Anti-inflammatory and anti-remodelling effects of ISU201, a modified form of the extracellular domain of human BST2, in experimental models of asthma: Association with inhibition of histone acetylation

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Herbert, Cristan ^a   Shadie, Alexander M ^a   Bunting, Melissa M ^a   Tedla, Nicodemus ^a   Garthwaite, Linda ^a   Freeman, Araluen ^a   Yoo, Hyouna ^b   Park, Sang Ho ^b   Kumar, Rakesh K ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b Isu Abxis Co Ltd   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; CELL SURFACE PROTEIN; CELL SURFACE PROTEIN BST2; CXCL1 CHEMOKINE; DEXAMETHASONE; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 13; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; ISU 201; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MESSENGER RNA; RANTES; UNCLASSIFIED DRUG; BST2 PROTEIN, HUMAN; CYTOKINE; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; HISTONE ACETYLTRANSFERASE; ISU201; LEUKOCYTE ANTIGEN; PEPTIDE FRAGMENT;

AIRWAY REMODELING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTI REMODELLING ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTHMA; CONTROLLED STUDY; DISEASE EXACERBATION; DRUG ACTIVITY; DRUG EFFECT; EPITHELIUM CELL; EXPERIMENTAL ASTHMA; FEMALE; HISTONE ACETYLATION; IN VITRO STUDY; LUNG LAVAGE; LYMPH NODE CELL; LYMPHOCYTE; MACROPHAGE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; RESPIRATORY TRACT INFLAMMATION; TARGET CELL; TISSUE REACTION; ANALYSIS OF VARIANCE; ANIMAL; BAGG ALBINO MOUSE; DRUG DEVELOPMENT; ENZYME IMMUNOASSAY; FLOW CYTOMETRY; GENETICS; METABOLISM;

ANALYSIS OF VARIANCE; ANIMALS; ANTIGENS, CD; ASTHMA; BRONCHOALVEOLAR LAVAGE; CYTOKINES; DEXAMETHASONE; DRUG DISCOVERY; EPITHELIAL CELLS; FEMALE; FLOW CYTOMETRY; GPI-LINKED PROTEINS; HISTONE ACETYLTRANSFERASES; IMMUNOENZYME TECHNIQUES; LYMPHOCYTES; MACROPHAGES; MICE; MICE, INBRED BALB C; PEPTIDE FRAGMENTS;

EID: 84896943345     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0090436     Document Type: Article

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