NIH molecular libraries initiative

Science

Volumn 306, Issue 5699, 2004, Pages 1138-1139

  Austin, Christopher P ^a   Brady, Linda S ^b   Insel, Thomas R ^b   Collins, Francis S ^a  

^a NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; HORMONE RECEPTOR; MESSENGER RNA; NUCLEIC ACID; PHOSPHOTRANSFERASE; SMALL INTERFERING RNA;

BIOLOGY;

ABSORPTION; BIOTECHNOLOGY; CELL ISOLATION; CELL MEMBRANE PERMEABILITY; CHEMICAL GENETICS; CHEMICAL MODIFICATION; COST; DRUG INDUSTRY; DRUG SELECTIVITY; EXCRETION; GENE LOCUS; GENE SEQUENCE; GENE TARGETING; GENETIC VARIABILITY; HUMAN GENOME; INFORMATION SCIENCE; INSTRUMENTATION; MEDICAL RESEARCH; METABOLISM; MOLECULAR LIBRARY; MOLECULAR PROBE; ORGANIZATION AND MANAGEMENT; PRIORITY JOURNAL; PROTEIN ISOLATION; PUBLIC HEALTH; REVIEW; ROBOTICS; TOXICOLOGY;

CHEMISTRY, PHARMACEUTICAL; COMPUTATIONAL BIOLOGY; DATABASES, FACTUAL; DRUG EVALUATION, PRECLINICAL; GENOME, HUMAN; HUMANS; INTELLECTUAL PROPERTY; MOLECULAR PROBES; MOLECULAR STRUCTURE; NATIONAL INSTITUTES OF HEALTH (U.S.); PRIVATE SECTOR; PUBLIC SECTOR; TECHNOLOGY, PHARMACEUTICAL; UNITED STATES;

EID: 8444225024     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1105511     Document Type: Review

References (22)

1. E. Zerhouni, Science 302, 63 (2003).
2. http://nihroadmap.nih.gov/molecularlibraries/index.asp.
3. J. Kaiser, Science 304, 1728 (2004).
4. D. Janssen, Bio-IT World 3, 1 (2004).
5. F. S. Collins, Nature Rev. Drug Discov. 3, 640 (2004).
6. J. Couzin, Science 302, 218 (2003).
7. C. P. Austin, Curr. Opin. Chem. Biol. 7, 511 (2003).
8. International Human Genome Sequencing Consortium, Nature 431, 931 (2004).
9. J. Drews, Science 287, 1960 (2000).
10. A. L. Hopkins, C. R. Groom, Nature Rev. Drug Discov. 1, 727 (2002).
11. http://nihroadmap.nih.gov/molecularlibraries/grants.asp.
12. http://grants1.nih.gov/grants/guide/rfa-files/RFA-RM-04-017.html.
13. www.genome.gov/12512295
14. http://pubs.acs.org/cen/news/8235/8235notw5.html.
15. http://pubchem.ncbi.nlm.nih.gov/.
16. N. P. Savchuk, K. V. Balakin, S. E. Tkachenko, Curr. Opin. Chem. Biol. 8, 412-417 (2004).
17. M. A. Lindsay, Nature Rev. Drug Discov. 2, 831-834 (2003).
18. K. H. Bleicher, H. J. Bohm, K. Muller, A. I. Alanine, Nature Rev. Drug Discov. 2, 369-78 (2003).
19. J. A. DiMasi, R. W. Hansen, H. G. Grabowski, J. Health Econ. 22, 151 (2003).
20. http://nihroadmap.nih.gov/clinicalresearch/overview-translational.asp
21. http://grants1.nih.gov/grants/guide/notice-files/NOT-RM-04-014.html
22. The Molecular Libraries Roadmap is a trans-NIH initiative conceptualized and implemented with the participation of all Institutes and Centers; see http://nihroadmap.nih.gov/molecularlibraries/members.asp for the members of the Molecular Libraries Project Team. The authors are leaders of the initiative.