Post-traumatic hypoxia is associated with prolonged cerebral cytokine production, higher serum biomarker levels, and poor outcome in patients with severe traumatic brain injury

Journal of Neurotrauma

Volumn 31, Issue 7, 2014, Pages 618-629

  Yan, Edwin B ^a,b   Satgunaseelan, Laveniya ^a   Paul, Eldho ^b,c   Bye, Nicole ^a,b   Nguyen, Phuong ^a   Agyapomaa, Doreen ^a   Kossmann, Thomas ^d   Rosenfeld, Jeffrey V ^a,b   Morganti Kossmann, Maria Cristina ^a,b,c,e  

^a ALFRED HOSPITAL   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c Australian and New Zealand Intensive Care Research Centre   (Australia)

^d ANTWERP UNIVERSITY HOSPITAL   (Belgium)

^e UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

Biomarker; CSF serum albumin quotient; Hypoxia; Inflammation; TBI

Indexed keywords

ALBUMIN; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; MYELIN BASIC PROTEIN; NEURON SPECIFIC ENOLASE; PROTEIN S 100; TUMOR NECROSIS FACTOR;

ADOLESCENT; ADULT; ARTICLE; BLOOD BRAIN BARRIER; CEREBRAL CYTOKINE PRODUCTION; CEREBROSPINAL FLUID; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EXTRAVASATION; FEMALE; GLASGOW COMA SCALE; GLASGOW OUTCOME SCALE; HUMAN; HYPOXIA; MALE; MIDDLE AGED; NERVOUS SYSTEM INFLAMMATION; OUTCOME ASSESSMENT; TRAUMATIC BRAIN INJURY; YOUNG ADULT;

ADOLESCENT; ADULT; BIOLOGICAL MARKERS; BLOOD-BRAIN BARRIER; BRAIN INJURIES; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GLASGOW COMA SCALE; HUMANS; HYPOXIA, BRAIN; MALE; MIDDLE AGED; PROGNOSIS; RECOVERY OF FUNCTION; YOUNG ADULT;

EID: 84896956920     PISSN: 08977151     EISSN: 15579042     Source Type: Journal    
DOI: 10.1089/neu.2013.3087     Document Type: Article

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