-cell receptor genes. Neurology (Suppl.)43:A205.
    • (1993) Neurology (Suppl.) , vol.43
    • Phillips, J.T.1
  • 9
    • 0023243213 scopus 로고
    • α genes of the T cell receptor: A possible implication in genetic susceptibility to multiple sclerosis
    • Martell, M., A. Marcadet, J. Strominger, J. Dausset, and D. Cohen. 1987. α genes of the T cell receptor: a possible implication in genetic susceptibility to multiple sclerosis. C. R. Acad. Sci. III 304:105.
    • (1987) C. R. Acad. Sci. III , vol.304 , pp. 105
    • Martell, M.1    Marcadet, A.2    Strominger, J.3    Dausset, J.4    Cohen, D.5
  • 11
    • 0031911063 scopus 로고    scopus 로고
    • Susceptibility to relapsing-progressive multiple sclerosis is associated with inheritance of genes linked to the variable region of the TCR β locus: Use of affected family-based controls
    • Hockertz, M. K., D. W. Paty, and S. S. Beall. 1998. Susceptibility to relapsing-progressive multiple sclerosis is associated with inheritance of genes linked to the variable region of the TCR β locus: use of affected family-based controls. Am. J. Hum. Genet. 62:373.
    • (1998) Am. J. Hum. Genet. , vol.62 , pp. 373
    • Hockertz, M.K.1    Paty, D.W.2    Beall, S.S.3
  • 14
    • 0025811981 scopus 로고
    • Further localization of a multiple sclerosis susceptibility gene on chromosome 7q using a new T cell receptor β-chain DNA polymorphism
    • Charmley, P., S. S. Beall, P. Concannon, L. Hood, and R. A. Gatti. 1991. Further localization of a multiple sclerosis susceptibility gene on chromosome 7q using a new T cell receptor β-chain DNA polymorphism. J. Neuroimmunol. 32:231.
    • (1991) J. Neuroimmunol. , vol.32 , pp. 231
    • Charmley, P.1    Beall, S.S.2    Concannon, P.3    Hood, L.4    Gatti, R.A.5
  • 15
    • 0024406282 scopus 로고
    • A susceptibility locus for multiple sclerosis is linked to the T cell receptor β chain complex
    • Seboun, E., M. A. Robinson, T. H. Doolittle, T. A. Ciulla, T. J. Kindt, and S. L. Hauser. 1989. A susceptibility locus for multiple sclerosis is linked to the T cell receptor β chain complex. Cell 57:1095.
    • (1989) Cell , vol.57 , pp. 1095
    • Seboun, E.1    Robinson, M.A.2    Doolittle, T.H.3    Ciulla, T.A.4    Kindt, T.J.5    Hauser, S.L.6
  • 16
    • 0026670087 scopus 로고
    • Genetic susceptibility to multiple sclerosis linked to myelin basic protein gene
    • Tienari, P. J., J. Wikstrom, A. Sajantila, J. Palo, and L. Peltonen. 1992. Genetic susceptibility to multiple sclerosis linked to myelin basic protein gene. Lancet 340:987.
    • (1992) Lancet , vol.340 , pp. 987
    • Tienari, P.J.1    Wikstrom, J.2    Sajantila, A.3    Palo, J.4    Peltonen, L.5
  • 17
    • 0023124638 scopus 로고
    • Susceptibility to multiple sclerosis associated with an immunoglobulin γ3 restriction fragment length polymorphism
    • Gaiser, C. N., M. J. Johnson, G. de Lange, L. Rassenti, L. L. Cavalli-Sforza, and L. Steinman. 1987. Susceptibility to multiple sclerosis associated with an immunoglobulin γ3 restriction fragment length polymorphism. J. Clin. Invest. 79:309.
    • (1987) J. Clin. Invest. , vol.79 , pp. 309
    • Gaiser, C.N.1    Johnson, M.J.2    De Lange, G.3    Rassenti, L.4    Cavalli-Sforza, L.L.5    Steinman, L.6
  • 18
    • 0025762748 scopus 로고
    • Susceptibility to multiple sclerosis is associated with the proximal immunoglobulin heavy chain variable region
    • Walter, M. A., W. T. Gibson, G. C. Ebers, and D. W. Cox. 1991. Susceptibility to multiple sclerosis is associated with the proximal immunoglobulin heavy chain variable region. J. Clin. Invest. 87:1266.
    • (1991) J. Clin. Invest. , vol.87 , pp. 1266
    • Walter, M.A.1    Gibson, W.T.2    Ebers, G.C.3    Cox, D.W.4
  • 20
    • 0026774406 scopus 로고
    • T cell receptor α chain polymorphisms in multiple sclerosis
    • Hashimoto, L. L., T. W. Mak, and G. C. Ebers. 1992. T cell receptor α chain polymorphisms in multiple sclerosis. J. Neuroimmunol. 40:41.
    • (1992) J. Neuroimmunol. , vol.40 , pp. 41
    • Hashimoto, L.L.1    Mak, T.W.2    Ebers, G.C.3
  • 21
    • 0026564544 scopus 로고
    • T-cell receptor α chain germline gene polymorphisms in multiple sclerosis
    • Hillert, J., C. Leng, and O. Olerup. 1992. T-cell receptor α chain germline gene polymorphisms in multiple sclerosis. Neurology 42:80.
    • (1992) Neurology , vol.42 , pp. 80
    • Hillert, J.1    Leng, C.2    Olerup, O.3
  • 22
    • 0028147010 scopus 로고
    • The myelin basic protein gene is not a major susceptibility locus for multiple sclerosis in Italian patients
    • Eoli, M., M. Pandolfo, C. Milanese, P. Gasparini, A. Salmaggi, and M. Zeviani. 1994. The myelin basic protein gene is not a major susceptibility locus for multiple sclerosis in Italian patients. J. Neurol. 241:615.
    • (1994) J. Neurol. , vol.241 , pp. 615
    • Eoli, M.1    Pandolfo, M.2    Milanese, C.3    Gasparini, P.4    Salmaggi, A.5    Zeviani, M.6
  • 23
    • 0025329622 scopus 로고
    • The germline repertoire of T-cell receptor β chain genes in patients with relapsing/remitting multiple sclerosis or optic neuritis
    • Fugger, L., M. Sandberg-Wollheim, N. Morling, L. P. Ryder, and A. Svejgaard. 1990. The germline repertoire of T-cell receptor β chain genes in patients with relapsing/remitting multiple sclerosis or optic neuritis. Immunogenetics 31:278.
    • (1990) Immunogenetics , vol.31 , pp. 278
    • Fugger, L.1    Sandberg-Wollheim, M.2    Morling, N.3    Ryder, L.P.4    Svejgaard, A.5
  • 24
    • 0025907869 scopus 로고
    • No association with germline T cell receptor β-chain gene alleles or haplotypes in Swedish patients with multiple sclerosis
    • Hillert, J., C. Leng, and O. Olerup. 1991. No association with germline T cell receptor β-chain gene alleles or haplotypes in Swedish patients with multiple sclerosis. J. Neuroimmunol. 32:141.
    • (1991) J. Neuroimmunol. , vol.32 , pp. 141
    • Hillert, J.1    Leng, C.2    Olerup, O.3
  • 26
    • 0027263247 scopus 로고
    • Genetic susceptibility in familial multiple sclerosis not linked to the myelin basic protein gene
    • Rose, J., S. Gerken, S. Lynch, P. Pisani, T. Varvil, B. Otterud, and M. Leppert. 1993. Genetic susceptibility in familial multiple sclerosis not linked to the myelin basic protein gene. Lancet 341:1179.
    • (1993) Lancet , vol.341 , pp. 1179
    • Rose, J.1    Gerken, S.2    Lynch, S.3    Pisani, P.4    Varvil, T.5    Otterud, B.6    Leppert, M.7
  • 31
    • 0028877463 scopus 로고
    • Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
    • Lander, E., and L. Kruglyak. 1995. Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat. Genet. 11:241.
    • (1995) Nat. Genet. , vol.11 , pp. 241
    • Lander, E.1    Kruglyak, L.2
  • 32
    • 0028952250 scopus 로고
    • High-resolution genetic mapping of complex traits
    • Kruglyak, L., and E. S. Lander. 1995. High-resolution genetic mapping of complex traits. Am. J. Hum. Genet. 56:1212.
    • (1995) Am. J. Hum. Genet. , vol.56 , pp. 1212
    • Kruglyak, L.1    Lander, E.S.2
  • 33
    • 0029011132 scopus 로고
    • Identification of murine loci associated with susceptibility to chronic experimental autoimmune encephalomyelitis
    • Sundvall, M., J. Jirholt, H. T. Yang, L. Jansson, A. Engstrom, U. Pettersson, and R. Holmdahl. 1995. Identification of murine loci associated with susceptibility to chronic experimental autoimmune encephalomyelitis. Nat. Genet. 10:313.
    • (1995) Nat. Genet. , vol.10 , pp. 313
    • Sundvall, M.1    Jirholt, J.2    Yang, H.T.3    Jansson, L.4    Engstrom, A.5    Pettersson, U.6    Holmdahl, R.7
  • 34
    • 0029120178 scopus 로고
    • Genetic analysis of experimental allergic encephalomyelitis in mice
    • Baker, D., O. A. Rosenwasser, J. K. O'Neill, and J. L. Turk. 1995. Genetic analysis of experimental allergic encephalomyelitis in mice. J. Immunol. 155: 4046.
    • (1995) J. Immunol. , vol.155 , pp. 4046
    • Baker, D.1    Rosenwasser, O.A.2    O'Neill, J.K.3    Turk, J.L.4
  • 35
    • 0029785817 scopus 로고    scopus 로고
    • Inheritance of susceptibility to experimental autoimmune encephalomyelitis
    • Encinas, J. A., H. L. Weiner, and V. K. Kuchroo. 1996. Inheritance of susceptibility to experimental autoimmune encephalomyelitis. J. Neurosci. Res. 45:655.
    • (1996) J. Neurosci. Res. , vol.45 , pp. 655
    • Encinas, J.A.1    Weiner, H.L.2    Kuchroo, V.K.3
  • 38
    • 0029560231 scopus 로고
    • Protracted, relapsing, and demyelinating experimental autoimmune encephalomyelitis in DA rats immunized with syngeneic spinal cord and incomplete Freund's adjuvant
    • Lorentzen, J. C., S. Issazadeh, M. Storch, M. I. Mustafa, H. Lassman, C. Linington, L. Klareskog, and T. Olsson. 1995. Protracted, relapsing, and demyelinating experimental autoimmune encephalomyelitis in DA rats immunized with syngeneic spinal cord and incomplete Freund's adjuvant. J. Neuroimmunol. 63:193.
    • (1995) J. Neuroimmunol. , vol.63 , pp. 193
    • Lorentzen, J.C.1    Issazadeh, S.2    Storch, M.3    Mustafa, M.I.4    Lassman, H.5    Linington, C.6    Klareskog, L.7    Olsson, T.8
  • 39
    • 0030248470 scopus 로고    scopus 로고
    • Cytokines in relapsing experimental autoimmune encephalomyelitis in DA rats: Persistent mRNA expression of proinflammatory cytokines and absent expression of interleukin-10 and transforming growth factor-β
    • Issazadeh, S., J. C. Lorentzen, M. I. Mustafa, B. Hojeberg, A. Mussener, and T. Olsson. 1996. Cytokines in relapsing experimental autoimmune encephalomyelitis in DA rats: persistent mRNA expression of proinflammatory cytokines and absent expression of interleukin-10 and transforming growth factor-β. J. Neuroimmunol. 69:103.
    • (1996) J. Neuroimmunol. , vol.69 , pp. 103
    • Issazadeh, S.1    Lorentzen, J.C.2    Mustafa, M.I.3    Hojeberg, B.4    Mussener, A.5    Olsson, T.6
  • 40
    • 0031437138 scopus 로고    scopus 로고
    • Genetic analysis of inflammation, cytokine mRNA expression, and disease course of relapsing experimental autoimmune encephalomyelitis in DA rats
    • Lorentzen, J. C., M. Andersson, S. Issazadeh, I. Dahlman, H. Luthman, R. Weissert, and T. Olsson. 1997. Genetic analysis of inflammation, cytokine mRNA expression, and disease course of relapsing experimental autoimmune encephalomyelitis in DA rats. J. Neuroimmunol. 80:31.
    • (1997) J. Neuroimmunol. , vol.80 , pp. 31
    • Lorentzen, J.C.1    Andersson, M.2    Issazadeh, S.3    Dahlman, I.4    Luthman, H.5    Weissert, R.6    Olsson, T.7
  • 41
    • 0023186982 scopus 로고
    • Experimental allergic encephalomyelitis in the absence of a classical delayed-type hypersensitivity reaction: Severe paralytic disease correlates with the presence of interleukin 2 receptor-positive cells infiltrating the central nervous system
    • Sedgwick, J., S. Brostoff, and D. Mason. 1987. Experimental allergic encephalomyelitis in the absence of a classical delayed-type hypersensitivity reaction: severe paralytic disease correlates with the presence of interleukin 2 receptor-positive cells infiltrating the central nervous system. J. Exp. Med. 165:1058.
    • (1987) J. Exp. Med. , vol.165 , pp. 1058
    • Sedgwick, J.1    Brostoff, S.2    Mason, D.3
  • 42
    • 0018406350 scopus 로고
    • Identification of la glycoproteins in rat thymus and purification from rat spleen
    • McMaster, W. R., and A. F. Williams. 1979. Identification of la glycoproteins in rat thymus and purification from rat spleen. Eur. J. Immunol. 9:426.
    • (1979) Eur. J. Immunol. , vol.9 , pp. 426
    • McMaster, W.R.1    Williams, A.F.2
  • 43
    • 0022374771 scopus 로고
    • A rapid and efficient immunization protocol for production of monoclonal antibodies reactive with autoantigens
    • Holmdahl, R., T. Moran, and M. Andersson. 1985. A rapid and efficient immunization protocol for production of monoclonal antibodies reactive with autoantigens. J. Immunol. Methods 83:379.
    • (1985) J. Immunol. Methods , vol.83 , pp. 379
    • Holmdahl, R.1    Moran, T.2    Andersson, M.3
  • 44
    • 0030008498 scopus 로고    scopus 로고
    • Memantine abrogates neurological deficits, but not CNS inflammation, in Lewis rat experimental autoimmune encephalomyelitis
    • Wallstrom, E., P. Diener, A. Ljungdahl, M. Khademi, C. G. Nilsson, and T. Olsson. 1996. Memantine abrogates neurological deficits, but not CNS inflammation, in Lewis rat experimental autoimmune encephalomyelitis. J. Neurol. Sci. 137:89.
    • (1996) J. Neurol. Sci. , vol.137 , pp. 89
    • Wallstrom, E.1    Diener, P.2    Ljungdahl, A.3    Khademi, M.4    Nilsson, C.G.5    Olsson, T.6
  • 45
    • 0028956025 scopus 로고
    • Interferon γ, interleukin 4, and transforming growth factor β in experimental autoimmune encephalomyelitis in Lewis rats: Dynamics of cellular mRNA expression in the central nervous system and lymphoid cells
    • Issazadeh, S., M. Mustafa, A. Ljungdahl, B. Hojeberg, A. Dagerlind, R. Elde, and T. Olsson. 1995. Interferon γ, interleukin 4, and transforming growth factor β in experimental autoimmune encephalomyelitis in Lewis rats: dynamics of cellular mRNA expression in the central nervous system and lymphoid cells. J. Neurosci. Res. 40:579.
    • (1995) J. Neurosci. Res. , vol.40 , pp. 579
    • Issazadeh, S.1    Mustafa, M.2    Ljungdahl, A.3    Hojeberg, B.4    Dagerlind, A.5    Elde, R.6    Olsson, T.7
  • 49
    • 0023426747 scopus 로고
    • MAPMAKER: An interactive computer package for constructing primary genetic linkage maps of experimental and natural populations
    • Lander, E. S., P. Green, J. Abrahamson, A. Barlow, M. J. Daly, S. E. Lincoln, and L. Newburg. 1987. MAPMAKER: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations. Genomics 1:174.
    • (1987) Genomics , vol.1 , pp. 174
    • Lander, E.S.1    Green, P.2    Abrahamson, J.3    Barlow, A.4    Daly, M.J.5    Lincoln, S.E.6    Newburg, L.7
  • 51
    • 0026086019 scopus 로고
    • T cell immunity and interferon-γ secretion during experimental allergic encephalomyelitis in Lewis rats
    • Mustafa, M. I., P. Diener, B. Hojeberg, P. Van der Meide, and T. Olsson. 1991. T cell immunity and interferon-γ secretion during experimental allergic encephalomyelitis in Lewis rats. J. Neuroimmunol. 31:165.
    • (1991) J. Neuroimmunol. , vol.31 , pp. 165
    • Mustafa, M.I.1    Diener, P.2    Hojeberg, B.3    Van Der Meide, P.4    Olsson, T.5
  • 52
    • 0030135421 scopus 로고    scopus 로고
    • Targeted CNS expression of interferon-γ in transgenic mice leads to hypomyelination, reactive gliosis, and abnormal cerebellar development
    • Corbin, J. G., D. Kelly, E. M. Rath, K. D. Baerwald, K. Suzuki, and B. Popko. 1996. Targeted CNS expression of interferon-γ in transgenic mice leads to hypomyelination, reactive gliosis, and abnormal cerebellar development. Mol. Cell. Neurosci. 7:354.
    • (1996) Mol. Cell. Neurosci. , vol.7 , pp. 354
    • Corbin, J.G.1    Kelly, D.2    Rath, E.M.3    Baerwald, K.D.4    Suzuki, K.5    Popko, B.6
  • 54
    • 0032536447 scopus 로고    scopus 로고
    • An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease
    • Segal, B. M., B. K. Dwyer, and E. M. Shevach. 1998. An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease. J. Exp. Med. 187:537.
    • (1998) J. Exp. Med. , vol.187 , pp. 537
    • Segal, B.M.1    Dwyer, B.K.2    Shevach, E.M.3


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