Targeting CDC25C, PLK1 and CHK1 to overcome Docetaxel resistance induced by loss of LZTS1 in prostate cancer

Oncotarget

Volumn 5, Issue 3, 2014, Pages 667-678

  Al Nakouzi, Nader ^a,e   Cotteret, Sophie ^a,e   Commo, Frédéric ^a,e   Gaudin, Catherine ^a,e   Rajpar, Shanna ^a,e   Dessen, Philippe ^b,e   Vielh, Philippe ^a,c,e   Fizazi, Karim ^a,d,e   Chauchereau, Anne ^a,e  

^a Universite Paris Sud   (France)

^b INSERM   (France)

^c Department of Pathology HistoCytoPathology Unit Translational Research Laboratory and Biobank Gustave Roussy   (France)

^d NONE   (France)

^e UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

Cdc25c; CHEK1; Chemoresistance; LZTS1; PLK1; Prostate cancer

Indexed keywords

ANTINEOPLASTIC AGENT; CELL CYCLE PROTEIN; CHECKPOINT KINASE 1; DOCETAXEL; NSC 663284; POLO LIKE KINASE 1; PROTEIN CDC25C; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; CDC25C PROTEIN, HUMAN; DNA BINDING PROTEIN; LZTS1 PROTEIN, HUMAN; ONCOPROTEIN; POLO-LIKE KINASE 1; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE PHOSPHATASE; TAXOID; TRANSCRIPTOME; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; CANCER CELL CULTURE; CANCER RESISTANCE; CELL CYCLE ARREST; CELL CYCLE REGULATION; CELL DEATH; CONTROLLED STUDY; DNA METHYLATION; DRUG TARGETING; ENZYME INHIBITION; GENE; GENE EXPRESSION PROFILING; GENE LOSS; GENE SILENCING; LZTS1 GENE; MICROARRAY ANALYSIS; PHARMACOGENETICS; PROMOTER REGION; PROSTATE CANCER; ANTAGONISTS AND INHIBITORS; APOPTOSIS; DEFICIENCY; DRUG EFFECTS; DRUG RESISTANCE; GENETIC TRANSFECTION; GENETICS; HUMAN; MALE; METABOLISM; MOLECULARLY TARGETED THERAPY; PATHOLOGY; PROSTATIC NEOPLASMS, CASTRATION-RESISTANT; TISSUE MICROARRAY; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CDC25 PHOSPHATASES; CELL CYCLE PROTEINS; CELL LINE, TUMOR; DNA-BINDING PROTEINS; DRUG RESISTANCE, NEOPLASM; GENE KNOCKDOWN TECHNIQUES; HUMANS; MALE; MOLECULAR TARGETED THERAPY; PROSTATIC NEOPLASMS, CASTRATION-RESISTANT; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; RNA, SMALL INTERFERING; TAXOIDS; TISSUE ARRAY ANALYSIS; TRANSCRIPTOME; TRANSFECTION; TUMOR SUPPRESSOR PROTEINS;

EID: 84896819927     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.1574     Document Type: Article

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