Chemoprevention by lipid-soluble tea polyphenols in diethylnitrosamine/phenobarbital-induced hepatic pre-cancerous lesions

Anticancer Research

Volumn 34, Issue 2, 2014, Pages 683-694

  Shen, Ting ^a,b   Khor, Soo Chin ^a   Zhou, Fan ^a,c   Duan, Ting ^a   Xu, Yu Ying ^a   Zheng, Yi Fan ^a   Hsu, Stephen ^d   De Stefano, Jamie ^d   Yang, Jun ^e   Xu, Li Hong ^f   Zhu, Xin Qiang ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b Xihu District Center for Disease Control and Prevention   (China)

^c Shanghai Minhang District Hospital   (China)

^d AUGUSTA UNIVERSITY   (United States)

^e HANGZHOU NORMAL UNIVERSITY   (China)

^f ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

DNA damage; GTPs; LTPs; Precancerous lesions; Proliferation

Indexed keywords

DIETHYLNITROSAMINE; DNA; GLUTATHIONE TRANSFERASE; GREEN TEA EXTRACT; PHENOBARBITAL; POLYPHENOL; LIPID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CANCER INHIBITION; CANCER PREVENTION; CELL PROLIFERATION; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DNA DAMAGE; DRUG MECHANISM; ELECTRON MICROSCOPY; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LIVER CANCER; LIVER FIBROSIS; LIVER WEIGHT; NONHUMAN; PRECANCER; RAT; TEA; ANIMAL; CELL GROWTH; CHEMICALLY INDUCED DISORDER; CHEMISTRY; DRUG EFFECT; EXPERIMENTAL LIVER NEOPLASM; GTPS; LIVER; LIVER CIRRHOSIS; LTPS; MALE; ORGAN SIZE; PATHOLOGY; PRECANCEROUS LESIONS; PROLIFERATION; SOLUBILITY; SPRAGUE DAWLEY RAT;

DNA DAMAGE; GTPS; LTPS; PRECANCEROUS LESIONS; PROLIFERATION;

ANIMALS; CELL GROWTH PROCESSES; DIETHYLNITROSAMINE; DNA DAMAGE; IMMUNOHISTOCHEMISTRY; LIPIDS; LIVER; LIVER CIRRHOSIS; LIVER NEOPLASMS, EXPERIMENTAL; MALE; ORGAN SIZE; PHENOBARBITAL; POLYPHENOLS; PRECANCEROUS CONDITIONS; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY; TEA;

EID: 84897038380     PISSN: 02507005     EISSN: 17917530     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. Jemal A, Bray F, Center MM, Ferlay J, Ward E and Forman D: Global cancer statistics. CA Cancer J Clin 61: 69-90, 2011.
2. Bosch FX, Ribes J, Diaz M and Cleries R: Primary liver cancer: worldwide incidence and trends. Gastroenterology 127: S5-S16, 2004.
3. Feo F, Pascale RM, Simile MM, De Miglio MR, Muroni MR and Calvisi D: Genetic alterations in liver carcinogenesis: implications for new preventive and therapeutic strategies. Crit Rev Oncog 11: 19-62, 2000.
4. McGlynn KA and London WT: Epidemiology and natural history of hepatocellular carcinoma. Best Pract Res Clin Gastroenterol 19: 3-23, 2005.
5. Shih WL, Yu MW, Chen PJ, Wu TW, Lin CL, Liu CJ, Lin SM, Tai DI, Lee SD and Liaw YF: Evidence for association with hepatocellular carcinoma at the PAPSS1 locus on chromosome 4q25 in a family-based study. Eur J Hum Genet 17: 1250-1259, 2009.
6. Kumar V, Kato N, Urabe Y, Takahashi A, Muroyama R, Hosono N, Otsuka M, Tateishi R, Omata M, Nakagawa H, Koike K, Kamatani N, Kubo M, Nakamura Y and Matsuda K: Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma. Nat Genet 43: 455-458, 2011.
7. Feo F, De Miglio MR, Simile MM, Muroni MR, Calvisi DF, Frau M and Pascale RM: Hepatocellular carcinoma as a complex polygenic disease. Interpretive analysis of recent developments on genetic predisposition. Biochim Biophys Acta 1765: 126-147, 2006.
8. Sun H, Yu L, Wei H and Liu G: A novel antihepatitis drug, bicyclol, prevents liver carcinogenesis in diethylnitrosamine-initiated and phenobarbital-promoted mice tumor model. J Biomed Biotechnol 2012: 584728, 2012.
9. Sivaramakrishnan V, Shilpa PN, Praveen Kumar VR and Niranjali Devaraj S: Attenuation of N-nitrosodiethylamine-induced hepatocellular carcinogenesis by a novel flavonol-Morin. Chem Biol Interact 171: 79-88, 2008.
10. Llovet JM, Burroughs A and Bruix J: Hepatocellular carcinoma. Lancet 362: 1907-1917, 2003.
11. Bishayee A, Politis T and Darvesh AS: Resveratrol in the chemoprevention and treatment of hepatocellular carcinoma. Cancer Treat Rev 36: 43-53, 2010.
12. Bickers DR and Athar M: Novel approaches to chemoprevention of skin cancer. J Dermatol 27: 691-695, 2000.
13. Miller PE and Snyder DC: Phytochemicals and cancer risk: a review of the epidemiological evidence. Nutr Clin Pract 27: 599-612, 2012.
14. Stagos D, Amoutzias GD, Matakos A, Spyrou A, Tsatsakis AM and D Kouretas: Chemoprevention of liver cancer by plant polyphenols. Food Chem Toxicol 50: 2155-2170, 2012.
15. Yang CS, Chen L, Lee MJ, Balentine D, Kuo MC and Schantz SP: Blood and urine levels of tea catechins after ingestion of different amounts of green tea by human volunteers. Cancer Epidemiol Biomarkers Prev 7: 351-354, 1998.
16. Lee MJ, Maliakal P, Chen L, Meng X, Bondoc FY, Prabhu S, Lambert G, Mohr S and Yang CS: Pharmacokinetics of tea catechins after ingestion of green tea and (-)-epigallocatechin-3-gallate by humans: formation of different metabolites and individual variability. Cancer Epidemiol Biomarkers Prev 11: 1025-1032, 2002.
17. Chen P, D. D. and H. S.: Lipid- soluble green teapolyphenols: stabilized for effective formulation handbook of green tea and health research, 45-63, 2009.
18. Yang CS, Wang H, Li GX, Yang Z, Guan F and Jin H: Cancer prevention by tea: Evidence from laboratory studies. Pharmacol Res 64: 113-122, 2011.
19. Mukhtar H and Ahmad N: Tea polyphenols: prevention of cancer and optimizing health. Am J Clin Nutr 71: 1698S-702S; discussion 1703S-4S, 2000.
20. Yang CS, Maliakal P and Meng X: Inhibition of carcinogenesis by tea. Annu Rev Pharmacol Toxicol 42: 25-54, 2002.
21. Katiyar SK and Elmets CA: Green tea polyphenolic antioxidants and skin photoprotection (Review). Int J Oncol 18: 1307-1313, 2001.
22. Sueoka N, Suganuma M, Sueoka E, Okabe S, Matsuyama S, Imai K, Nakachi K and Fujiki H: A new function of green tea: prevention of lifestyle-related diseases. Ann NY Acad Sci 928: 274-280, 2001.
23. Imai K, Suga K and Nakachi K: Cancer-preventive effects of drinking green tea among a Japanese population. Prev Med 26: 769-775, 1997.
24. Haqqi TM, Anthony DD, Gupta S, Ahmad N, Lee MS, Kumar GK and Mukhtar H: Prevention of collagen-induced arthritis in mice by a polyphenolic fraction from green tea. Proc Natl Acad Sci USA 96: 4524-4529, 1999.
25. Imai K and Nakachi K: Cross sectional study of effects of drinking green tea on cardiovascular and liver diseases. BMJ 310: 693-696, 1995.
26. Frei B and Higdon JV: Antioxidant activity of tea polyphenols in vivo: evidence from animal studies. J Nutr 133: 3275S-3284S, 2003.
27. Hsu S and Dickinson D: A new approach to managing oral manifestations of Sjogren's syndrome and skin manifestations of lupus. J Biochem Mol Biol 39: 229-239, 2006.
28. Chung, JH, Han JH, Hwang EJ, Seo JY, Cho KH, Kim KH, Youn JI and Eun HC: Dual mechanisms of green tea extract (EGCG)-induced cell survival in human epidermal keratinocytes. FASEB J 17: 1913-1915, 2003.
29. Ishak K, Baptista A, Bianchi L, Callea F, De Groote J, Gudat F, Denk H, Desmet V, Korb G, MacSween RN et al: Histological grading and staging of chronic hepatitis. J Hepatol 22: 696-699, 1995.
30. Mizukami S, Ichimura R, Kemmochi S, Wang L, Taniai E, Mitsumori K and Shibutani M: Tumor promotion by copper-overloading and its enhancement by excess iron accumulation involving oxidative stress responses in the early stage of a rat two-stage hepatocarcinogenesis model. Chem Biol Interact 185: 189-201, 2010.
31. Dewa Y, Nishimura J, Muguruma M, Jin M, Saegusa Y, Okamura T, Tasaki M, Umemura T and Mitsumori K: beta-Naphthoflavone enhances oxidative stress responses and the induction of preneoplastic lesions in a diethylnitrosamine-initiated hepatocarcinogenesis model in partially hepatectomized rats. Toxicology 244: 179-189, 2008.
32. Amin A, Hamza AA, Bajbouj K, Ashraf SS and Daoud S: Saffron: a potential candidate for a novel anticancer drug against hepatocellular carcinoma. Hepatology 54: 857-867, 2011.
33. Crespy V and Williamson G: A review of the health effects of green tea catechins in in vivo animal models. J Nutr 134: 3431S-3440S, 2004.
34. Peto R, Gray R, Brantom P and Grasso P: Dose and time relationships for tumor induction in the liver and esophagus of 4080 inbred rats by chronic ingestion of N-nitrosodiethylamine or N-nitrosodimethylamine. Cancer Res 51: 6452-69, 1991.
35. Lee JS, Chu IS, Mikaelyan A, Calvisi DF, Heo J, Reddy JK and Thorgeirsson SS: Application of comparative functional genomics to identify best-fit mouse models to study human cancer. Nat Genet 36: 1306-1311, 2004.
36. Peraino C, Staffeldt EF and Ludeman VA: Early appearance of histochemically altered hepatocyte foci and liver tumors in female rats treated with carcinogens one day after birth. Carcinogenesis 2: 463-465, 1981.
37. Mihara M and Uchiyama M: Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Anal Biochem 86: 271-278, 1978.
38. Eriksson L, Ahluwalia M, Spiewak J, Lee G, Sarma DS, Roomi MJ and Farber E: Distinctive biochemical pattern associated with resistance of hepatocytes in hepatocyte nodules during liver carcinogenesis. Environ Health Perspect 49: 171-174, 1983.
39. Jin N, Deng J, Chadashvili T, Zhang Y, Guo Y, Zhang Z, Yang GY, Omary RA and Larson AC: Carbogen gas-challenge BOLD MR imaging in a rat model of diethylnitrosamine-induced liver fibrosis. Radiology 254: 129-137, 2010.
40. Kelman Z: PCNA: structure, functions and interactions. Oncogene 14: 629-640, 1997.
41. Naryzhny SN: Proliferating cell nuclear antigen: a proteomics view. Cell Mol Life Sci 65: 3789-808, 2008.
42. Eldrige SR, Butterworth BE and Goldsworthy TL: Proliferating cell nuclear antigen: a marker for hepatocellular proliferation in rodents. Environ Health Perspect 101(Suppl 5): 211-218, 1993.
43. Kasai H, Crain PF, Kuchino Y, Nishimura S, Ootsuyama A and Tanooka H: Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair. Carcinogenesis 7: 1849-1851, 1986.
44. Nyaga SG, Jaruga P, Lohani A, Dizdaroglu M and Evans MK: Accumulation of oxidatively induced DNA damage in human breast cancer cell lines following treatment with hydrogen peroxide. Cell Cycle 6: 1472-1478, 2007.
45. Cheng KC, Cahill DS, Kasai H, Nishimura S and Loeb LA: 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitutions. J Biol Chem 267: 166-172, 1992.
46. Irie M, Sohda T, Iwata K, Kunimoto H, Fukunaga A, Kuno S, Yotsumoto K, Sakurai K, Iwashita H, Hirano G, Ueda SI, Yokoyama K, Morihara D, Nishizawa S, Anan A, Takeyama Y, Sakamoto M, Shakado S and Sakisaka S: Levels of the oxidative stress marker γ-glutamyltranspeptidase at different stages of nonalcoholic fatty liver disease. The Jour nal of Inter national Medical Research 40: 924-933, 2012.
47. Tam NNC, Nyska A, Maronpot RR, Kissling G, Lomnitski L, Suttie A, Bakshi S, Bergman M, Grossman S and Ho a.S-M: Differential Attenuation of Oxidative/Nitrosative Injuries in Early Prostatic Neoplastic Lesions in TRAMP Mice by Dietary Antioxidants. heProstate 66: 57-69, 2006.
48. Xu SC, Chen YB, Lin H, Pi HF, Zhang NX, Zhao CC, Shuai L, Zhong M, Yu ZP, Zhou Z and Bie P: Damage to mtDNA in liver injury of patients with extrahepatic cholestasis: the protective effects of mitochondrial transcription factor A. Free Radic Biol Med 52: 1543-1551, 2012.
49. Shimamoto K, Dewa Y, Ishii Y, Kemmochi S, Taniai E, Hayashi H, Imaoka M, Morita R, Kuwata K, Suzuki K, Shibutani M and Mitsumori K: Indole-3-carbinol enhances oxidative stress responses resulting in the induction of preneoplastic liver cell lesions in partially hepatectomized rats initiated with diethylnitrosamine. Toxicology 283: 109-117, 2011.