-
1
-
-
2342439732
-
Leptin signaling in the central nervous system and the periphery
-
C. Bjorbaek, B.B. Kahn, Leptin signaling in the central nervous system and the periphery. Recent Prog. Horm. Res. 59, 305-331 (2004)
-
(2004)
Recent Prog. Horm. Res.
, vol.59
, pp. 305-331
-
-
Bjorbaek, C.1
Kahn, B.B.2
-
2
-
-
75749084837
-
Leptin and the control of body weight: A review of its diverse central targets, signaling mechanisms, and role in the pathogenesis of obesity
-
Silver Spring
-
A. Oswal, G. Yeo, Leptin and the control of body weight: a review of its diverse central targets, signaling mechanisms, and role in the pathogenesis of obesity. Obesity (Silver Spring) 18, 221-229 (2010)
-
(2010)
Obesity
, vol.18
, pp. 221-229
-
-
Oswal, A.1
Yeo, G.2
-
3
-
-
33845875966
-
Gut hormones and the regulation of energy homeostasis
-
K.G. Murphy, S.R. Bloom, Gut hormones and the regulation of energy homeostasis. Nature 444, 854-859 (2006)
-
(2006)
Nature
, vol.444
, pp. 854-859
-
-
Murphy, K.G.1
Bloom, S.R.2
-
4
-
-
17944379112
-
Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans
-
H. Ariyasu, K. Takaya, T. Tagami et al., Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans. J. Clin. Endocrinol. Metab. 86, 4753-4758 (2001)
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 4753-4758
-
-
Ariyasu, H.1
Takaya, K.2
Tagami, T.3
-
5
-
-
72449192299
-
Ghrelin in the regulation of body weight and metabolism
-
T.R. Castaneda, J. Tong, R. Datta, M. Culler, M.H. Tschop, Ghrelin in the regulation of body weight and metabolism. Front. Neuroendocrinol. 31, 44-60 (2010)
-
(2010)
Front. Neuroendocrinol.
, vol.31
, pp. 44-60
-
-
Castaneda, T.R.1
Tong, J.2
Datta, R.3
Culler, M.4
Tschop, M.H.5
-
6
-
-
0036075862
-
Food fails to suppress ghrelin levels in obese humans
-
P.J. English, M.A. Ghatei, I.A. Malik, S.R. Bloom, J.P. Wilding, Food fails to suppress ghrelin levels in obese humans. J. Clin. Endocrinol. Metab. 87, 2984-2987 (2002)
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 2984-2987
-
-
English, P.J.1
Ghatei, M.A.2
Malik, I.A.3
Bloom, S.R.4
Wilding, J.P.5
-
7
-
-
13444265857
-
Weight gain decreases elevated plasma ghrelin concentrations of patients with anorexia nervosa
-
B. Otto, U. Cuntz, E. Fruehauf, R. Wawarta et al., Weight gain decreases elevated plasma ghrelin concentrations of patients with anorexia nervosa. Eur. J. Endocrinol. 145, 669-673 (2001)
-
(2001)
Eur. J. Endocrinol.
, vol.145
, pp. 669-673
-
-
Otto, B.1
Cuntz, U.2
Fruehauf, E.3
Wawarta, R.4
-
8
-
-
84873672056
-
Postprandial total ghrelin suppression is modulated by melanocortin signaling in humans
-
A.A. van der Klaauw, J.M. Keogh, E. Henning, A. Blackwood, A.M. Haqq, J.Q. Purnell, I.S. Farooqi, Postprandial total ghrelin suppression is modulated by melanocortin signaling in humans. J. Clin. Endocrinol. Metab. 98, E288-E292 (2013)
-
(2013)
J. Clin. Endocrinol. Metab.
, vol.98
-
-
Van Der Klaauw, A.A.1
Keogh, J.M.2
Henning, E.3
Blackwood, A.4
Haqq, A.M.5
Purnell, J.Q.6
Farooqi, I.S.7
-
9
-
-
0037240916
-
Serum ghrelin levels are inversely correlated with body mass index, age, and insulin concentrations in normal children and are markedly increased in Prader-Willi syndrome
-
A.M. Haqq, I.S. Farooqi, S. O'Rahilly et al., Serum ghrelin levels are inversely correlated with body mass index, age, and insulin concentrations in normal children and are markedly increased in Prader-Willi syndrome. J. Clin. Endocrinol. Metab. 88, 174-178 (2003)
-
(2003)
J. Clin. Endocrinol. Metab.
, vol.88
, pp. 174-178
-
-
Haqq, A.M.1
Farooqi, I.S.2
O'Rahilly, S.3
-
10
-
-
18844416580
-
Fasting and postprandial hyperghrelinemia in Prader-Willi syndrome is partially explained by hypoinsulinemia, and is not due to peptide YY3-36 deficiency or seen in hypothalamic obesity due to craniopharyngioma
-
A.P. Goldstone, M. Patterson, N. Kalingag et al., Fasting and postprandial hyperghrelinemia in Prader-Willi syndrome is partially explained by hypoinsulinemia, and is not due to peptide YY3-36 deficiency or seen in hypothalamic obesity due to craniopharyngioma. J. Clin. Endocrinol. Metab. 90, 2681-2690 (2005)
-
(2005)
J. Clin. Endocrinol. Metab.
, vol.90
, pp. 2681-2690
-
-
Goldstone, A.P.1
Patterson, M.2
Kalingag, N.3
-
11
-
-
0036161876
-
Distribution of pancreatic polypeptide and peptide YY
-
E. Ekblad, F. Sundler, Distribution of pancreatic polypeptide and peptide YY. Peptides 23, 251-261 (2002)
-
(2002)
Peptides
, vol.23
, pp. 251-261
-
-
Ekblad, E.1
Sundler, F.2
-
12
-
-
33748128913
-
Critical role for peptide YY in protein-mediated satiation and body-weight regulation
-
R.L. Batterham, H. Heffron, S. Kapoor et al., Critical role for peptide YY in protein-mediated satiation and body-weight regulation. Cell Metab. 4, 223-233 (2006)
-
(2006)
Cell Metab.
, vol.4
, pp. 223-233
-
-
Batterham, R.L.1
Heffron, H.2
Kapoor, S.3
-
13
-
-
0022398837
-
Human distribution and release of a putative new gut hormone, peptide YY
-
T.E. Adrian, G.L. Ferri, A.J. Bacarese-Hamilton, H.S. Fuessl, J.M. Polak, S.R. Bloom, Human distribution and release of a putative new gut hormone, peptide YY. Gastroenterology 89, 1070-1077 (1985)
-
(1985)
Gastroenterology
, vol.89
, pp. 1070-1077
-
-
Adrian, T.E.1
Ferri, G.L.2
Bacarese-Hamilton, A.J.3
Fuessl, H.S.4
Polak, J.M.5
Bloom, S.R.6
-
14
-
-
84883172062
-
High protein intake stimulates postprandial GLP1 and PYY release
-
Silver Spring doi:10.1002/oby.20154
-
A.A. van der Klaauw, J.M. Keogh, E. Henning, V.M. Trowse, W.S. Dhillo, M.A. Ghatei, I.S. Farooqi, High protein intake stimulates postprandial GLP1 and PYY release. Obesity (Silver Spring) (2012). doi:10.1002/oby.20154
-
(2012)
Obesity
-
-
Van Der Klaauw, A.A.1
Keogh, J.M.2
Henning, E.3
Trowse, V.M.4
Dhillo, W.S.5
Ghatei, M.A.6
Farooqi, I.S.7
-
16
-
-
34948875154
-
Basal and postprandial plasma levels of PYY, ghrelin, cholecystokinin, gastrin and insulin in women with moderate and morbid obesity and metabolic syndrome
-
K. Zwirska-Korczala, S.J. Konturek, M. Sodowski et al., Basal and postprandial plasma levels of PYY, ghrelin, cholecystokinin, gastrin and insulin in women with moderate and morbid obesity and metabolic syndrome. J. Physiol. Pharmacol. 58(Suppl 1), 13-35 (2007)
-
(2007)
J. Physiol. Pharmacol.
, vol.58
, Issue.SUPPL. 1
, pp. 13-35
-
-
Zwirska-Korczala, K.1
Konturek, S.J.2
Sodowski, M.3
-
17
-
-
13344282056
-
A role for glucagon-like peptide-1 in the central regulation of feeding
-
M.D. Turton, D. O'Shea, I. Gunn, S.A. Beak et al., A role for glucagon-like peptide-1 in the central regulation of feeding. Nature 379, 69-72 (1996)
-
(1996)
Nature
, vol.379
, pp. 69-72
-
-
Turton, M.D.1
O'Shea, D.2
Gunn, I.3
Beak, S.A.4
-
19
-
-
0037288941
-
Insulin and leptin revisited: Adiposity signals with overlapping physiological and intracellular signaling capabilities
-
K.D. Niswender, M.W. Schwartz, Insulin and leptin revisited: adiposity signals with overlapping physiological and intracellular signaling capabilities. Front. Neuroendocrinol. 24, 1-10 (2003)
-
(2003)
Front. Neuroendocrinol.
, vol.24
, pp. 1-10
-
-
Niswender, K.D.1
Schwartz, M.W.2
-
20
-
-
0034611732
-
Central nervous system control of food intake
-
M.W. Schwartz, S.C. Woods, D. Porte Jr, R.J. Seeley, D.G. Baskin, Central nervous system control of food intake. Nature 404, 661-671 (2000)
-
(2000)
Nature
, vol.404
, pp. 661-671
-
-
Schwartz, M.W.1
Woods, S.C.2
Porte Jr., D.3
Seeley, R.J.4
Baskin, D.G.5
-
21
-
-
2942528459
-
Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin
-
A.J. van der Lely, M. Tschop, M.L. Heiman, E. Ghigo, Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin. Endocr. Rev. 25, 426-457 (2004)
-
(2004)
Endocr. Rev.
, vol.25
, pp. 426-457
-
-
Van Der Lely, A.J.1
Tschop, M.2
Heiman, M.L.3
Ghigo, E.4
-
22
-
-
0030878110
-
Congenital leptin deficiency is associated with severe early-onset obesity in humans
-
C.T. Montague, I.S. Farooqi, J.P. Whitehead et al., Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature 387, 903-908 (1997)
-
(1997)
Nature
, vol.387
, pp. 903-908
-
-
Montague, C.T.1
Farooqi, I.S.2
Whitehead, J.P.3
-
24
-
-
84860211766
-
High prevalence of leptin and melanocortin-4 receptor gene mutations in children with severe obesity from Pakistani consanguineous families
-
S. Saeed, T.A. Butt, M. Anwer, M. Arslan, P. Froguel, High prevalence of leptin and melanocortin-4 receptor gene mutations in children with severe obesity from Pakistani consanguineous families. Mol. Genet. Metab. 106, 121-126 (2012)
-
(2012)
Mol. Genet. Metab.
, vol.106
, pp. 121-126
-
-
Saeed, S.1
Butt, T.A.2
Anwer, M.3
Arslan, M.4
Froguel, P.5
-
25
-
-
78650315390
-
Investigation of Mendelian forms of obesity holds out the prospect of personalized medicine
-
A.I. Blakemore, P. Froguel, Investigation of Mendelian forms of obesity holds out the prospect of personalized medicine. Ann. N. Y. Acad. Sci. 1214, 180-189 (2010)
-
(2010)
Ann. N. Y. Acad. Sci.
, vol.1214
, pp. 180-189
-
-
Blakemore, A.I.1
Froguel, P.2
-
26
-
-
0035514934
-
Partial leptin deficiency and human adiposity
-
I.S. Farooqi, J.M. Keogh, S. Kamath et al., Partial leptin deficiency and human adiposity. Nature 414, 34-35 (2001)
-
(2001)
Nature
, vol.414
, pp. 34-35
-
-
Farooqi, I.S.1
Keogh, J.M.2
Kamath, S.3
-
27
-
-
0035216623
-
Ghrelin enhances appetite and increases food intake in humans
-
A.M. Wren, L.J. Seal, M.A. Cohen et al., Ghrelin enhances appetite and increases food intake in humans. J. Clin. Endocrinol. Metab. 86, 5992-5995 (2001)
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 5992-5995
-
-
Wren, A.M.1
Seal, L.J.2
Cohen, M.A.3
-
28
-
-
0035082265
-
Circulating ghrelin levels are decreased in human obesity
-
M. Tschop, C. Weyer, P.A. Tataranni, V. Devanarayan, E. Ravussin, M.L. Heiman, Circulating ghrelin levels are decreased in human obesity. Diabetes 50, 707-709 (2001)
-
(2001)
Diabetes
, vol.50
, pp. 707-709
-
-
Tschop, M.1
Weyer, C.2
Tataranni, P.A.3
Devanarayan, V.4
Ravussin, E.5
Heiman, M.L.6
-
29
-
-
0242580169
-
Deletion of ghrelin impairs neither growth nor appetite
-
Y. Sun, S. Ahmed, R.G. Smith, Deletion of ghrelin impairs neither growth nor appetite. Mol. Cell. Biol. 23, 7973-7981 (2003)
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 7973-7981
-
-
Sun, Y.1
Ahmed, S.2
Smith, R.G.3
-
30
-
-
84876444692
-
Ablation of ghrelin O-acyltransferase does not improve glucose intolerance or body adiposity in mice on a leptin-deficient ob/ob background
-
H. Kirchner, K.M. Heppner, J. Holland, D. Kabra, M.H. Tschöp, P.T. Pfluger, Ablation of ghrelin O-acyltransferase does not improve glucose intolerance or body adiposity in mice on a leptin-deficient ob/ob background. PLoS One 8, e61822 (2013)
-
(2013)
PLoS One
, vol.8
-
-
Kirchner, H.1
Heppner, K.M.2
Holland, J.3
Kabra, D.4
Tschöp, M.H.5
Pfluger, P.T.6
-
31
-
-
3142658638
-
Alterations in the dynamics of circulating ghrelin, adiponectin, and leptin in human obesity
-
B.O. Yildiz, M.A. Suchard, M.L. Wong, S.M. McCann, J. Licinio, Alterations in the dynamics of circulating ghrelin, adiponectin, and leptin in human obesity. Proc. Natl. Acad. Sci. USA. 101, 10434-10439 (2004)
-
(2004)
Proc. Natl. Acad. Sci. USA.
, vol.101
, pp. 10434-10439
-
-
Yildiz, B.O.1
Suchard, M.A.2
Wong, M.L.3
McCann, S.M.4
Licinio, J.5
-
32
-
-
77149142591
-
Children with Prader-Willi syndrome exhibit more evident meal-induced responses in plasma ghrelin and peptide YY levels than obese and lean children
-
C. Bizzarri, A.E. Rigamonti, A. Luce et al., Children with Prader-Willi syndrome exhibit more evident meal-induced responses in plasma ghrelin and peptide YY levels than obese and lean children. Eur. J. Endocrinol. 162, 499-505 (2010)
-
(2010)
Eur. J. Endocrinol.
, vol.162
, pp. 499-505
-
-
Bizzarri, C.1
Rigamonti, A.E.2
Luce, A.3
-
33
-
-
17944374136
-
Visceral adipose tissue and metabolic complications of obesity are reduced in Prader-Willi syndrome female adults: Evidence for novel influences on body fat distribution
-
A.P. Goldstone, E.L. Thomas, A.E. Brynes et al., Visceral adipose tissue and metabolic complications of obesity are reduced in Prader-Willi syndrome female adults: evidence for novel influences on body fat distribution. J. Clin. Endocrinol. Metab. 86, 4330-4338 (2001)
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 4330-4338
-
-
Goldstone, A.P.1
Thomas, E.L.2
Brynes, A.E.3
-
34
-
-
79960839413
-
In adults with Prader-Willi syndrome, elevated ghrelin levels are more consistent with hyperphagia than high PYY and GLP-1 levels
-
L. Purtell, L. Sze, G. Loughnan et al., In adults with Prader-Willi syndrome, elevated ghrelin levels are more consistent with hyperphagia than high PYY and GLP-1 levels. Neuropeptides 4, 301-307 (2011)
-
(2011)
Neuropeptides
, vol.4
, pp. 301-307
-
-
Purtell, L.1
Sze, L.2
Loughnan, G.3
-
35
-
-
84856080046
-
Gut hormones and appetite control: A focus on PYY and GLP-1 as therapeutic targets in obesity
-
A. De Silva, S.R. Bloom, Gut hormones and appetite control: a focus on PYY and GLP-1 as therapeutic targets in obesity. Gut Liver 6, 10-20 (2012)
-
(2012)
Gut Liver
, vol.6
, pp. 10-20
-
-
De Silva, A.1
Bloom, S.R.2
-
36
-
-
31444436982
-
Peptide YY levels are decreased by fasting and elevated following caloric intake but are not regulated by leptin
-
J.L. Chan, V. Stoyneva, T. Kelesidis, P. Raciti, C.S. Mantzoros, Peptide YY levels are decreased by fasting and elevated following caloric intake but are not regulated by leptin. Diabetologia 49, 169-173 (2006)
-
(2006)
Diabetologia
, vol.49
, pp. 169-173
-
-
Chan, J.L.1
Stoyneva, V.2
Kelesidis, T.3
Raciti, P.4
Mantzoros, C.S.5
-
37
-
-
0030738331
-
Leptin levels do not change acutely with food administration in normal or obese subjects, but are negatively correlated with pituitary-adrenal activity
-
Oxf.
-
M. Korbonits, P.J. Trainer, J.A. Little et al., Leptin levels do not change acutely with food administration in normal or obese subjects, but are negatively correlated with pituitary-adrenal activity. Clin. Endocrinol. (Oxf.) 46, 751-757 (1997)
-
(1997)
Clin. Endocrinol.
, vol.46
, pp. 751-757
-
-
Korbonits, M.1
Trainer, P.J.2
Little, J.A.3
-
38
-
-
0038792479
-
Postprandial leptin response to carbohydrate and fat meals in obese women
-
M. Romon, P. Lebel, J.C. Fruchart, J. Dallongeville, Postprandial leptin response to carbohydrate and fat meals in obese women. J. Am. Coll. Nutr. 22, 247-251 (2003)
-
(2003)
J. Am. Coll. Nutr.
, vol.22
, pp. 247-251
-
-
Romon, M.1
Lebel, P.2
Fruchart, J.C.3
Dallongeville, J.4
-
39
-
-
0031851995
-
Short term response of circulating leptin to feeding and fasting in man: Influence of circadian cycle
-
J. Dallongeville, B. Hecquet, P. Lebel et al., Short term response of circulating leptin to feeding and fasting in man: influence of circadian cycle. Int. J. Obes. Relat. Metab. Disord. 22, 728-733 (1998)
-
(1998)
Int. J. Obes. Relat. Metab. Disord.
, vol.22
, pp. 728-733
-
-
Dallongeville, J.1
Hecquet, B.2
Lebel, P.3
-
40
-
-
0036800760
-
Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency
-
I.S. Farooqi, G. Matarese, G.M. Lord et al., Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency. J. Clin. Invest. 110, 1093-1103 (2002)
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 1093-1103
-
-
Farooqi, I.S.1
Matarese, G.2
Lord, G.M.3
-
41
-
-
80052496890
-
Acute disruption of leptin signaling in vivo leads to increased insulin levels and insulin resistance
-
J. Levi, S.L. Gray, M. Speck et al., Acute disruption of leptin signaling in vivo leads to increased insulin levels and insulin resistance. Endocrinology 152, 3385-3395 (2011)
-
(2011)
Endocrinology
, vol.152
, pp. 3385-3395
-
-
Levi, J.1
Gray, S.L.2
Speck, M.3
-
42
-
-
0022515702
-
Age effects on glycosylated blood proteins in lean and obese hyperglycaemic (ob/ob) mice
-
P.R. Flatt, C.J. Bailey, A.M. Cameron, B.J. Gould, Age effects on glycosylated blood proteins in lean and obese hyperglycaemic (ob/ob) mice. Diabetes Res. 3, 241-243 (1986)
-
(1986)
Diabetes Res.
, vol.3
, pp. 241-243
-
-
Flatt, P.R.1
Bailey, C.J.2
Cameron, A.M.3
Gould, B.J.4
-
43
-
-
0033582239
-
Leptin inhibits insulin gene transcription and reverses hyperinsulinemia in leptin-deficient ob/ob mice
-
J. Seufert, T.J. Kieffer, J.F. Habener, Leptin inhibits insulin gene transcription and reverses hyperinsulinemia in leptin-deficient ob/ob mice. Proc. Natl. Acad. Sci. USA. 96, 674-679 (1999)
-
(1999)
Proc. Natl. Acad. Sci. USA.
, vol.96
, pp. 674-679
-
-
Seufert, J.1
Kieffer, T.J.2
Habener, J.F.3
-
44
-
-
33646141847
-
Ablation of ghrelin improves the diabetic but not obese phenotype of ob/ob mice
-
Y. Sun, M. Asnicar, P.K. Saha, L. Chan, R.G. Smith, Ablation of ghrelin improves the diabetic but not obese phenotype of ob/ob mice. Cell Metab. 3, 379-386 (2006)
-
(2006)
Cell Metab.
, vol.3
, pp. 379-386
-
-
Sun, Y.1
Asnicar, M.2
Saha, P.K.3
Chan, L.4
Smith, R.G.5
|