Desensitization by different strategies of epidermal growth factor receptor and ErbB4

Journal of Pharmacological Sciences

Volumn 124, Issue 3, 2014, Pages 287-293

  Yamamoto, Hideyuki ^a   Higa Nakamine, Sayomi ^a   Noguchi, Nobuhiro ^a   Maeda, Noriko ^a   Kondo, Yutaka ^a   Toku, Seikichi ^a   Kukita, Ichiro ^a   Sugahara, Kazuhiro ^a  

^a UNIVERSITY OF THE RYUKYUS   (Japan)

Author keywords

Alveolar epithelial cell; Epidermal growth factor receptor (EGFR); ErbB4; Gonadotropin releasing hormone (GnRH); Hypothalamic neuron

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 4; FLAGELLIN; GONADORELIN; MAP KINASE ACTIVATED PROTEIN KINASE 2; PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

CELL DIVISION; CELL FUNCTION; ENDOCYTOSIS; ENZYME ACTIVATION; GONADORELIN RELEASE; HUMAN; HYPOTHALAMUS; LUNG ALVEOLUS EPITHELIUM; NONHUMAN; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; RECEPTOR DOWN REGULATION; REVIEW; SIGNAL TRANSDUCTION; TRANSACTIVATION;

ANIMALS; CELL LINE; EPITHELIAL CELLS; FLAGELLIN; GONADOTROPIN-RELEASING HORMONE; HUMANS; HYPOTHALAMUS; MAP KINASE SIGNALING SYSTEM; NEURONS; PHOSPHORYLATION; PROTEIN KINASE C; PULMONARY ALVEOLI; RECEPTOR, EPIDERMAL GROWTH FACTOR; SERINE; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84897379109     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.13R11CP     Document Type: Review

References (28)

1. Carpenter G. ErbB-4: mechanism of action and biology. Exp Cell Res. 2003;284:66-77. (Pubitemid 36331966)
2. Wiley HS. Trafficking of the ErbB receptors and its influence on signaling. Exp Cell Res. 2003;284:78-88. (Pubitemid 36331967)
3. Zhou W, Carpenter G. Heregulin-dependent trafficking and cleavage of ErbB-4. J Biol Chem. 2000;275:34737-34743.
4. Vecchi M, Baulida J, Carpenter G. Selective cleavage of the heregulin receptor ErbB-4 by protein kinase C activation. J Biol Chem. 1996;271:18989-18995. (Pubitemid 26322776)
5. Argast GM, Campbell JS, Brooling JT, Fausto N. Epidermal growth factor receptor transactivation mediates tumor necrosis factor-induced hepatocyte replication. J Biol Chem. 2004;279:34530-34536. (Pubitemid 39318081)
6. Shibata T, Takaguri A, Ichihara K, Satoh K. Inhibition of the TNF-α-induced serine phosphorylation of IRS-1 at 636/639 by AICAR. J Pharmacol Sci. 2013;122:93-102.
7. Singhirunnusorn P, Ueno Y, Matsuo M, Suzuki S, Saiki I, Sakurai H. Transient suppression of ligand-mediated activation of epidermal growth factor receptor by tumor necrosis factor-α through the TAK1-p38 signaling pathway. J Biol Chem. 2007;282:12698-12706. (Pubitemid 47100631)
8. Yang X, Yao J, Luo Y, Han Y, Wang Z, Du L. P38 MAP kinase mediates apoptosis after genipin treatment in non-small-cell lung cancer H1299 cells via a mitochondrial apoptotic cascade. J Pharmacol Sci. 2013;121:272-281.
9. Kuwahara I, Lillehoj EP, Lu W, Singh IS, Isohama Y, Miyata T, et al. Neutrophil elastase induces IL-8 gene transcription and protein release through p38/NF-κB activation via EGFR transactivation in a lung epithelial cell line. Am J Physiol Lung Cell Mol Physiol. 2006;291:L407-L416. (Pubitemid 44343717)
10. Mizutani A, Maeda N, Toku S, Isohama Y, Sugahara K, Yamamoto H. Inhibition by ethyl pyruvate of the nuclear translocation of nuclear factor-κB in cultured lung epithelial cells. Pulm Pharmacol Ther. 2010;23:308-315.
11. Noguchi N, Kondo Y, Maeda N, Higa-Nakamine S, Toku S, Maruyama J, et al. Phosphorylation of epidermal growth factor receptor at serine 1047 by MAP kinase-activated protein kinase-2 in cultured lung epithelial cells treated with flagellin. Arch Biochem Biophys. 2013;529:75-85.
12. Huang F, Kirkpatrick D, Jiang X, Gygi S, Sorkin A. Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain. Mol Cell. 2006;21:737-748. (Pubitemid 43376125)
13. Rouse J, Cohen P, Trigon S, Morange M, Alonso-Liamazares A, Zamanillo D, et al. A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins. Cell. 1994;78:1027-1037. (Pubitemid 24292330)
14. Landry J, Lambert H, Zhou M, Lavoie JN, Hickey E, Weber LA, et al. Human HSP27 is phosphorylated at serines 78 and 82 by heat shock and mitogen-activated kinases that recognize the same amino acid motif as S6 kinase II. J Biol Chem. 1992;267:794-803.
15. Ben-Levy R, Leighton IA, Doza YN, Attwood P, Morrice N, Marshall CJ, et al. Identification of novel phosphorylation sites required for activation of MAPKAP kinase-2. EMBO J. 1995;14:5920-5930.
16. Hayashi F, Smith KD, Ozinsky A, Hawn TR, Yi EC, Goodlett DR, et al. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature. 2001;410:1099-1103. (Pubitemid 32391041)
17. Sierro F, Dubois B, Coste A, Kaiserlian D, Kraehenbuhl JP, Sirard JC. Flagellin stimulation of intestinal epithelial cells triggers CCL20-mediated migration of dendritic cells. Proc Natl Acad Sci U S A. 2001;98:13722-13727.
18. Smith KD, Andersen-Nissen E, Hayashi F, Strobe K, Bergman MA, Barrett SLR, et al. Toll-like receptor 5 recognizes a conserved site on flagellin required for protofilament formation and bacterial motility. Nature Immun. 2003;4:1247-1253. (Pubitemid 37540694)
19. Ramos HC, Rumbo M, Sirard JC. Bacterial flagellins: mediators of pathogenicity and host immune responses in mucosa. Trends Microbiol. 2004;12:509-517. (Pubitemid 39370733)
20. Kondo Y, Higa-Nakamine S, Noguchi N, Maeda N, Toku S, Isohama Y, et al. Induction of epithelial-mesenchymal transition by flagellin in cultured lung epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2012;303:L1057-L1069.
21. Krsmanovic LZ, Stojilkovic SS, Mertz LM, Tomic M, Catt KJ. Expression of gonadotropin-releasing hormone receptors and autocrine regulation of neuropeptide release in immortalized hypothalamic neurons. Proc Natl Acad Sci U S A. 1993;90:3908-3912. (Pubitemid 23134135)
22. Mellon PL, Windle JJ, Goldsmith PC, Padula CA, Roberts JL, Weiner RI. Immortalization of hypothalamic GnRH neurons by genetically targeted tumorigenesis. Neuron. 1990;5:1-10. (Pubitemid 20224495)
23. Yamanaka A, Hiragami Y, Maeda N, Toku S, Kawahara M, Naito Y, et al. Involvement of CaM kinase II in gonadotropin-releasing hormone-induced activation of MAP kinase in cultured hypothalamic neurons. Arch Biochem Biophys. 2007;466:234-241. (Pubitemid 47451338)
24. Shah BH, Catt KJ. GPCR-mediated transactivation of RTKs in the CNS: mechanisms and consequences. Trends Neurosci. 2004;27:48-53. (Pubitemid 38036978)
25. Higa-Nakamine S, Maeda N, Toku S, Yamamoto T, Yingyuenyong M, Kawahara M, et al. Selective cleavage of ErbB4 by G-protein-coupled gonadotropin-releasing hormone receptor in cultured hypothalamic neurons. J Cell Physiol. 2012;227:2492-2501.
26. Rio C, Buxbaum JD, Peschon JJ, Corfas G. Tumor necrosis factor-α-converting enzyme is required for cleavage of erbB4/HER4. J Biol Chem. 2000;275:10379-10387. (Pubitemid 30202097)
27. Carpenter G, Liao HJ. Trafficking of receptor tyrosine kinases to the nucleus. Exp Cell Res. 2009;315:1556-1566.
28. Ishibashi K, Fukumoto Y, Hasegawa H, Abe K, Kubota S, Aoyama K, et al. Nuclear ErbB4 signaling through H3K9me3 that is antagonized by EGFR-activated c-Src. J Cell Sci. 2013;126:625-637.