Intercellular communication of cellular stress monitored by γ-H2AX induction

Carcinogenesis

Volumn 30, Issue 10, 2009, Pages 1686-1695

  Dickey, Jennifer S ^a   Baird, Brandon J ^a   Redon, Christophe E ^a   Sokolov, Mykyta V ^a   Sedelnikova, Olga A ^a   Bonner, William M ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; GAMMA HISTONE H2AX; HISTONE H2AX; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; P53 BINDING PROTEIN 1; REACTIVE OXYGEN METABOLITE; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ARTICLE; BYSTANDER EFFECT; CELL COMMUNICATION; CELL CYCLE S PHASE; CELL STRESS; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; CYTOKINE RELEASE; DOUBLE STRANDED DNA BREAK; FEMALE; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; IONIZING RADIATION; MALE; MALIGNANT TRANSFORMATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN INDUCTION; SENESCENCE; TARGET CELL; TUMOR CELL; ULTRAVIOLET RADIATION;

BREAST; CELL COMMUNICATION; CELL DIVISION; CELL TRANSFORMATION, NEOPLASTIC; DNA, NEOPLASM; ENZYME INHIBITORS; FEMALE; FIBROBLASTS; HELA CELLS; HISTONES; HUMANS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; S PHASE; STRESS, PHYSIOLOGICAL; TRANSFORMING GROWTH FACTOR BETA; ULTRAVIOLET RAYS; UTERINE CERVICAL NEOPLASMS;

EID: 70349987104     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgp192     Document Type: Article

References (51)

1. Nagasawa,H. et al. (1992) Induction of sister chromatid exchanges by extremely low doses of alpha-particles. Cancer Res., 52, 6394-6396.
2. Nagasawa,H. et al. (2002) Bystander effect for chromosomal aberrations induced in wild-type and repair deficient CHO cells by low fluences of alpha particles. Mutat. Res., 508, 121-129.
3. Azzam,E.I. et al. (2002) Oxidative metabolism modulates signal transduction and micronucleus formation in bystander cells from alphaparticle- irradiated normal human fibroblast cultures. Cancer Res., 62, 5436-5442.
4. Prise,K.M. et al. (2006) What role for DNA damage and repair in the bystander response? Mutat. Res., 597, 1-4.
5. Hu,B. et al. (2006) The time and spatial effects of bystander response in mammalian cells induced by low dose radiation. Carcinogenesis, 27, 245-251.
6. Koturbash,I. et al. (2006) Irradiation induces DNA damage and modulates epigenetic effectors in distant bystander tissue in vivo. Oncogene, 25, 4267-4275.
7. Sokolov,M.V. et al. (2005) Ionizing radiation induces DNA doublestrand breaks in bystander primary human fibroblasts. Oncogene 24, 7257-7265.
8. Tartier,L. et al. (2007) Cytoplasmic irradiation induces mitochondrialdependent 53BP1 protein relocalization in irradiated and bystander cells. Cancer Res., 67, 5872-5879.
9. Whiteside,J.R. et al. (2009) A bystander effect is induced in human cells treated with UVA radiation but not UVB radiation. Radiat. Res., 171, 204-211.
10. Bonner,W.M. et al. (2008) gammaH2AX and cancer. Nat. Rev. Cancer, 8, 957-967.
11. Limoli,C.L. et al. (1993) A new method for introducing double-strand breaks into cellular DNA. Radiat. Res., 134, 160-169.
12. Limoli,C.L. et al. (1995) Photochemical production of double-strand breaks in cellular DNA. Mutagenesis, 10, 453-456.
13. Han,W. et al. (2007) Constitutive nitric oxide acting as a possible intercellular signaling molecule in the initiation of radiation-induced DNA double strand breaks in non-irradiated bystander cells. Oncogene, 26, 2330-2339.
14. Rogakou,E.P. et al. (1999) Megabase chromatin domains involved in DNA double-strand breaks in vivo. J. Cell Biol., 146, 905-916.
15. Shimura,T. et al. (2007) DNA-PK is involved in repairing a transient surge of DNA breaks induced by deceleration of DNA replication. J. Mol. Biol., 367, 665-680.
16. Nakamura,A.J. et al. (2008) Both telomeric and non-telomeric DNA damage are determinants of mammalian cellular senescence. Epigenetics Chromatin, 1, 6.
17. Adams,M.M. et al. (2006) Tying the loose ends together in DNA double strand break repair with 53BP1. Cell Div., 1, 19.
18. Kashino,G. et al. (2004) Evidence for induction of DNA double strand breaks in the bystander response to targeted soft X-rays in CHO cells. Mutat. Res., 556, 209-215.
19. Smilenov,L.B. et al. (2006) A microbeam study of DNA double-strand breaks in bystander primary human fibroblasts. Radiat. Prot. Dosimetry, 122, 256-259.
20. Groesser,T. et al. (2008) Lack of bystander effects from high-LET radiation for early cytogenetic end points. Radiat. Res., 170 794-802.
21. Ross,C.K. et al. (2009) Comments on 'Cellular response to modulated radiation fields'. Phys. Med. Biol., 54, L11-L33.
22. Pfeifer,G.P. et al. (2005) Mutations induced by ultraviolet light. Mutat. Res., 571, 19-31.
23. Marti,T.M. et al. (2006) H2AX phosphorylation within the G1 phase after UV irradiation depends on nucleotide excision repair and not DNA double-strand breaks. Proc. Natl Acad. Sci. USA, 103, 9891-9896.
24. Burdak-Rothkamm,S. et al. (2007) ATR-dependent radiation-induced gamma H2AX foci in bystander primary human astrocytes and glioma cells. Oncogene, 26, 993-1002.
25. Moldovan,G.L. et al. (2007) PCNA, the maestro of the replication fork. Cell, 129, 665-679.
26. Hei,T.K. et al. (2008) Mechanism of radiation-induced bystander effects: A unifying model. J. Pharm. Pharmacol., 60, 943-950.
27. Ghandhi,S.A. et al. (2008) Global gene expression analyses of bystander and alpha particle irradiated normal human lung fibroblasts: synchronous and differential responses. BMC Med. Genomics, 1 63.
28. Kashino,G. et al. (2007) Effective suppression of bystander effects by DMSO treatment of irradiated CHO cells. J. Radiat. Res. (Tokyo), 48, 327-333.
29. Azzam,E.I. et al. (2003) Oxidative metabolism, gap junctions and the ionizing radiation-induced bystander effect. Oncogene, 22 7050-7057.
30. Shao,C. et al. (2008) Role of TGF-beta1 and nitric oxide in the bystander response of irradiated glioma cells. Oncogene, 27, 434-440.
31. Keefer,L.K. et al. (1996) "NONOates" (1-substituted diazen-1-ium1, 2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms. Methods Enzymol., 268, 281-293.
32. Downs,J.A. (2007) Chromatin structure and DNA double-strand break responses in cancer progression and therapy. Oncogene, 26, 7765-7772.
33. Patocs,A. et al. (2007) Breast-cancer stromal cells with TP53 mutations and nodal metastases. N. Engl. J. Med., 357, 2543-2551.
34. Fletcher,S.T. et al. (2006) Proteomic analysis of the response of EpiDerm cultures to sodium lauryl sulphate. Toxicol. In Vitro, 20, 975-985.
35. Sedelnikova,O.A. et al. (2007) DNA double-strand breaks form in bystander cells after microbeam irradiation of three-dimensional human tissue models. Cancer Res., 67, 4295-4302.
36. Sokolov,M.V. et al. (2007) gamma-H2AX in bystander cells: Not just a radiation-triggered event, a cellular response to stress mediated by intercellular communication. Cell Cycle, 6, 2210-2212.
37. Dong,K.K. et al. (2008) UV-induced DNA damage initiates release of MMP-1 in human skin. Exp. Dermatol., 17, 1037-1044.
38. Yarosh,D. et al. (2008) UV-induced degradation of collagen I is mediated by soluble factors released from keratinocytes. Photochem. Photobiol., 84, 67-68.
39. Pawelec,G. et al. (2009) Special issue on cancer and ageing. Mech. Ageing Dev., 130, 1-2.
40. Binder,B.R. et al. (2008) The plasminogen activator inhibitor "paradox" in cancer. Immunol. Lett., 118, 116-124.
41. Zhang,Y. et al. (2009) TGFBI deficiency predisposes mice to spontaneous tumor development. Cancer Res., 69, 37-44.
42. Jungst,C. et al. (2004) Oxidative damage is increased in human liver tissue adjacent to hepatocellular carcinoma. Hepatology, 39, 1663-1672.
43. Portess,D.I. et al. (2007) Low-dose irradiation of nontransformed cells stimulates the selective removal of precancerous cells via intercellular induction of apoptosis. Cancer Res., 67, 1246-1253.
44. Coppe,J.P. et al. (2008) Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor. PLoS Biol., 6, 2853-2868.
45. Nagar,S. et al. (2005) The death-inducing effect and genomic instability. Radiat. Res., 163, 316-323.
46. Glaser,R. et al. (2005) Stress-induced immune dysfunction: implications for health. Nat. Rev. Immunol., 5, 243-251.
47. Aggarwal,B.B. et al. (2006) Inflammation and cancer: How hot is the link? Biochem. Pharmacol., 72, 1605-1621.
48. Kultz,D. (2005) Molecular and evolutionary basis of the cellular stress response. Annu. Rev. Physiol., 67, 225-257.
49. Yauk,C. et al. (2008) Germ-line mutations, DNA damage, and global hypermethylation in mice exposed to particulate air pollution in an urban/industrial location. Proc. Natl Acad. Sci. USA, 105, 605-610.
50. Zhou,H. et al. (2005) Mechanism of radiation-induced bystander effect: Role of the cyclooxygenase-2 signaling pathway. Proc. Natl Acad. Sci. USA, 102, 14641-14646.
51. Hei,T.K. (2006) Cyclooxygenase-2 as a signaling molecule in radiation-induced bystander effect. Mol. Carcinog., 45, 455-460.