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Volumn 9, Issue 2, 2014, Pages

DNA damage focus analysis in blood samples of minipigs reveals acute partial body irradiation

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DOUBLE STRANDED DNA; HISTONE; DNA BINDING PROTEIN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; SIGNAL PEPTIDE;

EID: 84896859116     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0087458     Document Type: Article
Times cited : (33)

References (48)
  • 1
    • 77956585894 scopus 로고    scopus 로고
    • Multipotent mesenchymal stem cell grafting to treat cutaneous radiation syndrome: Development of a new minipig model
    • Agay D, Scherthan H, Forcheron F, Grenier N, Herodin F, et al. (2010) Multipotent mesenchymal stem cell grafting to treat cutaneous radiation syndrome: development of a new minipig model. Exp Hematol 38: 945-956.
    • (2010) Exp Hematol , vol.38 , pp. 945-956
    • Agay, D.1    Scherthan, H.2    Forcheron, F.3    Grenier, N.4    Herodin, F.5
  • 2
    • 70350449672 scopus 로고    scopus 로고
    • Radiation accidents over the last 60 years
    • Nénot J-C (2009) Radiation accidents over the last 60 years. J Radiol Prot 29: 301-320.
    • (2009) J Radiol Prot , vol.29 , pp. 301-320
    • Nénot, J.-C.1
  • 3
    • 36549007486 scopus 로고    scopus 로고
    • Computed tomography - An increasing source of radiation exposure
    • DOI 10.1056/NEJMra072149
    • Brenner DJ, Hall EJ (2007) Computed tomography-an increasing source of radiation exposure. N Engl J Med 357: 2277-2284. (Pubitemid 350190758)
    • (2007) New England Journal of Medicine , vol.357 , Issue.22 , pp. 2277-2284
    • Brenner, D.J.1    Hall, E.J.2
  • 4
    • 80052930413 scopus 로고    scopus 로고
    • Review of retrospective dosimetry techniques for external ionising radiation exposures
    • Ainsbury EA, Bakhanova E, Barquinero JF, Brai M, Chumak V, et al. (2011) Review of retrospective dosimetry techniques for external ionising radiation exposures. Radiat Prot Dosimetry 147: 573-592.
    • (2011) Radiat Prot Dosimetry , vol.147 , pp. 573-592
    • Ainsbury, E.A.1    Bakhanova, E.2    Barquinero, J.F.3    Brai, M.4    Chumak, V.5
  • 5
    • 78649503031 scopus 로고    scopus 로고
    • The use of gamma-H2AX as a biodosimeter for total-body radiation exposure in non-human primates
    • Redon CE, Nakamura AJ, Gouliaeva K, Rahman A, Blakely WF, et al. (2010) The use of gamma-H2AX as a biodosimeter for total-body radiation exposure in non-human primates. PLoS One 5: e15544.
    • (2010) PLoS One , vol.5
    • Redon, C.E.1    Nakamura, A.J.2    Gouliaeva, K.3    Rahman, A.4    Blakely, W.F.5
  • 6
    • 84856833962 scopus 로고    scopus 로고
    • Autologous adipocyte derived stem cells favour healing in a minipig model of cutaneous radiation syndrome
    • Forcheron F, Agay D, Scherthan H, Riccobono D, Herodin F, et al. (2012) Autologous adipocyte derived stem cells favour healing in a minipig model of cutaneous radiation syndrome. PLoS One 7: e31694.
    • (2012) PLoS One , vol.7
    • Forcheron, F.1    Agay, D.2    Scherthan, H.3    Riccobono, D.4    Herodin, F.5
  • 7
    • 77956641199 scopus 로고    scopus 로고
    • Noninvasive radiation burn diagnosis using speckle phenomenon with a fractal approach to processing
    • Carvalho O, Benderitter M, Roy L (2010) Noninvasive radiation burn diagnosis using speckle phenomenon with a fractal approach to processing. J Biomed Opt 15: 027013.
    • (2010) J Biomed Opt , vol.15 , pp. 027013
    • Carvalho, O.1    Benderitter, M.2    Roy, L.3
  • 9
    • 84880152165 scopus 로고    scopus 로고
    • Evaluation of the Gamma-H2AX Assay for Radiation Biodosimetry in a Swine Model
    • Moroni M, Maeda D, Whitnall MH, Bonner WM, Redon CE (2013) Evaluation of the Gamma-H2AX Assay for Radiation Biodosimetry in a Swine Model. Int J Mol Sci 14: 14119-14135.
    • (2013) Int J Mol Sci , vol.14 , pp. 14119-14135
    • Moroni, M.1    Maeda, D.2    Whitnall, M.H.3    Bonner, W.M.4    Redon, C.E.5
  • 11
    • 33646117239 scopus 로고    scopus 로고
    • Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks
    • Bekker-Jensen S, Lukas C, Kitagawa R, Melander F, Kastan MB, et al. (2006) Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks. J Cell Biol 173: 195-206.
    • (2006) J Cell Biol , vol.173 , pp. 195-206
    • Bekker-Jensen, S.1    Lukas, C.2    Kitagawa, R.3    Melander, F.4    Kastan, M.B.5
  • 12
    • 78649445307 scopus 로고    scopus 로고
    • Mre11-Rad50-Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaks
    • Amst
    • Williams GJ, Lees-Miller SP, Tainer JA (2010) Mre11-Rad50-Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaks. DNA Repair (Amst) 9: 1299-1306.
    • (2010) DNA Repair , vol.9 , pp. 1299-1306
    • Williams, G.J.1    Lees-Miller, S.P.2    Tainer, J.A.3
  • 13
    • 0032861343 scopus 로고    scopus 로고
    • Megabase chromatin domains involved in DNA double-strand breaks in vivo
    • Rogakou EP, Boon C, Redon C, Bonner WM (1999) Megabase chromatin domains involved in DNA double-strand breaks in vivo. J Cell Biol 146: 905-916.
    • (1999) J Cell Biol , vol.146 , pp. 905-916
    • Rogakou, E.P.1    Boon, C.2    Redon, C.3    Bonner, W.M.4
  • 15
    • 79952158787 scopus 로고    scopus 로고
    • Adapting the gamma-H2AX assay for automated processing in human lymphocytes. 1. Technological aspects
    • Turner HC, Brenner DJ, Chen Y, Bertucci A, Zhang J, et al. (2011) Adapting the gamma-H2AX assay for automated processing in human lymphocytes. 1. Technological aspects. Radiat Res 175: 282-290.
    • (2011) Radiat Res , vol.175 , pp. 282-290
    • Turner, H.C.1    Brenner, D.J.2    Chen, Y.3    Bertucci, A.4    Zhang, J.5
  • 16
    • 33845606709 scopus 로고    scopus 로고
    • Leukocyte DNA damage after multi-detector row CT: A quantitative biomarker of low-level radiation exposure
    • DOI 10.1148/radiol.2421060171
    • Rothkamm K, Balroop S, Shekhdar J, Fernie P, Goh V (2007) Leukocyte DNA damage after multi-detector row CT: a quantitative biomarker of low-level radiation exposure. Radiology 242: 244-251. (Pubitemid 44956030)
    • (2007) Radiology , vol.242 , Issue.1 , pp. 244-251
    • Rothkamm, K.1    Balroop, S.2    Shekhdar, J.3    Fernie, P.4    Goh, V.5
  • 18
    • 84862998693 scopus 로고    scopus 로고
    • Persistent DNA damage after high dose in vivo gamma exposure of minipig skin
    • Ahmed EA, Agay D, Schrock G, Drouet M, Meineke V, et al. (2012) Persistent DNA damage after high dose in vivo gamma exposure of minipig skin. PLoS One 7: e39521.
    • (2012) PLoS One , vol.7
    • Ahmed, E.A.1    Agay, D.2    Schrock, G.3    Drouet, M.4    Meineke, V.5
  • 19
    • 81855185421 scopus 로고    scopus 로고
    • The impact of individual in vivo repair of DNA double-strand breaks on oral mucositis in adjuvant radiotherapy of head-and-neck cancer
    • Fleckenstein J, Kuhne M, Seegmuller K, Derschang S, Melchior P, et al. (2011) The impact of individual in vivo repair of DNA double-strand breaks on oral mucositis in adjuvant radiotherapy of head-and-neck cancer. Int J Radiat Oncol Biol Phys 81: 1465-1472.
    • (2011) Int J Radiat Oncol Biol Phys , vol.81 , pp. 1465-1472
    • Fleckenstein, J.1    Kuhne, M.2    Seegmuller, K.3    Derschang, S.4    Melchior, P.5
  • 20
    • 72449153474 scopus 로고    scopus 로고
    • gamma-H2AX foci as a biomarker for patient X-ray exposure in pediatric cardiac catheterization: Are we underestimating radiation risks?
    • Beels L, Bacher K, De Wolf D, Werbrouck J, Thierens H (2009) gamma-H2AX foci as a biomarker for patient X-ray exposure in pediatric cardiac catheterization: are we underestimating radiation risks? Circulation 120: 1903-1909.
    • (2009) Circulation , vol.120 , pp. 1903-1909
    • Beels, L.1    Bacher, K.2    De Wolf, D.3    Werbrouck, J.4    Thierens, H.5
  • 21
    • 80053109692 scopus 로고    scopus 로고
    • Gamma-H2AX-based dose estimation for whole and partial body radiation exposure
    • Horn S, Barnard S, Rothkamm K (2011) Gamma-H2AX-based dose estimation for whole and partial body radiation exposure. PLoS One 6: e25113.
    • (2011) PLoS One , vol.6
    • Horn, S.1    Barnard, S.2    Rothkamm, K.3
  • 22
    • 77955158269 scopus 로고    scopus 로고
    • Quantification of gamma-H2AX foci in human lymphocytes: A method for biological dosimetry after ionizing radiation exposure
    • Roch-Lefevre S, Mandina T, Voisin P, Gaetan G, Mesa JE, et al. (2010) Quantification of gamma-H2AX foci in human lymphocytes: a method for biological dosimetry after ionizing radiation exposure. Radiat Res 174: 185-194.
    • (2010) Radiat Res , vol.174 , pp. 185-194
    • Roch-Lefevre, S.1    Mandina, T.2    Voisin, P.3    Gaetan, G.4    Mesa, J.E.5
  • 23
    • 81055124289 scopus 로고    scopus 로고
    • Induction and persistence of radiation-induced DNA damage is more pronounced in young animals than in old animals
    • Albany NY
    • Hudson D, Kovalchuk I, Koturbash I, Kolb B, Martin OA, et al. (2011) Induction and persistence of radiation-induced DNA damage is more pronounced in young animals than in old animals. Aging (Albany NY) 3: 609-620.
    • (2011) Aging , vol.3 , pp. 609-620
    • Hudson, D.1    Kovalchuk, I.2    Koturbash, I.3    Kolb, B.4    Martin, O.A.5
  • 24
    • 80052936247 scopus 로고    scopus 로고
    • Q(gamma-H2AX), an analysis method for partial-body radiation exposure using gamma-H2AX in nonhuman primate lymphocytes
    • Redon CE, Nakamura AJ, Gouliaeva K, Rahman A, Blakely WF, et al. (2011) Q(gamma-H2AX), an analysis method for partial-body radiation exposure using gamma-H2AX in nonhuman primate lymphocytes. Radiat Meas 46: 877-881.
    • (2011) Radiat Meas , vol.46 , pp. 877-881
    • Redon, C.E.1    Nakamura, A.J.2    Gouliaeva, K.3    Rahman, A.4    Blakely, W.F.5
  • 26
    • 0036789173 scopus 로고    scopus 로고
    • Quantitative detection of (125)IdU-induced DNA double-strand breaks with gamma-H2AX antibody
    • Sedelnikova OA, Rogakou EP, Panyutin IG, Bonner WM (2002) Quantitative detection of (125)IdU-induced DNA double-strand breaks with gamma-H2AX antibody. Radiat Res 158: 486-492.
    • (2002) Radiat Res , vol.158 , pp. 486-492
    • Sedelnikova, O.A.1    Rogakou, E.P.2    Panyutin, I.G.3    Bonner, W.M.4
  • 28
    • 22944462083 scopus 로고    scopus 로고
    • Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1
    • DOI 10.1083/jcb.200503043
    • Bekker-Jensen S, Lukas C, Melander F, Bartek J, Lukas J (2005) Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1. J Cell Biol 170: 201-211. (Pubitemid 41043803)
    • (2005) Journal of Cell Biology , vol.170 , Issue.2 , pp. 201-211
    • Bekker-Jensen, S.1    Lukas, C.2    Melander, F.3    Bartek, J.4    Lukas, J.5
  • 29
    • 33646777783 scopus 로고    scopus 로고
    • Genetic dissection of vertebrate 53BP1: A major role in non-homologous end joining of DNA double strand breaks
    • DOI 10.1016/j.dnarep.2006.03.008, PII S1568786406000899
    • Nakamura K, Sakai W, Kawamoto T, Bree RT, Lowndes NF, et al. (2006) Genetic dissection of vertebrate 53BP1: a major role in non-homologous end joining of DNA double strand breaks. DNA Repair (Amst) 5: 741-749. (Pubitemid 43766521)
    • (2006) DNA Repair , vol.5 , Issue.6 , pp. 741-749
    • Nakamura, K.1    Sakai, W.2    Kawamoto, T.3    Bree, R.T.4    Lowndes, N.F.5    Takeda, S.6    Taniguchi, Y.7
  • 31
    • 0030764691 scopus 로고    scopus 로고
    • hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks
    • Maser RS, Monsen KJ, Nelms BE, Petrini JH (1997) hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks. Mol Cell Biol 17: 6087-6096. (Pubitemid 27411117)
    • (1997) Molecular and Cellular Biology , vol.17 , Issue.10 , pp. 6087-6096
    • Maser, R.S.1    Monsen, K.J.2    Nelms, B.E.3    Petrini, J.H.J.4
  • 32
    • 0015626755 scopus 로고
    • Chromosome aberration dosimetry using human lymphocytes in simulated partial body irradiation
    • Lloyd DC, Purrott RJ, Dolphin GW (1973) Chromosome aberration dosimetry using human lymphocytes in simulated partial body irradiation. Phys Med Biol 18: 421-431.
    • (1973) Phys Med Biol , vol.18 , pp. 421-431
    • Lloyd, D.C.1    Purrott, R.J.2    Dolphin, G.W.3
  • 34
    • 77951977394 scopus 로고    scopus 로고
    • Radiation-induced DNA repair foci: Spatio-temporal aspects of formation, application for assessment of radiosensitivity and biological dosimetry
    • Belyaev IY (2010) Radiation-induced DNA repair foci: spatio-temporal aspects of formation, application for assessment of radiosensitivity and biological dosimetry. Mutat Res 704: 132-141.
    • (2010) Mutat Res , vol.704 , pp. 132-141
    • Belyaev, I.Y.1
  • 35
    • 84883476386 scopus 로고    scopus 로고
    • Relative biological efficiency of protons at low and therapeutic doses in induction of 53BP1/gammaH2AX foci in lymphocytes from umbilical cord blood
    • Sorokina S, Markova E, Gursky J, Dobrovodsky J, Belyaev I (2013) Relative biological efficiency of protons at low and therapeutic doses in induction of 53BP1/gammaH2AX foci in lymphocytes from umbilical cord blood. Int J Radiat Biol 89: 716-723.
    • (2013) Int J Radiat Biol , vol.89 , pp. 716-723
    • Sorokina, S.1    Markova, E.2    Gursky, J.3    Dobrovodsky, J.4    Belyaev, I.5
  • 36
    • 33646090171 scopus 로고    scopus 로고
    • DNA-PK phosphorylates histone H2AX during apoptotic DNA fragmentation in mammalian cells
    • Amst
    • Mukherjee B, Kessinger C, Kobayashi J, Chen BP, Chen DJ, et al. (2006) DNA-PK phosphorylates histone H2AX during apoptotic DNA fragmentation in mammalian cells. DNA Repair (Amst) 5: 575-590.
    • (2006) DNA Repair , vol.5 , pp. 575-590
    • Mukherjee, B.1    Kessinger, C.2    Kobayashi, J.3    Chen, B.P.4    Chen, D.J.5
  • 37
    • 80655127835 scopus 로고    scopus 로고
    • Retention of gammaH2AX foci as an indication of lethal DNA damage
    • Olive PL (2011) Retention of gammaH2AX foci as an indication of lethal DNA damage. Radiother Oncol 101: 18-23.
    • (2011) Radiother Oncol , vol.101 , pp. 18-23
    • Olive, P.L.1
  • 38
    • 3242790241 scopus 로고    scopus 로고
    • Gamma-H2AX expression pattern in non-irradiated neonatal mouse germ cells and after low-dose gamma-radiation: Relationships between chromatid breaks and DNA double-strand breaks
    • DOI 10.1095/biolreprod.104.027466
    • Forand A, Dutrillaux B, Bernardino-Sgherri J (2004) Gamma-H2AX expression pattern in non-irradiated neonatal mouse germ cells and after low-dose gamma-radiation: relationships between chromatid breaks and DNA double-strand breaks. Biol Reprod 71: 643-649. (Pubitemid 38970542)
    • (2004) Biology of Reproduction , vol.71 , Issue.2 , pp. 643-649
    • Forand, A.1    Dutrillaux, B.2    Bernardino-Sgherri, J.3
  • 39
    • 34247634029 scopus 로고    scopus 로고
    • Kinetics and dose-response of residual 53BP1/gamma-H2AX foci: Co-localization, relationship with DSB repair and clonogenic survival
    • DOI 10.1080/09553000601170469, PII 777650875
    • Markova E, Schultz N, Belyaev IY (2007) Kinetics and dose-response of residual 53BP1/gamma-H2AX foci: co-localization, relationship with DSB repair and clonogenic survival. Int J Radiat Biol 83: 319-329. (Pubitemid 46676534)
    • (2007) International Journal of Radiation Biology , vol.83 , Issue.5 , pp. 319-329
    • Markova, E.1    Schultz, N.2    Belyaev, I.Y.3
  • 40
    • 12944284713 scopus 로고    scopus 로고
    • In situ detection of a PCR-synthesized human pancentromeric DNA hybridization probe by color pigment immunostaining: Application for dicentric assay automation
    • Kolanko CJ, Pyle MD, Nath J, Prasanna PG, Loats H, et al. (2000) In situ detection of a PCR-synthesized human pancentromeric DNA hybridization probe by color pigment immunostaining: application for dicentric assay automation. Biotech Histochem 75: 91-98. (Pubitemid 30618406)
    • (2000) Biotechnic and Histochemistry , vol.75 , Issue.2 , pp. 91-98
    • Kolanko, R.J.1    Pyle, M.D.2    Nath, J.3    Prasanna, P.G.S.4    Loats, H.5    Blakely, W.F.6
  • 41
    • 75149180035 scopus 로고    scopus 로고
    • Synopsis of partial-body radiation diagnostic biomarkers and medical management of radiation injury workshop
    • Prasanna PG, Blakely WF, Bertho JM, Chute JP, Cohen EP, et al. (2010) Synopsis of partial-body radiation diagnostic biomarkers and medical management of radiation injury workshop. Radiat Res 173: 245-253.
    • (2010) Radiat Res , vol.173 , pp. 245-253
    • Prasanna, P.G.1    Blakely, W.F.2    Bertho, J.M.3    Chute, J.P.4    Cohen, E.P.5
  • 43
    • 0023387510 scopus 로고
    • A collaborative exercise on cytogenetic dosimetry for simulated whole and partial body accidental irradiation
    • Lloyd DC, Edwards AA, Prosser JS, Barjaktarovic N, Brown JK, et al. (1987) A collaborative exercise on cytogenetic dosimetry for simulated whole and partial body accidental irradiation. Mutat Res 179: 197-208.
    • (1987) Mutat Res , vol.179 , pp. 197-208
    • Lloyd, D.C.1    Edwards, A.A.2    Prosser, J.S.3    Barjaktarovic, N.4    Brown, J.K.5
  • 44
    • 0037628777 scopus 로고    scopus 로고
    • Low-dose radiation: Thresholds, bystander effects, and adaptive responses
    • Bonner WM (2003) Low-dose radiation: thresholds, bystander effects, and adaptive responses. Proc Natl Acad Sci U S A 100: 4973-4975.
    • (2003) Proc Natl Acad Sci U S a , vol.100 , pp. 4973-4975
    • Bonner, W.M.1
  • 45
    • 70349987104 scopus 로고    scopus 로고
    • Intercellular communication of cellular stress monitored by gamma-H2AX induction
    • Dickey JS, Baird BJ, Redon CE, Sokolov MV, Sedelnikova OA, et al. (2009) Intercellular communication of cellular stress monitored by gamma-H2AX induction. Carcinogenesis 30: 1686-1695.
    • (2009) Carcinogenesis , vol.30 , pp. 1686-1695
    • Dickey, J.S.1    Baird, B.J.2    Redon, C.E.3    Sokolov, M.V.4    Sedelnikova, O.A.5
  • 46
    • 77956292345 scopus 로고    scopus 로고
    • Dose response and repair kinetics of gamma-H2AX foci induced by in vitro irradiation of whole blood and T-lymphocytes with X- and gamma-radiation
    • Beels L, Werbrouck J, Thierens H (2010) Dose response and repair kinetics of gamma-H2AX foci induced by in vitro irradiation of whole blood and T-lymphocytes with X- and gamma-radiation. Int J Radiat Biol 86: 760-768.
    • (2010) Int J Radiat Biol , vol.86 , pp. 760-768
    • Beels, L.1    Werbrouck, J.2    Thierens, H.3
  • 47
    • 84869046652 scopus 로고    scopus 로고
    • Susceptibility to bystander DNA damage is influenced by replication and transcriptional activity
    • Dickey JS, Baird BJ, Redon CE, Avdoshina V, Palchik G, et al. (2012) Susceptibility to bystander DNA damage is influenced by replication and transcriptional activity. Nucleic Acids Res 40: 10274-10286.
    • (2012) Nucleic Acids Res , vol.40 , pp. 10274-10286
    • Dickey, J.S.1    Baird, B.J.2    Redon, C.E.3    Avdoshina, V.4    Palchik, G.5
  • 48
    • 77956208698 scopus 로고    scopus 로고
    • In vivo formation of gamma-H2AX and 53BP1 DNA repair foci in blood cells after radioiodine therapy of differentiated thyroid cancer
    • Lassmann M, Hanscheid H, Gassen D, Biko J, Meineke V, et al. (2010) In vivo formation of gamma-H2AX and 53BP1 DNA repair foci in blood cells after radioiodine therapy of differentiated thyroid cancer. J Nucl Med 51: 1318-1325.
    • (2010) J Nucl Med , vol.51 , pp. 1318-1325
    • Lassmann, M.1    Hanscheid, H.2    Gassen, D.3    Biko, J.4    Meineke, V.5


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