Identification of the synaptic vesicle glycoprotein 2 receptor binding site in botulinum neurotoxin A

FEBS Letters

Volumn 588, Issue 7, 2014, Pages 1087-1093

  Strotmeier, Jasmin ^a   Mahrhold, Stefan ^a   Krez, Nadja ^a   Janzen, Constantin ^a   Lou, Jianlong ^b   Marks, James D ^b   Binz, Thomas ^a   Rummel, Andreas ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Botulinum neurotoxin A; Monoclonal antibody; Neutralisation; Protein receptor binding site; SV2

Indexed keywords

BOTULINUM TOXIN A; EPITOPE; GANGLIOSIDE; GLYCOPROTEIN; MONOCLONAL ANTIBODY; SYNAPTIC VESICLE GLYCOPROTEIN 2; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING; SITE DIRECTED MUTAGENESIS;

BOTULINUM NEUROTOXIN A; MONOCLONAL ANTIBODY; NEUTRALISATION; PROTEIN RECEPTOR BINDING SITE; SV2;

AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; BOTULINUM TOXINS, TYPE A; HUMANS; INHIBITORY CONCENTRATION 50; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MUTAGENESIS, SITE-DIRECTED; NERVE TISSUE PROTEINS; NEURAL CONDUCTION; NEUROTOXINS; PHRENIC NERVE; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS;

EID: 84897099717     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2014.02.034     Document Type: Article

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