Diaryl chalcogenides as selective inhibitors of thioredoxin reductase and potential antitumor agents

Anticancer Research

Volumn 17, Issue 6 D, 1997, Pages 4599-4605

  Engman, Lars ^a   Cotgreave, Ian ^b   Angulo, Miguel ^c   Taylor, Charles W ^c   Paine Murrieta, Gillian D ^c   Powis, Garth ^c  

^a UPPSALA UNIVERSITY   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UNIVERSITY OF ARIZONA   (United States)

Author keywords

Antitumor activity; Organoselenium; Organotellurium; Thioredoxin reductase

Indexed keywords

ANTINEOPLASTIC AGENT; DIARYL CHALCOGENIDE; EBSELEN; ENZYME INHIBITOR; FLAVOPROTEIN; GLUTATHIONE REDUCTASE; ORGANOSELENIUM DERIVATIVE; ORGANOTELLURIUM DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SELENOCYSTEINE; THIOREDOXIN; THIOREDOXIN REDUCTASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CELL GROWTH; CELL TRANSFORMATION; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ANTINEOPLASTIC AGENTS; BINDING, COMPETITIVE; BREAST NEOPLASMS; CELL DIVISION; COLONIC NEOPLASMS; ENZYME INHIBITORS; FEMALE; HUMANS; KINETICS; MICE; MICE, NUDE; ORGANOMETALLIC COMPOUNDS; ORGANOSELENIUM COMPOUNDS; SELENIUM; STRUCTURE-ACTIVITY RELATIONSHIP; TELLURIUM; THIOREDOXIN REDUCTASE (NADPH); TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

EID: 0031425497     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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