메뉴 건너뛰기




Volumn 11, Issue 2, 2014, Pages 156-164

Regulator of calcineurin 1 gene transcription is regulated by nuclear factor-kappaB

Author keywords

Gene transcription; Negative feed back loop; Nuclear factor kappaB; RCAN

Indexed keywords

CALCINEURIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR NFAT; MUSCLE PROTEIN; RCAN1 PROTEIN, HUMAN; SIGNAL PEPTIDE;

EID: 84897422685     PISSN: 15672050     EISSN: 18755828     Source Type: Journal    
DOI: 10.2174/1567205010666131212114907     Document Type: Article
Times cited : (21)

References (43)
  • 1
    • 0028856422 scopus 로고
    • A new human gene from the Down syndrome critical region encodes a proline-rich protein highly expressed in fetal brain and heart
    • Fuentes JJ, Pritchard MA, Planas AM, Bosch A, Ferrer I, Estivill X. A new human gene from the Down syndrome critical region encodes a proline-rich protein highly expressed in fetal brain and heart. Hum Mol Genet 4(10): 1935-44 (1995).
    • (1995) Hum Mol Genet , vol.4 , Issue.10 , pp. 1935-1944
    • Fuentes, J.J.1    Pritchard, M.A.2    Planas, A.M.3    Bosch, A.4    Ferrer, I.5    Estivill, X.6
  • 2
    • 67649506317 scopus 로고    scopus 로고
    • Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1
    • Baek KH, Zaslavsky A, Lynch RC, Britt C, Okada Y, Siarey RJ, et al. Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1. Nature 459(7250): 1126-30 (2009).
    • (2009) Nature , vol.459 , Issue.7250 , pp. 1126-1130
    • Baek, K.H.1    Zaslavsky, A.2    Lynch, R.C.3    Britt, C.4    Okada, Y.5    Siarey, R.J.6
  • 3
    • 33646171446 scopus 로고    scopus 로고
    • NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21
    • Arron JR, Winslow MM, Polleri A, Chang CP, Wu H, Gao X, et al. NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21. Nature 441(7093): 595-600 (2006).
    • (2006) Nature , vol.441 , Issue.7093 , pp. 595-600
    • Arron, J.R.1    Winslow, M.M.2    Polleri, A.3    Chang, C.P.4    Wu, H.5    Gao, X.6
  • 4
    • 24944484976 scopus 로고    scopus 로고
    • Identification of a peptide fragment of DSCR1 that competitively inhibits calcineurin activity in vitro and in vivo
    • Chan B, Greenan G, McKeon F, Ellenberger T. Identification of a peptide fragment of DSCR1 that competitively inhibits calcineurin activity in vitro and in vivo. Proc Natl Acad Sci USA 102(37): 13075-80 (2005).
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.37 , pp. 13075-13080
    • Chan, B.1    Greenan, G.2    McKeon, F.3    Ellenberger, T.4
  • 5
    • 0035853110 scopus 로고    scopus 로고
    • Myocyte-enriched calcineurin-interacting protein, MCIP1, inhibits cardiac hypertrophy in vivo
    • Rothermel BA, McKinsey TA, Vega RB, Nicol RL, Mammen P, Yang J, et al. Myocyte-enriched calcineurin-interacting protein, MCIP1, inhibits cardiac hypertrophy in vivo. Proc Natl Acad Sci USA 98(6): 3328-33 (2001).
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.6 , pp. 3328-3333
    • Rothermel, B.A.1    McKinsey, T.A.2    Vega, R.B.3    Nicol, R.L.4    Mammen, P.5    Yang, J.6
  • 6
    • 0034234543 scopus 로고    scopus 로고
    • DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathways
    • Fuentes JJ, Genesca L, Kingsbury TJ, Cunningham KW, Perez-Riba M, Estivill X, et al. DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathways. Hum Mol Genet 9(11): 1681-90 (2000).
    • (2000) Hum Mol Genet , vol.9 , Issue.11 , pp. 1681-1690
    • Fuentes, J.J.1    Genesca, L.2    Kingsbury, T.J.3    Cunningham, K.W.4    Perez-Riba, M.5    Estivill, X.6
  • 7
    • 0034708825 scopus 로고    scopus 로고
    • A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling
    • Rothermel B, Vega RB, Yang J, Wu H, Bassel-Duby R, Williams RS. A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling. J Biol Chem 275(12): 8719-25 (2000).
    • (2000) J Biol Chem , vol.275 , Issue.12 , pp. 8719-8725
    • Rothermel, B.1    Vega, R.B.2    Yang, J.3    Wu, H.4    Bassel-Duby, R.5    Williams, R.S.6
  • 8
    • 2442420976 scopus 로고    scopus 로고
    • MCIP1 overexpression suppresses left ventricular remodeling and sustains cardiac function after myocardial infarction
    • van Rooij E, Doevendans PA, Crijns HJ, Heeneman S, Lips DJ, van Bilsen M, et al. MCIP1 overexpression suppresses left ventricular remodeling and sustains cardiac function after myocardial infarction. Circ Res 94(3): e18-26 (2004).
    • (2004) Circ Res , vol.94 , Issue.3
    • van Rooij, E.1    Doevendans, P.A.2    Crijns, H.J.3    Heeneman, S.4    Lips, D.J.5    van Bilsen, M.6
  • 9
    • 24344448213 scopus 로고    scopus 로고
    • KiSS-1/G protein-coupled receptor 54 metastasis suppressor pathway increases myocyte-enriched calcineurin interacting protein 1 expression and chronically inhibits calcineurin activity
    • Stathatos N, Bourdeau I, Espinosa AV, Saji M, Vasko VV, Burman KD, et al. KiSS-1/G protein-coupled receptor 54 metastasis suppressor pathway increases myocyte-enriched calcineurin interacting protein 1 expression and chronically inhibits calcineurin activity. J Clin Endocrinol Metab 90(9): 5432-40 (2005).
    • (2005) J Clin Endocrinol Metab , vol.90 , Issue.9 , pp. 5432-5440
    • Stathatos, N.1    Bourdeau, I.2    Espinosa, A.V.3    Saji, M.4    Vasko, V.V.5    Burman, K.D.6
  • 10
    • 9644262448 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-and thrombin-induced termination factor, Down syndrome critical region-1, attenuates endothelial cell proliferation and angiogenesis
    • Minami T, Horiuchi K, Miura M, Abid MR, Takabe W, Noguchi N, et al. Vascular endothelial growth factor-and thrombin-induced termination factor, Down syndrome critical region-1, attenuates endothelial cell proliferation and angiogenesis. J Biol Chem 279(48): 50537-54 (2004).
    • (2004) J Biol Chem , vol.279 , Issue.48 , pp. 50537-50554
    • Minami, T.1    Horiuchi, K.2    Miura, M.3    Abid, M.R.4    Takabe, W.5    Noguchi, N.6
  • 11
    • 33646357770 scopus 로고    scopus 로고
    • Protein kinase-mediated regulation of calcineurin through the phosphorylation of modulatory calcineurin-interacting protein 1
    • Abbasi S, Lee JD, Su B, Chen X, Alcon JL, Yang J, et al. Protein kinase-mediated regulation of calcineurin through the phosphorylation of modulatory calcineurin-interacting protein 1. J Biol Chem 281(12): 7717-26 (2006).
    • (2006) J Biol Chem , vol.281 , Issue.12 , pp. 7717-7726
    • Abbasi, S.1    Lee, J.D.2    Su, B.3    Chen, X.4    Alcon, J.L.5    Yang, J.6
  • 12
    • 27744595555 scopus 로고    scopus 로고
    • The essential role of MEKK3 signaling in angiotensin II-induced calcineurin/nuclear factor of activated T-cells activation
    • Abbasi S, Su B, Kellems RE, Yang J, Xia Y. The essential role of MEKK3 signaling in angiotensin II-induced calcineurin/nuclear factor of activated T-cells activation. J Biol Chem 280(44): 36737-46 (2005).
    • (2005) J Biol Chem , vol.280 , Issue.44 , pp. 36737-36746
    • Abbasi, S.1    Su, B.2    Kellems, R.E.3    Yang, J.4    Xia, Y.5
  • 14
    • 0037119382 scopus 로고    scopus 로고
    • Multiple domains of MCIP1 contribute to inhibition of calcineurin activity
    • Vega RB, Yang J, Rothermel BA, Bassel-Duby R, Williams RS. Multiple domains of MCIP1 contribute to inhibition of calcineurin activity. J Biol Chem 277(33): 30401-7 (2002).
    • (2002) J Biol Chem , vol.277 , Issue.33 , pp. 30401-30407
    • Vega, R.B.1    Yang, J.2    Rothermel, B.A.3    Bassel-Duby, R.4    Williams, R.S.5
  • 15
    • 0041761256 scopus 로고    scopus 로고
    • Phosphorylation of calcipressin 1 increases its ability to inhibit calcineurin and decreases calcipressin half-life
    • Genesca L, Aubareda A, Fuentes JJ, Estivill X, De La Luna S, Perez-Riba M. Phosphorylation of calcipressin 1 increases its ability to inhibit calcineurin and decreases calcipressin half-life. Biochem J 374(Pt 2): 567-75 (2003).
    • (2003) Biochem J , vol.374 , Issue.Pt 2 , pp. 567-575
    • Genesca, L.1    Aubareda, A.2    Fuentes, J.J.3    Estivill, X.4    De La Luna, S.5    Perez-Riba, M.6
  • 17
    • 41249098372 scopus 로고    scopus 로고
    • NF-kappaBinducing kinase phosphorylates and blocks the degradation of Down syndrome candidate region 1
    • Lee EJ, Seo SR, Um JW, Park J, Oh Y, Chung KC. NF-kappaBinducing kinase phosphorylates and blocks the degradation of Down syndrome candidate region 1. J Biol Chem 283(6): 3392-400 (2008).
    • (2008) J Biol Chem , vol.283 , Issue.6 , pp. 3392-3400
    • Lee, E.J.1    Seo, S.R.2    Um, J.W.3    Park, J.4    Oh, Y.5    Chung, K.C.6
  • 18
    • 59649116320 scopus 로고    scopus 로고
    • Interaction between TAK1-TAB1-TAB2 and RCAN1-calcineurin defines a signalling nodal control point
    • Liu Q, Busby JC, Molkentin JD. Interaction between TAK1-TAB1-TAB2 and RCAN1-calcineurin defines a signalling nodal control point. Nat Cell Biol 11(2): 154-61 (2009).
    • (2009) Nat Cell Biol , vol.11 , Issue.2 , pp. 154-161
    • Liu, Q.1    Busby, J.C.2    Molkentin, J.D.3
  • 19
    • 70349666552 scopus 로고    scopus 로고
    • Degradation of regulator of calcineurin 1 (RCAN1) is mediated by both chaperone-mediated autophagy and ubiquitin proteasome pathways
    • Liu H, Wang P, Song W, Sun X. Degradation of regulator of calcineurin 1 (RCAN1) is mediated by both chaperone-mediated autophagy and ubiquitin proteasome pathways. FASEB J 23(10): 3383-92 (2009).
    • (2009) FASEB J , vol.23 , Issue.10 , pp. 3383-3392
    • Liu, H.1    Wang, P.2    Song, W.3    Sun, X.4
  • 20
    • 79953168726 scopus 로고    scopus 로고
    • Regulator of calcineurin 1 (RCAN1) facilitates neuronal apoptosis through caspase-3 activation
    • Sun X, Wu Y, Chen B, Zhang Z, Zhou W, Tong Y, et al. Regulator of calcineurin 1 (RCAN1) facilitates neuronal apoptosis through caspase-3 activation. J Biol Chem 286(11): 9049-62 (2011).
    • (2011) J Biol Chem , vol.286 , Issue.11 , pp. 9049-9062
    • Sun, X.1    Wu, Y.2    Chen, B.3    Zhang, Z.4    Zhou, W.5    Tong, Y.6
  • 21
    • 0032508414 scopus 로고    scopus 로고
    • NF-kappaB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
    • Wang CY, Mayo MW, Korneluk RG, Goeddel DV, Baldwin AS, Jr. NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science 281(5383): 1680-3 (1998).
    • (1998) Science , vol.281 , Issue.5383 , pp. 1680-1683
    • Wang, C.Y.1    Mayo, M.W.2    Korneluk, R.G.3    Goeddel, D.V.4    Baldwin Jr., A.S.5
  • 22
    • 37549004392 scopus 로고    scopus 로고
    • Nuclear factor-kappaB activation: From bench to bedside
    • Sethi G, Sung B, Aggarwal BB. Nuclear factor-kappaB activation: from bench to bedside. Exp Biol Med (Maywood) 233(1): 21-31(2008).
    • (2008) Exp Biol Med (Maywood) , vol.233 , Issue.1 , pp. 21-31
    • Sethi, G.1    Sung, B.2    Aggarwal, B.B.3
  • 23
    • 0029874138 scopus 로고    scopus 로고
    • The NF-kappa B and I kappa B proteins: New discoveries and insights
    • Baldwin AS, Jr. The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu Rev Immunol 14: 649-83.(1996).
    • (1996) Annu Rev Immunol , vol.14 , pp. 649-683
    • Baldwin Jr., A.S.1
  • 24
    • 0023724778 scopus 로고
    • I kappa B: A specific inhibitor of the NF-kappa B transcription factor
    • Baeuerle PA, Baltimore D. I kappa B: a specific inhibitor of the NF-kappa B transcription factor. Science 242(4878): 540-6 (1988).
    • (1988) Science , vol.242 , Issue.4878 , pp. 540-546
    • Baeuerle, P.A.1    Baltimore, D.2
  • 25
    • 0028174061 scopus 로고
    • Function and activation of NF-kappa B in the immune system
    • Baeuerle PA, Henkel T. Function and activation of NF-kappa B in the immune system. Annu Rev Immunol 12: 141-79 (1994).
    • (1994) Annu Rev Immunol , vol.12 , pp. 141-179
    • Baeuerle, P.A.1    Henkel, T.2
  • 26
    • 0029874138 scopus 로고    scopus 로고
    • review-The NF-kappa B and I kappa B proteins: New discoveries and insights
    • Baldwin AS, Jr. review-The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu Rev Immunol 14: 649-83 (1996).
    • (1996) Annu Rev Immunol , vol.14 , pp. 649-683
    • Baldwin Jr., A.S.1
  • 27
    • 0028970734 scopus 로고
    • Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitinproteasome pathway
    • Alkalay I, Yaron A, Hatzubai A, Orian A, Ciechanover A, Ben-Neriah Y. Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitinproteasome pathway. Proc Natl Acad Sci USA 92(23): 10599-603 (1995).
    • (1995) Proc Natl Acad Sci USA , vol.92 , Issue.23 , pp. 10599-10603
    • Alkalay, I.1    Yaron, A.2    Hatzubai, A.3    Orian, A.4    Ciechanover, A.5    Ben-Neriah, Y.6
  • 28
    • 0031572313 scopus 로고    scopus 로고
    • Genomic organization, alternative splicing, and expression patterns of the DSCR1 (Down syndrome candidate region 1) gene
    • Fuentes JJ, Pritchard MA, Estivill X. Genomic organization, alternative splicing, and expression patterns of the DSCR1 (Down syndrome candidate region 1) gene. Genomics 44(3): 358-61 (1997).
    • (1997) Genomics , vol.44 , Issue.3 , pp. 358-361
    • Fuentes, J.J.1    Pritchard, M.A.2    Estivill, X.3
  • 29
    • 0034624137 scopus 로고    scopus 로고
    • Independent signals control expression of the calcineurin inhibitory proteins MCIP1 and MCIP2 in striated muscles
    • Yang J, Rothermel B, Vega RB, Frey N, McKinsey TA, Olson EN, et al. Independent signals control expression of the calcineurin inhibitory proteins MCIP1 and MCIP2 in striated muscles. Circ Res 87(12): E61-8 (2000).
    • (2000) Circ Res , vol.87 , Issue.12
    • Yang, J.1    Rothermel, B.2    Vega, R.B.3    Frey, N.4    McKinsey, T.A.5    Olson, E.N.6
  • 30
    • 33845505233 scopus 로고    scopus 로고
    • Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expression
    • Sun X, He G, Qing H, Zhou W, Dobie F, Cai F, et al. Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expression. Proc Natl Acad Sci USA 103(49): 18727-32 (2006).
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.49 , pp. 18727-18732
    • Sun, X.1    He, G.2    Qing, H.3    Zhou, W.4    Dobie, F.5    Cai, F.6
  • 31
    • 20944444583 scopus 로고    scopus 로고
    • Distinct transcriptional regulation and function of the human BACE2 and BACE1 genes
    • Sun X, Wang Y, Qing H, Christensen MA, Liu Y, Zhou W, et al. Distinct transcriptional regulation and function of the human BACE2 and BACE1 genes. FASEB J 19(7): 739-49 (2005).
    • (2005) FASEB J , vol.19 , Issue.7 , pp. 739-749
    • Sun, X.1    Wang, Y.2    Qing, H.3    Christensen, M.A.4    Liu, Y.5    Zhou, W.6
  • 32
    • 79953188323 scopus 로고    scopus 로고
    • REST regulates DYRK1A transcription in a negative feedback loop
    • Lu M, Zheng L, Han B, Wang L, Wang P, Liu H, et al. REST regulates DYRK1A transcription in a negative feedback loop. J Biol Chem 286(12): 10755-63 (2011).
    • (2011) J Biol Chem , vol.286 , Issue.12 , pp. 10755-10763
    • Lu, M.1    Zheng, L.2    Han, B.3    Wang, L.4    Wang, P.5    Liu, H.6
  • 33
    • 23844525083 scopus 로고    scopus 로고
    • Depolarization of neural cells induces transcription of the Down syndrome critical region 1 isoform 4 via a calcineurin/nuclear factor of activated T cells-dependent pathway
    • Cano E, Canellada A, Minami T, Iglesias T, Redondo JM. Depolarization of neural cells induces transcription of the Down syndrome critical region 1 isoform 4 via a calcineurin/nuclear factor of activated T cells-dependent pathway. J Biol Chem 280(33): 29435-43 (2005).
    • (2005) J Biol Chem , vol.280 , Issue.33 , pp. 29435-29443
    • Cano, E.1    Canellada, A.2    Minami, T.3    Iglesias, T.4    Redondo, J.M.5
  • 34
    • 79955770845 scopus 로고    scopus 로고
    • Reconsolidation or extinction: Transcription factor switch in the determination of memory course after retrieval
    • de la Fuente V, Freudenthal R, Romano A. Reconsolidation or extinction: transcription factor switch in the determination of memory course after retrieval. J Neurosci 31(15): 5562-73 (2011).
    • (2011) J Neurosci , vol.31 , Issue.15 , pp. 5562-5573
    • de la Fuente, V.1    Freudenthal, R.2    Romano, A.3
  • 37
    • 70350454809 scopus 로고    scopus 로고
    • Cognitive decline in Alzheimer's disease is associated with selective changes in calcineurin/NFAT signaling
    • Abdul HM, Sama MA, Furman JL, Mathis DM, Beckett TL, Weidner AM, et al. Cognitive decline in Alzheimer's disease is associated with selective changes in calcineurin/NFAT signaling. J Neurosci 29(41): 12957-69 (2009).
    • (2009) J Neurosci , vol.29 , Issue.41 , pp. 12957-12969
    • Abdul, H.M.1    Sama, M.A.2    Furman, J.L.3    Mathis, D.M.4    Beckett, T.L.5    Weidner, A.M.6
  • 39
    • 0030983079 scopus 로고    scopus 로고
    • Transcription factor NF-kappaB is activated in primary neurons by amyloid beta peptides and in neurons surrounding early plaques from patients with Alzheimer disease
    • Kaltschmidt B, Uherek M, Volk B, Baeuerle PA, Kaltschmidt C. Transcription factor NF-kappaB is activated in primary neurons by amyloid beta peptides and in neurons surrounding early plaques from patients with Alzheimer disease. Proc Natl Acad Sci USA 94(6): 2642-7 (1997).
    • (1997) Proc Natl Acad Sci USA , vol.94 , Issue.6 , pp. 2642-2647
    • Kaltschmidt, B.1    Uherek, M.2    Volk, B.3    Baeuerle, P.A.4    Kaltschmidt, C.5
  • 40
    • 6944231363 scopus 로고    scopus 로고
    • Gene structure and organization of the human beta-secretase (BACE) promoter
    • Sambamurti K, Kinsey R, Maloney B, Ge YW, Lahiri DK. Gene structure and organization of the human beta-secretase (BACE) promoter. Faseb J 18(9): 1034-6 (2004).
    • (2004) Faseb J , vol.18 , Issue.9 , pp. 1034-1036
    • Sambamurti, K.1    Kinsey, R.2    Maloney, B.3    Ge, Y.W.4    Lahiri, D.K.5
  • 41
    • 84863798868 scopus 로고    scopus 로고
    • Nuclear factor-kappaB regulates betaAPP and beta-and gamma-secretases differently at physiological and supraphysiological Abeta concentrations
    • Chami L, Buggia-Prevot V, Duplan E, Delprete D, Chami M, Peyron JF, et al. Nuclear factor-kappaB regulates betaAPP and beta-and gamma-secretases differently at physiological and supraphysiological Abeta concentrations. J Biol Chem 287(29): 24573-84 (2012).
    • (2012) J Biol Chem , vol.287 , Issue.29 , pp. 24573-24584
    • Chami, L.1    Buggia-Prevot, V.2    Duplan, E.3    Delprete, D.4    Chami, M.5    Peyron, J.F.6
  • 42
    • 84873802341 scopus 로고    scopus 로고
    • Inhibition of GSK3beta-mediated BACE1 expression reduces Alzheimer-associated phenotypes
    • Ly PT, Wu Y, Zou H, Wang R, Zhou W, Kinoshita A, et al. Inhibition of GSK3beta-mediated BACE1 expression reduces Alzheimer-associated phenotypes. J Clin Invest 123(1): 224-35 (2013).
    • (2013) J Clin Invest , vol.123 , Issue.1 , pp. 224-235
    • Ly, P.T.1    Wu, Y.2    Zou, H.3    Wang, R.4    Zhou, W.5    Kinoshita, A.6
  • 43
    • 84856428468 scopus 로고    scopus 로고
    • Increased NF-kappaB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease
    • Chen CH, Zhou W, Liu S, Deng Y, Cai F, Tone M, et al. Increased NF-kappaB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease. Int J Neuropsychopharmacol 15(01): 77-90 (2012).
    • (2012) Int J Neuropsychopharmacol , vol.15 , Issue.1 , pp. 77-90
    • Chen, C.H.1    Zhou, W.2    Liu, S.3    Deng, Y.4    Cai, F.5    Tone, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.