The structure of human 15-lipoxygenase-2 with a substrate mimic

Journal of Biological Chemistry

Volumn 289, Issue 12, 2014, Pages 8562-8569

  Kobe, Matthew J ^a   Neau, David B ^b   Mitchell, Caitlin E ^a   Bartlett, Sue G ^a   Newcomer, Marcia E ^a  

^a LOUISIANA STATE UNIVERSITY   (United States)

^b ARGONNE NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS;

ACTIVE SITE; ATHEROSCLEROTIC PLAQUE; CHRONIC INFLAMMATION; FOAM CELLS; HYDROPHOBIC AMINO ACIDS; MEMBRANE BINDING;

CALCIUM;

15 LIPOXYGENASE 2; AMINO ACID; ARACHIDONATE 5 LIPOXYGENASE; CALCIUM; ENZYME INHIBITOR; LEUKOTRIENE; LIPOXYGENASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; ATHEROSCLEROSIS; BINDING SITE; COMPARATIVE STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; MEMBRANE BINDING; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ATHEROSCLEROSIS; EICOSANOID-SPECIFIC ENZYMES; FATTY ACID OXIDATION; LIPOXYGENASE PATHWAY; PROTEIN STRUCTURE;

ARACHIDONATE 15-LIPOXYGENASE; BINDING SITES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; HUMANS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 84897017271     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.543777     Document Type: Article

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