DNA complexed with TAT peptide and condensed using calcium possesses unique structural features compared to PEI polyplexes

International Journal of Pharmaceutics

Volumn 465, Issue 1-2, 2014, Pages 11-17

  Baoum, Abdulgader A ^a,b   Middaugh, C Russell ^b   Berkland, Cory ^b,c  

^a KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

^b UNIVERSITY OF KANSAS   (United States)

^c University of Kansas   (United States)

Author keywords

Biophysical characterization; Gene delivery; Polyelectrolyte complexes

Indexed keywords

CALCIUM; CELL PENETRATING PEPTIDE; DOUBLE STRANDED DNA; PLASMID DNA; POLYCATION; POLYELECTROLYTE; POLYETHYLENEIMINE; SUGAR PHOSPHATE; TRANSACTIVATOR PROTEIN; VIRUS VECTOR; DNA; PEPTIDE FRAGMENT; TAT PEPTIDE (49-57), HUMAN IMMUNODEFICIENCY VIRUS 1;

ABSORPTION SPECTROSCOPY; ARTICLE; CIRCULAR DICHROISM; COMPLEX FORMATION; CONTROLLED STUDY; CROSS LINKING; DIFFERENTIAL SCANNING CALORIMETRY; DNA CONFORMATION; DNA PROTEIN COMPLEX; FLUORESCENCE SPECTROSCOPY; GENE TARGETING; GENE TRANSLOCATION; GENE VECTOR; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HYDRODYNAMICS; IN VITRO GENE TRANSFER; INFRARED SPECTROSCOPY; LIGHT SCATTERING; LUNG CARCINOMA; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; SURFACE CHARGE; THERMOSTABILITY; ULTRAVIOLET SPECTROSCOPY; ZETA POTENTIAL; A549 CELL LINE; DNA TRANSFECTION; LIGHT ABSORPTION; MELTING POINT; CHEMISTRY; COMPARATIVE STUDY; CONFORMATION; GENETIC TRANSFECTION; LIGHT; METABOLISM; PROCEDURES; RADIATION SCATTERING; SPECTROFLUOROMETRY; TEMPERATURE; TUMOR CELL LINE; ULTRAVIOLET SPECTROPHOTOMETRY;

CALCIUM; CALORIMETRY, DIFFERENTIAL SCANNING; CELL LINE, TUMOR; CIRCULAR DICHROISM; DNA; HUMANS; LIGHT; NUCLEIC ACID CONFORMATION; PEPTIDE FRAGMENTS; POLYETHYLENEIMINE; SCATTERING, RADIATION; SPECTROMETRY, FLUORESCENCE; SPECTROPHOTOMETRY, ULTRAVIOLET; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TAT GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; TEMPERATURE; TRANSFECTION;

EID: 84896874328     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.01.040     Document Type: Article

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