Targeted STAT3 disruption in myeloid cells alters immunosuppressor cell abundance in a murine model of spontaneous medulloblastoma

Journal of Leukocyte Biology

Volumn 95, Issue 2, 2014, Pages 357-367

  Abad, Catalina ^a   Nobuta, Hiroko ^a   Li, Jiaxi ^a   Kasai, Atsushi ^a   Yong, William H ^b   Waschek, James A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Immunosuppression; Myeloid derived suppressor cell; STAT3

Indexed keywords

B7 ANTIGEN; CD11B ANTIGEN; CD86 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; STAT3 PROTEIN; G PROTEIN COUPLED RECEPTOR; SMO PROTEIN, MOUSE; STAT3 PROTEIN, MOUSE;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL POPULATION; CEREBELLUM; CONTROLLED STUDY; FEMALE; GENE DISRUPTION; IMMUNOCOMPETENT CELL; MACROPHAGE; MALE; MEDULLOBLASTOMA; MOUSE; MURINE MODEL; MYELOID DERIVED SUPPRESSOR CELL; NONHUMAN; PHENOTYPE; PRECANCER; PRIORITY JOURNAL; PROTEIN TARGETING; REGULATORY T LYMPHOCYTE; SUPPRESSOR CELL; TRANSGENIC MOUSE; TUMOR GROWTH; ANIMAL; C57BL MOUSE; DISEASE MODEL; GENE DELETION; GENE TARGETING; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; IMMUNOSUPPRESSIVE TREATMENT; INFLAMMATION; KNOCKOUT MOUSE; METABOLISM; MYELOID-DERIVED SUPPRESSOR CELL; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; SIGNAL TRANSDUCTION; VASCULARIZATION;

IMMUNOSUPPRESSION; MYELOID-DERIVED SUPPRESSOR CELL; STAT3;

ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; GENE DELETION; GENE TARGETING; IMMUNE TOLERANCE; INFLAMMATION; MALE; MEDULLOBLASTOMA; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYELOID CELLS; NEOVASCULARIZATION, PATHOLOGIC; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; T-LYMPHOCYTES, REGULATORY;

EID: 84897021573     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.1012531     Document Type: Article

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