Heat exposure enhances radiosensitivity by depressing DNA-PK kinase activity during double strand break repair

International Journal of Hyperthermia

Volumn 30, Issue 2, 2014, Pages 102-109

  Ihara, Makoto ^a   Takeshita, Satoshi ^a   Okaichi, Kumio ^a   Okumura, Yutaka ^a   Ohnishi, Takeo ^b  

^a NAGASAKI UNIVERSITY   (Japan)

^b NARA MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

DNA repair; DNA PK kinase; Double strand break; Heat; Radiosensitivity

Indexed keywords

ATM PROTEIN; DNA DEPENDENT PROTEIN KINASE; PROTEIN; RAD51 PROTEIN; RPA70 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL SURVIVAL; CELL TYPE; CONTROLLED STUDY; DNA END JOINING REPAIR; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVITY; HEAT SENSITIVITY; HEAT TREATMENT; HUMAN; HUMAN CELL; HYBRID CELL; MOUSE; NONHUMAN; PULSED FIELD GEL ELECTROPHORESIS; RADIATION EXPOSURE; RADIOSENSITIVITY; RECOMBINATION REPAIR; SURVIVAL RATE; THERMAL EXPOSURE; WESTERN BLOTTING; WILD TYPE; X IRRADIATION; ANIMAL; CELL LINE; CHO CELL LINE; CRICETULUS; DEFICIENCY; DNA REPAIR; HEAT; METABOLISM; RADIATION DOSE; X RAY;

ANIMALS; CELL LINE; CELLS, CULTURED; CHO CELLS; CRICETULUS; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DNA-ACTIVATED PROTEIN KINASE; HOT TEMPERATURE; HUMANS; MICE; RADIATION TOLERANCE; X-RAYS;

EID: 84896896260     PISSN: 02656736     EISSN: 14645157     Source Type: Journal    
DOI: 10.3109/02656736.2014.887793     Document Type: Article

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