메뉴 건너뛰기




Volumn 2014, Issue , 2014, Pages

Induction of apoptosis in human multiple myeloma cell lines by ebselen via enhancing the endogenous reactive oxygen species production

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; CYTOCHROME C; EBSELEN; PROTEIN BAX; REACTIVE OXYGEN METABOLITE; ORGANOSELENIUM DERIVATIVE; PYRROLE DERIVATIVE;

EID: 84896842295     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2014/696107     Document Type: Article
Times cited : (39)

References (54)
  • 1
    • 0021185122 scopus 로고
    • A novel biologically active seleno-organic compound - I. Glutathione peroxidase-like activity in vitro and antioxidant capacity of PZ 51 (Ebselen)
    • 2-s2.0-0021185122 10.1016/0006-2952(84)90083-2
    • Muller A., Cadenas E., Graf P., Sies H., A novel biologically active seleno-organic compound-I. Glutathione peroxidase-like activity in vitro and antioxidant capacity of PZ 51 (Ebselen). Biochemical Pharmacology 1984 33 20 3235 3239 2-s2.0-0021185122 10.1016/0006-2952(84)90083-2
    • (1984) Biochemical Pharmacology , vol.33 , Issue.20 , pp. 3235-3239
    • Muller, A.1    Cadenas, E.2    Graf, P.3    Sies, H.4
  • 2
    • 78650042004 scopus 로고    scopus 로고
    • Antiatherosclerotic and renoprotective effects of ebselen in the diabetic apolipoprotein E/GPx1-double knockout mouse
    • 2-s2.0-78650042004 10.2337/db10-0195
    • Chew P., Yuen D. Y. C., Stefanovic N., Pete J., Coughlan M. T., Jandeleit-Dahm K. A., Thomas M. C., Rosenfeldt F., Cooper M. E., de Haan J. B., Antiatherosclerotic and renoprotective effects of ebselen in the diabetic apolipoprotein E/GPx1-double knockout mouse. Diabetes 2010 59 12 3198 3207 2-s2.0-78650042004 10.2337/db10-0195
    • (2010) Diabetes , vol.59 , Issue.12 , pp. 3198-3207
    • Chew, P.1    Yuen, D.Y.C.2    Stefanovic, N.3    Pete, J.4    Coughlan, M.T.5    Jandeleit-Dahm, K.A.6    Thomas, M.C.7    Rosenfeldt, F.8    Cooper, M.E.9    De Haan, J.B.10
  • 3
    • 84883576945 scopus 로고    scopus 로고
    • Effects of ebselen on radiocontrast media-induced hepatotoxicity in rats
    • 10.1177/0748233712442730
    • Basarslan F., Yilmaz N., Davarci I., Effects of ebselen on radiocontrast media-induced hepatotoxicity in rats. Toxicology and Industrial Health 2013 29 8 746 752 10.1177/0748233712442730
    • (2013) Toxicology and Industrial Health , vol.29 , Issue.8 , pp. 746-752
    • Basarslan, F.1    Yilmaz, N.2    Davarci, I.3
  • 4
    • 79953700850 scopus 로고    scopus 로고
    • Effects of prevention of oxidative and nitro-oxidative stress on experimental rat colon anastomosis using acetylcysteine, ebselen and 1400w
    • 2-s2.0-79953700850
    • Poyrazoglu Y., Yigit T., Harlak A., Mentes O., Gorgulu S., Uzar A. I., Kozak O., Effects of prevention of oxidative and nitro-oxidative stress on experimental rat colon anastomosis using acetylcysteine, ebselen and 1400w. Acta Chirurgica Belgica 2011 111 1 26 31 2-s2.0-79953700850
    • (2011) Acta Chirurgica Belgica , vol.111 , Issue.1 , pp. 26-31
    • Poyrazoglu, Y.1    Yigit, T.2    Harlak, A.3    Mentes, O.4    Gorgulu, S.5    Uzar, A.I.6    Kozak, O.7
  • 5
    • 67650932715 scopus 로고    scopus 로고
    • Erdosteine and ebselen as useful agents in intestinal ischemia/reperfusion injury
    • 2-s2.0-67650932715 10.1016/j.jss.2008.06.017
    • Tunc T., Uysal B., Atabek C., Kesik V., Caliskan B., Oztas E., Ersoz N., Oter S., Guven A., Erdosteine and ebselen as useful agents in intestinal ischemia/reperfusion injury. Journal of Surgical Research 2009 155 2 210 216 2-s2.0-67650932715 10.1016/j.jss.2008.06.017
    • (2009) Journal of Surgical Research , vol.155 , Issue.2 , pp. 210-216
    • Tunc, T.1    Uysal, B.2    Atabek, C.3    Kesik, V.4    Caliskan, B.5    Oztas, E.6    Ersoz, N.7    Oter, S.8    Guven, A.9
  • 7
    • 84984568910 scopus 로고    scopus 로고
    • Methylmercury-induced alterations in astrocyte functions are attenuated by ebselen
    • 2-s2.0-79952204260 10.1016/j.neuro.2011.01.004
    • Yin Z., Lee E., Ni M., Jiang H., Milatovic D., Rongzhu L., Farina M., Rocha J. B. T., Aschner M., Methylmercury-induced alterations in astrocyte functions are attenuated by ebselen. NeuroToxicology 2011 32 3 291 299 2-s2.0-79952204260 10.1016/j.neuro.2011.01.004
    • (2011) NeuroToxicology , vol.32 , Issue.3 , pp. 291-299
    • Yin, Z.1    Lee, E.2    Ni, M.3    Jiang, H.4    Milatovic, D.5    Rongzhu, L.6    Farina, M.7    Rocha, J.B.T.8    Aschner, M.9
  • 8
    • 79957969635 scopus 로고    scopus 로고
    • Neuroprotective effects of ebselen following forebrain ischemia: Involvement of glutamate and nitric oxide
    • 2-s2.0-79957969635 10.2176/nmc.51.337
    • Koizumi H., Fujisawa H., Suehiro E., Shirao S., Suzuki M., Neuroprotective effects of ebselen following forebrain ischemia: involvement of glutamate and nitric oxide. Neurologia Medico-Chirurgica 2011 51 5 337 343 2-s2.0-79957969635 10.2176/nmc.51.337
    • (2011) Neurologia Medico-Chirurgica , vol.51 , Issue.5 , pp. 337-343
    • Koizumi, H.1    Fujisawa, H.2    Suehiro, E.3    Shirao, S.4    Suzuki, M.5
  • 10
    • 72649091301 scopus 로고    scopus 로고
    • Metabolism of selenium compounds catalyzed by the mammalian selenoprotein thioredoxin reductase
    • 2-s2.0-72649091301 10.1016/j.bbagen.2009.04.013
    • Lu J., Berndt C., Holmgren A., Metabolism of selenium compounds catalyzed by the mammalian selenoprotein thioredoxin reductase. Biochimica et Biophysica Acta 2009 1790 11 1513 1519 2-s2.0-72649091301 10.1016/j.bbagen.2009.04.013
    • (2009) Biochimica et Biophysica Acta , vol.1790 , Issue.11 , pp. 1513-1519
    • Lu, J.1    Berndt, C.2    Holmgren, A.3
  • 11
    • 0037131424 scopus 로고    scopus 로고
    • A novel antioxidant mechanism of ebselen involving ebselen diselenide, a substrate of mammalian thioredoxin and thioredoxin reductase
    • 2-s2.0-0037131424 10.1074/jbc.M206452200
    • Zhao R., Holmgren A., A novel antioxidant mechanism of ebselen involving ebselen diselenide, a substrate of mammalian thioredoxin and thioredoxin reductase. Journal of Biological Chemistry 2002 277 42 39456 39462 2-s2.0-0037131424 10.1074/jbc.M206452200
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.42 , pp. 39456-39462
    • Zhao, R.1    Holmgren, A.2
  • 12
    • 0023832899 scopus 로고
    • A novel biologically active selenoorganic compound-VII. Biotransformation of ebselen in perfused rat liver
    • 2-s2.0-0023832899
    • Muller A., Gabriel H., Sies H., Terlinden R., Fischer H., Romer A., A novel biologically active selenoorganic compound-VII. Biotransformation of ebselen in perfused rat liver. Biochemical Pharmacology 1988 37 6 1103 1109 2-s2.0-0023832899
    • (1988) Biochemical Pharmacology , vol.37 , Issue.6 , pp. 1103-1109
    • Muller, A.1    Gabriel, H.2    Sies, H.3    Terlinden, R.4    Fischer, H.5    Romer, A.6
  • 13
    • 33744478633 scopus 로고    scopus 로고
    • Ebselen induced C6 glioma cell death in oxygen and glucose deprivation
    • 2-s2.0-33744478633 10.1021/tx0502544
    • Shi H., Liu S., Miyake M., Liu K. J., Ebselen induced C6 glioma cell death in oxygen and glucose deprivation. Chemical Research in Toxicology 2006 19 5 655 660 2-s2.0-33744478633 10.1021/tx0502544
    • (2006) Chemical Research in Toxicology , vol.19 , Issue.5 , pp. 655-660
    • Shi, H.1    Liu, S.2    Miyake, M.3    Liu, K.J.4
  • 14
    • 0031425497 scopus 로고    scopus 로고
    • Diaryl chalcogenides as selective inhibitors of thioredoxin reductase and potential antitumor agents
    • 2-s2.0-0031425497
    • Engman L., Cotgreave I., Angulo M., Taylor C. W., Paine-Murrieta G. D., Powis G., Diaryl chalcogenides as selective inhibitors of thioredoxin reductase and potential antitumor agents. Anticancer Research 1997 17 6 4599 4605 2-s2.0-0031425497
    • (1997) Anticancer Research , vol.17 , Issue.6 , pp. 4599-4605
    • Engman, L.1    Cotgreave, I.2    Angulo, M.3    Taylor, C.W.4    Paine-Murrieta, G.D.5    Powis, G.6
  • 15
    • 0034652202 scopus 로고    scopus 로고
    • Ebselen induces apoptosis in HepG2 cells through rapid depletion of intracellular thiols
    • 2-s2.0-0034652202 10.1006/abbi.1999.1574
    • Yang C.-F., Shen H.-M., Ong C.-N., Ebselen induces apoptosis in HepG2 cells through rapid depletion of intracellular thiols. Archives of Biochemistry and Biophysics 2000 374 2 142 152 2-s2.0-0034652202 10.1006/abbi.1999.1574
    • (2000) Archives of Biochemistry and Biophysics , vol.374 , Issue.2 , pp. 142-152
    • Yang, C.-F.1    Shen, H.-M.2    Ong, C.-N.3
  • 16
    • 0344490255 scopus 로고    scopus 로고
    • Induction of cellular necrosis by the glutathione peroxidase mimetic ebselen
    • 2-s2.0-0344490255 10.1002/jcb.10500
    • Guérin P. J., Gauthier E. R., Induction of cellular necrosis by the glutathione peroxidase mimetic ebselen. Journal of Cellular Biochemistry 2003 89 1 203 211 2-s2.0-0344490255 10.1002/jcb.10500
    • (2003) Journal of Cellular Biochemistry , vol.89 , Issue.1 , pp. 203-211
    • Guérin, P.J.1    Gauthier, E.R.2
  • 17
    • 64849113485 scopus 로고    scopus 로고
    • Control of mitochondrial apoptosis by the Bcl-2 family
    • 2-s2.0-64849113485 10.1242/jcs.031682
    • Brunelle J. K., Letai A., Control of mitochondrial apoptosis by the Bcl-2 family. Journal of Cell Science 2009 122 part 4 437 441 2-s2.0-64849113485 10.1242/jcs.031682
    • (2009) Journal of Cell Science , vol.122 , Issue.PART 4 , pp. 437-441
    • Brunelle, J.K.1    Letai, A.2
  • 18
    • 0026560861 scopus 로고
    • Reduction in apoptosis relative to mitosis in histologically normal epithelium accompanies fibrocystic change and carcinoma of the premenopausal human breast
    • 2-s2.0-0026560861 10.1002/path.1711670106
    • Allan D. J., Howell A., Roberts S. A., Williams G. T., Watson R. J., Coyne J. D., Clarke R. B., Laidlaw I. J., Potten C. S., Reduction in apoptosis relative to mitosis in histologically normal epithelium accompanies fibrocystic change and carcinoma of the premenopausal human breast. Journal of Pathology 1992 167 1 25 32 2-s2.0-0026560861 10.1002/path.1711670106
    • (1992) Journal of Pathology , vol.167 , Issue.1 , pp. 25-32
    • Allan, D.J.1    Howell, A.2    Roberts, S.A.3    Williams, G.T.4    Watson, R.J.5    Coyne, J.D.6    Clarke, R.B.7    Laidlaw, I.J.8    Potten, C.S.9
  • 19
    • 0034468736 scopus 로고    scopus 로고
    • Role of reactive oxygen species (ROS) in apoptosis induction
    • 2-s2.0-0034468736 10.1023/A:1009616228304
    • Simon H.-U., Haj-Yehia A., Levi-Schaffer F., Role of reactive oxygen species (ROS) in apoptosis induction. Apoptosis 2000 5 5 415 418 2-s2.0-0034468736 10.1023/A:1009616228304
    • (2000) Apoptosis , vol.5 , Issue.5 , pp. 415-418
    • Simon, H.-U.1    Haj-Yehia, A.2    Levi-Schaffer, F.3
  • 20
    • 0348049803 scopus 로고    scopus 로고
    • Reactive oxygen species in oncogenic transformation
    • 2-s2.0-0348049803
    • Behrend L., Henderson G., Zwacka R. M., Reactive oxygen species in oncogenic transformation. Biochemical Society Transactions 2003 31 part 6 1441 1444 2-s2.0-0348049803
    • (2003) Biochemical Society Transactions , vol.31 , Issue.PART 6 , pp. 1441-1444
    • Behrend, L.1    Henderson, G.2    Zwacka, R.M.3
  • 21
    • 0028900690 scopus 로고
    • Persistent oxidative stress in cancer
    • 2-s2.0-0028900690 10.1016/0014-5793(94)01368-B
    • Toyokuni S., Persistent oxidative stress in cancer. FEBS Letters 1995 358 1 1 3 2-s2.0-0028900690 10.1016/0014-5793(94)01368-B
    • (1995) FEBS Letters , vol.358 , Issue.1 , pp. 1-3
    • Toyokuni, S.1
  • 22
    • 33847109840 scopus 로고    scopus 로고
    • Reactive oxygen species and p38 mitogen-activated protein kinase activate bax to induce mitochondrial cytochrome c release and apoptosis in response to malonate
    • 2-s2.0-33847109840 10.1124/mol.106.030718
    • Gomez-Lazaro M., Galindo M. F., Melero-Fernandez De Mera R. M., Fernandez-Gómez F. J., Concannon C. G., Segura M. F., Comella J. X., Prehn J. H. M., Jordan J., Reactive oxygen species and p38 mitogen-activated protein kinase activate bax to induce mitochondrial cytochrome c release and apoptosis in response to malonate. Molecular Pharmacology 2007 71 3 736 743 2-s2.0-33847109840 10.1124/mol.106.030718
    • (2007) Molecular Pharmacology , vol.71 , Issue.3 , pp. 736-743
    • Gomez-Lazaro, M.1    Galindo, M.F.2    Melero-Fernandez De Mera, R.M.3    Fernandez-Gómez, F.J.4    Concannon, C.G.5    Segura, M.F.6    Comella, J.X.7    Prehn, J.H.M.8    Jordan, J.9
  • 23
    • 78649713701 scopus 로고    scopus 로고
    • Multiple myeloma: Biology of the disease
    • 2-s2.0-78649713701 10.1016/S0268-960X(10)70003-5
    • Mahindra A., Hideshima T., Anderson K. C., Multiple myeloma: biology of the disease. Blood Reviews 2010 24 supplement 1 S5 S11 2-s2.0-78649713701 10.1016/S0268-960X(10)70003-5
    • (2010) Blood Reviews , vol.24 , Issue.SUPPL. 1
    • Mahindra, A.1    Hideshima, T.2    Anderson, K.C.3
  • 24
    • 8444225024 scopus 로고    scopus 로고
    • NIH molecular libraries initiative
    • 2-s2.0-8444225024 10.1126/science.1105511
    • Austin C. P., Brady L. S., Insel T. R., Collins F. S., NIH molecular libraries initiative. Science 2004 306 5699 1138 1139 2-s2.0-8444225024 10.1126/science.1105511
    • (2004) Science , vol.306 , Issue.5699 , pp. 1138-1139
    • Austin, C.P.1    Brady, L.S.2    Insel, T.R.3    Collins, F.S.4
  • 25
    • 84984578824 scopus 로고    scopus 로고
    • Potential renal and hepatic toxicity of diphenyl diselenide, diphenyl ditelluride and ebselen for rats and mice
    • 2-s2.0-0037420886 10.1016/S0378-4274(03)00090-0
    • Meotti F. C., Borges V. C., Zeni G., Rocha J. B. T., Nogueira C. W., Potential renal and hepatic toxicity of diphenyl diselenide, diphenyl ditelluride and ebselen for rats and mice. Toxicology Letters 2003 143 1 9 16 2-s2.0-0037420886 10.1016/S0378-4274(03)00090-0
    • (2003) Toxicology Letters , vol.143 , Issue.1 , pp. 9-16
    • Meotti, F.C.1    Borges, V.C.2    Zeni, G.3    Rocha, J.B.T.4    Nogueira, C.W.5
  • 26
    • 0031963836 scopus 로고    scopus 로고
    • Ebselen in acute ischemic stroke: A placebo-controlled, double-blind clinical trial
    • 2-s2.0-0031963836
    • Yamaguchi T., Sano K., Takakura K., Saito I., Shinohara Y., Asano T., Yasuhara H., Ebselen in acute ischemic stroke: a placebo-controlled, double-blind clinical trial. Stroke 1998 29 1 12 17 2-s2.0-0031963836
    • (1998) Stroke , vol.29 , Issue.1 , pp. 12-17
    • Yamaguchi, T.1    Sano, K.2    Takakura, K.3    Saito, I.4    Shinohara, Y.5    Asano, T.6    Yasuhara, H.7
  • 27
    • 84865266098 scopus 로고    scopus 로고
    • The protective effect of ebselen on radiocontrast-induced nephrotoxicity
    • 10.3109/0886022X.2012.706880
    • Ozgur T., Tutanc M., Zararsiz I., The protective effect of ebselen on radiocontrast-induced nephrotoxicity. Renal Failure 2012 34 8 991 997 10.3109/0886022X.2012.706880
    • (2012) Renal Failure , vol.34 , Issue.8 , pp. 991-997
    • Ozgur, T.1    Tutanc, M.2    Zararsiz, I.3
  • 28
    • 51649089169 scopus 로고    scopus 로고
    • Ebselen sensitizes glioblastoma cells to Tumor Necrosis Factor (TNF α)-induced apoptosis through two distinct pathways involving NF- B downregulation and Fas-mediated formation of death inducing signaling complex
    • 2-s2.0-51649089169 10.1002/ijc.23771
    • Sharma V., Tewari R., Sk U. H., Joseph C., Sen E., Ebselen sensitizes glioblastoma cells to Tumor Necrosis Factor (TNF α)-induced apoptosis through two distinct pathways involving NF- B downregulation and Fas-mediated formation of death inducing signaling complex. International Journal of Cancer 2008 123 9 2204 2212 2-s2.0-51649089169 10.1002/ijc.23771
    • (2008) International Journal of Cancer , vol.123 , Issue.9 , pp. 2204-2212
    • Sharma, V.1    Tewari, R.2    Sk, U.H.3    Joseph, C.4    Sen, E.5
  • 29
    • 58049114757 scopus 로고    scopus 로고
    • Induction of apoptosis in a human leukemic cell line via reactive oxygen species modulation by antioxidants
    • 2-s2.0-58049114757 10.1016/j.freeradbiomed.2008.10.027
    • Maraldi T., Prata C., Fiorentini D., Zambonin L., Landi L., Hakim G., Induction of apoptosis in a human leukemic cell line via reactive oxygen species modulation by antioxidants. Free Radical Biology and Medicine 2009 46 2 244 252 2-s2.0-58049114757 10.1016/j.freeradbiomed.2008.10.027
    • (2009) Free Radical Biology and Medicine , vol.46 , Issue.2 , pp. 244-252
    • Maraldi, T.1    Prata, C.2    Fiorentini, D.3    Zambonin, L.4    Landi, L.5    Hakim, G.6
  • 30
    • 84983721056 scopus 로고    scopus 로고
    • Mitochondrial electron transfer chain complexes inhibition by different organochalcogens
    • 10.1016/j.tiv.2012.10.011
    • Puntel R. L., Roos D. H., Seeger R. L., Mitochondrial electron transfer chain complexes inhibition by different organochalcogens. Toxicology in Vitro 2013 27 1 59 70 10.1016/j.tiv.2012.10.011
    • (2013) Toxicology in Vitro , vol.27 , Issue.1 , pp. 59-70
    • Puntel, R.L.1    Roos, D.H.2    Seeger, R.L.3
  • 31
    • 84984589049 scopus 로고    scopus 로고
    • Organochalcogens inhibit mitochondrial complexes i and II in rat brain: Possible implications for neurotoxicity
    • 10.1007/s12640-012-9365-0
    • Puntel R. L., Roos D. H., Seeger R. L., Organochalcogens inhibit mitochondrial complexes I and II in rat brain: possible implications for neurotoxicity. Neurotoxicity Research 2013 24 2 109 118 10.1007/s12640-012-9365- 0
    • (2013) Neurotoxicity Research , vol.24 , Issue.2 , pp. 109-118
    • Puntel, R.L.1    Roos, D.H.2    Seeger, R.L.3
  • 32
    • 84984582331 scopus 로고    scopus 로고
    • Mitochondrial dysfunction induced by different organochalchogens is mediated by thiol oxidation and is not dependent of the classical mitochondrial permeability transition pore opening
    • 2-s2.0-77955861745 10.1093/toxsci/kfq185
    • Puntel R. L., Roos D. H., Folmer V., Nogueira C. W., Galina A., Aschner M., Rocha J. B. T., Mitochondrial dysfunction induced by different organochalchogens is mediated by thiol oxidation and is not dependent of the classical mitochondrial permeability transition pore opening. Toxicological Sciences 2010 117 1 133 143 2-s2.0-77955861745 10.1093/toxsci/kfq185
    • (2010) Toxicological Sciences , vol.117 , Issue.1 , pp. 133-143
    • Puntel, R.L.1    Roos, D.H.2    Folmer, V.3    Nogueira, C.W.4    Galina, A.5    Aschner, M.6    Rocha, J.B.T.7
  • 33
    • 0037172997 scopus 로고    scopus 로고
    • Ebselen: A substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant
    • 2-s2.0-0037172997 10.1073/pnas.122061399
    • Zhao R., Masayasu H., Holmgren A., Ebselen: a substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant. Proceedings of the National Academy of Sciences of the United States of America 2002 99 13 8579 8584 2-s2.0-0037172997 10.1073/pnas.122061399
    • (2002) Proceedings of the National Academy of Sciences of the United States of America , vol.99 , Issue.13 , pp. 8579-8584
    • Zhao, R.1    Masayasu, H.2    Holmgren, A.3
  • 34
    • 0038730947 scopus 로고    scopus 로고
    • Dual effect of ebselen on mitochondrial permeability transition
    • 2-s2.0-0038730947 10.1016/S0006-2952(03)00114-X
    • Morin D., Zini R., Ligeret H., Neckameyer W., Labidalle S., Tillement J.-P., Dual effect of ebselen on mitochondrial permeability transition. Biochemical Pharmacology 2003 65 10 1643 1651 2-s2.0-0038730947 10.1016/S0006-2952(03)00114-X
    • (2003) Biochemical Pharmacology , vol.65 , Issue.10 , pp. 1643-1651
    • Morin, D.1    Zini, R.2    Ligeret, H.3    Neckameyer, W.4    Labidalle, S.5    Tillement, J.-P.6
  • 35
    • 45849112182 scopus 로고    scopus 로고
    • Bcl-XL inhibits membrane permeabilization by competing with Bax
    • ARTICLE E147 2-s2.0-53049102176 10.1371/journal.pbio.0060147
    • Billen L. P., Kokoski C. L., Lovell J. F., Leber B., Andrews D. W., Bcl-XL inhibits membrane permeabilization by competing with Bax. PLoS Biology 2008 6 6, article e147 2-s2.0-53049102176 10.1371/journal.pbio.0060147
    • (2008) PLoS Biology , vol.6 , Issue.6
    • Billen, L.P.1    Kokoski, C.L.2    Lovell, J.F.3    Leber, B.4    Andrews, D.W.5
  • 36
    • 0035890085 scopus 로고    scopus 로고
    • The expanding role of mitochondria in apoptosis
    • 2-s2.0-0035890085
    • Wang X., The expanding role of mitochondria in apoptosis. Genes and Development 2001 15 22 2922 2933 2-s2.0-0035890085
    • (2001) Genes and Development , vol.15 , Issue.22 , pp. 2922-2933
    • Wang, X.1
  • 37
    • 81255130972 scopus 로고    scopus 로고
    • Modeling the mechanism of the glutathione peroxidase mimic ebselen
    • 2-s2.0-81255130972 10.1021/ic201603v
    • Antony S., Bayse C. A., Modeling the mechanism of the glutathione peroxidase mimic ebselen. Inorganic Chemistry 2011 50 23 12075 12084 2-s2.0-81255130972 10.1021/ic201603v
    • (2011) Inorganic Chemistry , vol.50 , Issue.23 , pp. 12075-12084
    • Antony, S.1    Bayse, C.A.2
  • 38
    • 56749091434 scopus 로고    scopus 로고
    • Antioxidant activity of the anti-inflammatory compound ebselen: A reversible cyclization pathway via selenenic and seleninic acid intermediates
    • 2-s2.0-56749091434 10.1002/chem.200801258
    • Sarma B. K., Mugesh G., Antioxidant activity of the anti-inflammatory compound ebselen: a reversible cyclization pathway via selenenic and seleninic acid intermediates. Chemistry 2008 14 34 10603 10614 2-s2.0-56749091434 10.1002/chem.200801258
    • (2008) Chemistry , vol.14 , Issue.34 , pp. 10603-10614
    • Sarma, B.K.1    Mugesh, G.2
  • 39
    • 84984580672 scopus 로고    scopus 로고
    • Toxicology and pharmacology of selenium: Emphasis on synthetic organoselenium compounds
    • 2-s2.0-80755153273 10.1007/s00204-011-0720-3
    • Nogueira C. W., Rocha J. B. T., Toxicology and pharmacology of selenium: emphasis on synthetic organoselenium compounds. Archives of Toxicology 2011 85 11 1313 1359 2-s2.0-80755153273 10.1007/s00204-011-0720-3
    • (2011) Archives of Toxicology , vol.85 , Issue.11 , pp. 1313-1359
    • Nogueira, C.W.1    Rocha, J.B.T.2
  • 40
    • 0033655899 scopus 로고    scopus 로고
    • Thiol-based antioxidants
    • 2-s2.0-0033655899 10.1016/S0070-2137(01)80007-8
    • Deneke S. M., Thiol-based antioxidants. Current Topics in Cellular Regulation 2001 36 151 180 2-s2.0-0033655899 10.1016/S0070-2137(01)80007-8
    • (2001) Current Topics in Cellular Regulation , vol.36 , pp. 151-180
    • Deneke, S.M.1
  • 41
    • 84983721056 scopus 로고    scopus 로고
    • Mitochondrial electron transfer chain complexes inhibition by different organochalcogens
    • 10.1016/j.tiv.2012.10.011
    • Puntel R. L., Roos D. H., Seeger R. L., Rocha J. B.T., Mitochondrial electron transfer chain complexes inhibition by different organochalcogens. Toxicology in Vitro 2013 27 1 59 70 10.1016/j.tiv.2012.10.011
    • (2013) Toxicology in Vitro , vol.27 , Issue.1 , pp. 59-70
    • Puntel, R.L.1    Roos, D.H.2    Seeger, R.L.3    Rocha, J.B.T.4
  • 42
    • 33847349283 scopus 로고    scopus 로고
    • Reactive oxygen species: A breath of life or death?
    • 2-s2.0-33847349283 10.1158/1078-0432.CCR-06-2082
    • Fruehauf J. P., Meyskens F. L. Jr., Reactive oxygen species: a breath of life or death? Clinical Cancer Research 2007 13 3 789 794 2-s2.0-33847349283 10.1158/1078-0432.CCR-06-2082
    • (2007) Clinical Cancer Research , vol.13 , Issue.3 , pp. 789-794
    • Fruehauf, J.P.1    Meyskens Jr., F.L.2
  • 43
    • 33748165596 scopus 로고    scopus 로고
    • Reactive oxygen species in cancer cells: Live by the sword, die by the sword
    • 2-s2.0-33748165596 10.1016/j.ccr.2006.08.015
    • Schumacker P. T., Reactive oxygen species in cancer cells: live by the sword, die by the sword. Cancer Cell 2006 10 3 175 176 2-s2.0-33748165596 10.1016/j.ccr.2006.08.015
    • (2006) Cancer Cell , vol.10 , Issue.3 , pp. 175-176
    • Schumacker, P.T.1
  • 45
    • 13844266756 scopus 로고    scopus 로고
    • Reduction of acute cisplatin ototoxicity and nephrotoxicity in rats by oral administration of allopurinol and ebselen
    • 2-s2.0-13844266756 10.1016/j.heares.2004.08.002
    • Lynch E. D., Gu R., Pierce C., Kil J., Reduction of acute cisplatin ototoxicity and nephrotoxicity in rats by oral administration of allopurinol and ebselen. Hearing Research 2005 201 1-2 81 89 2-s2.0-13844266756 10.1016/j.heares.2004.08.002
    • (2005) Hearing Research , vol.201 , Issue.1-2 , pp. 81-89
    • Lynch, E.D.1    Gu, R.2    Pierce, C.3    Kil, J.4
  • 46
    • 0037188445 scopus 로고    scopus 로고
    • The effects of ebselen on cisplatin and diethyldithiocarbamate (DDC) cytotoxicity in rat hippocampal astrocytes
    • 2-s2.0-0037188445 10.1016/S0378-4274(02)00056-5
    • Hardej D., Trombetta L. D., The effects of ebselen on cisplatin and diethyldithiocarbamate (DDC) cytotoxicity in rat hippocampal astrocytes. Toxicology Letters 2002 131 3 215 226 2-s2.0-0037188445 10.1016/S0378-4274(02) 00056-5
    • (2002) Toxicology Letters , vol.131 , Issue.3 , pp. 215-226
    • Hardej, D.1    Trombetta, L.D.2
  • 48
    • 0031912696 scopus 로고    scopus 로고
    • Protection by ebselen against cisplatin-induced nephrotoxicity: Antioxidant system
    • 2-s2.0-0031912696 10.1023/A:1006889427520
    • Husain K., Morris C., Whitworth C., Trammell G. L., Rybak L. P., Somani S. M., Protection by ebselen against cisplatin-induced nephrotoxicity: antioxidant system. Molecular and Cellular Biochemistry 1998 178 1-2 127 133 2-s2.0-0031912696 10.1023/A:1006889427520
    • (1998) Molecular and Cellular Biochemistry , vol.178 , Issue.1-2 , pp. 127-133
    • Husain, K.1    Morris, C.2    Whitworth, C.3    Trammell, G.L.4    Rybak, L.P.5    Somani, S.M.6
  • 49
    • 0026716075 scopus 로고
    • The influence of ebselen on the toxicity of cisplatin in LLC-PK1 cells
    • 2-s2.0-0026716075 10.1016/0006-2952(92)90024-D
    • Baldew G. S., Boymans A. P., Mol J. G. J., Vermeulen N. P. E., The influence of ebselen on the toxicity of cisplatin in LLC-PK1 cells. Biochemical Pharmacology 1992 44 2 382 387 2-s2.0-0026716075 10.1016/0006-2952(92)90024-D
    • (1992) Biochemical Pharmacology , vol.44 , Issue.2 , pp. 382-387
    • Baldew, G.S.1    Boymans, A.P.2    Mol, J.G.J.3    Vermeulen, N.P.E.4
  • 50
    • 0025049004 scopus 로고
    • Selective reduction of cis-diamminedichloroplatinum(II) nephrotoxicity by ebselen
    • 2-s2.0-0025049004
    • Baldew G. S., McVie J. G., van der Valk M. A., Los G., de Goeij J. J. M., Vermeulen N. P. E., Selective reduction of cis-diamminedichloroplatinum(II) nephrotoxicity by ebselen. Cancer Research 1990 50 21 7031 7036 2-s2.0-0025049004
    • (1990) Cancer Research , vol.50 , Issue.21 , pp. 7031-7036
    • Baldew, G.S.1    McVie, J.G.2    Van Der Valk, M.A.3    Los, G.4    De Goeij, J.J.M.5    Vermeulen, N.P.E.6
  • 51
    • 33751372282 scopus 로고    scopus 로고
    • Cardioprotective effects of subcutaneous ebselen against daunorubicin-induced cardiomyopathy in rats
    • 2-s2.0-33751372282 10.1111/j.1742-7843.2006.pto-523.x
    • Saad S. Y., Najjar T. A., Arafah M. M., Cardioprotective effects of subcutaneous ebselen against daunorubicin-induced cardiomyopathy in rats. Basic and Clinical Pharmacology and Toxicology 2006 99 6 412 417 2-s2.0-33751372282 10.1111/j.1742-7843.2006.pto-523.x
    • (2006) Basic and Clinical Pharmacology and Toxicology , vol.99 , Issue.6 , pp. 412-417
    • Saad, S.Y.1    Najjar, T.A.2    Arafah, M.M.3
  • 52
    • 57649238084 scopus 로고    scopus 로고
    • Ebselen attenuates cyclophosphamide-induced oxidative stress and DNA damage in mice
    • 2-s2.0-57649238084 10.1080/10715760802566558
    • Tripathi D. N., Jena G. B., Ebselen attenuates cyclophosphamide-induced oxidative stress and DNA damage in mice. Free Radical Research 2008 42 11-12 966 977 2-s2.0-57649238084 10.1080/10715760802566558
    • (2008) Free Radical Research , vol.42 , Issue.11-12 , pp. 966-977
    • Tripathi, D.N.1    Jena, G.B.2
  • 53
    • 0034721770 scopus 로고    scopus 로고
    • Doxorubicin-induced apoptosis in endothelial cells and cardiomyocytes is ameliorated by nitrone spin traps and ebselen. Role of reactive oxygen and nitrogen species
    • 2-s2.0-0034721770 10.1074/jbc.M003890200
    • Kotamraju S., Konorev E. A., Joseph J., Kalyanaraman B., Doxorubicin-induced apoptosis in endothelial cells and cardiomyocytes is ameliorated by nitrone spin traps and ebselen. Role of reactive oxygen and nitrogen species. Journal of Biological Chemistry 2000 275 43 33585 33592 2-s2.0-0034721770 10.1074/jbc.M003890200
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.43 , pp. 33585-33592
    • Kotamraju, S.1    Konorev, E.A.2    Joseph, J.3    Kalyanaraman, B.4
  • 54
    • 18844383751 scopus 로고    scopus 로고
    • Combined oral delivery of ebselen and allopurinol reduces multiple cisplatin toxicities in rat breast and ovarian cancer models while enhancing anti-tumor activity
    • 2-s2.0-18844383751 10.1097/00001813-200506000-00013
    • Lynch E. D., Gu R., Pierce C., Kil J., Combined oral delivery of ebselen and allopurinol reduces multiple cisplatin toxicities in rat breast and ovarian cancer models while enhancing anti-tumor activity. Anti-Cancer Drugs 2005 16 5 569 579 2-s2.0-18844383751 10.1097/00001813-200506000-00013
    • (2005) Anti-Cancer Drugs , vol.16 , Issue.5 , pp. 569-579
    • Lynch, E.D.1    Gu, R.2    Pierce, C.3    Kil, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.