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Volumn 8, Issue 2, 2014, Pages 143-150

Biomarkers of eosinophilic inflammation in asthma

Author keywords

allergy; biomarkers; biopsy; eosinophils; inflammation; nitric oxide; radioligands; SPECT CT; sputum

Indexed keywords

BIOLOGICAL MARKER; EOSINOPHIL CATIONIC PROTEIN; EOSINOPHIL GRANULE PROTEIN; IMMUNOGLOBULIN E; INTERLEUKIN 4; INTERLEUKIN 5; MEPOLIZUMAB; NITRIC OXIDE; RESLIZUMAB; TRANSCRIPTION FACTOR RUNX2;

EID: 84896792476     PISSN: 17476348     EISSN: 17476356     Source Type: Journal    
DOI: 10.1586/17476348.2014.880052     Document Type: Article
Times cited : (23)

References (71)
  • 1
    • 84868627139 scopus 로고    scopus 로고
    • Use of 111-indium-labeled autologous eosinophils to establish the in vivo kinetics of human eosinophils in healthy subjects
    • Farahi N, Singh NR, Heard S, et al. Use of 111-indium-labeled autologous eosinophils to establish the in vivo kinetics of human eosinophils in healthy subjects. Blood 2012; 120(19):4068-711
    • (2012) Blood , vol.120 , Issue.19 , pp. 4068-4711
    • Farahi, N.1    Singh, N.R.2    Heard, S.3
  • 2
    • 84871482550 scopus 로고    scopus 로고
    • Eosinophils: Changing perspectives in health and disease
    • Rosenberg HF, Dyer KD, Foster PS. Eosinophils: changing perspectives in health and disease. Nat Rev Immunol 2013;13(1): 9-222
    • (2013) Nat Rev Immunol , vol.13 , Issue.1 , pp. 9-222
    • Rosenberg, H.F.1    Dyer, K.D.2    Foster, P.S.3
  • 3
    • 0347499617 scopus 로고    scopus 로고
    • The role of eosinophils in host defense against helminth parasites
    • Klion AD, Nutman TB. The role of eosinophils in host defense against helminth parasites. J Allergy Clin Immunol 2004; 113(1):30-77
    • (2004) J Allergy Clin Immunol , vol.113 , Issue.1 , pp. 30-77
    • Klion, A.D.1    Nutman, T.B.2
  • 4
    • 63149136492 scopus 로고    scopus 로고
    • Eosinophil deficiency compromises parasite survival in chronic nematode infection
    • Fabre V, Beiting DP, Bliss SK, et al. Eosinophil deficiency compromises parasite survival in chronic nematode infection. J Immunol 2009:182(3): 1577-833
    • (2009) J Immunol , vol.182 , Issue.3 , pp. 1577-1833
    • Fabre, V.1    Beiting, D.P.2    Bliss, S.K.3
  • 5
    • 84860679595 scopus 로고    scopus 로고
    • Asthma phenotypes: The evolution from clinical to molecular approaches
    • Wenzel SE. Asthma phenotypes: the evolution from clinical to molecular approaches. Nat Med 2012;18(5):716-255
    • (2012) Nat Med , vol.18 , Issue.5 , pp. 716-255
    • Wenzel, S.E.1
  • 7
    • 0031226757 scopus 로고    scopus 로고
    • Eosinophil-associated TGF-beta1 mRNA expression and airways fibrosis in bronchial asthma
    • Minshall EM, Leung DY, Martin RJ, et al. Eosinophil-associated TGF-beta1 mRNA expression and airways fibrosis in bronchial asthma. Am J Respir Cell Mol Biol 1997; 17(3):326-333
    • (1997) Am J Respir Cell Mol Biol , vol.17 , Issue.3 , pp. 326-333
    • Minshall, E.M.1    Leung, D.Y.2    Martin, R.J.3
  • 8
    • 85047693849 scopus 로고    scopus 로고
    • Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics
    • Flood-Page P, Menzies-Gow A, Phipps S, et al. Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics. J Clin Invest 2003;112(7):1029-366
    • (2003) J Clin Invest , vol.112 , Issue.7 , pp. 1029-1366
    • Flood-Page, P.1    Menzies-Gow, A.2    Phipps, S.3
  • 9
    • 0024998101 scopus 로고
    • Reactive oxygen species and airway inflammation
    • Barnes PJ. Reactive oxygen species and airway inflammation. Free Radic Biol Med 1990;9(3):235-433
    • (1990) Free Radic Biol Med , vol.9 , Issue.3 , pp. 235-433
    • Barnes, P.J.1
  • 10
    • 0025037094 scopus 로고
    • Eosinophilic inflammation in asthma
    • Bousquet J, Chanez P, Lacoste JY, et al. Eosinophilic inflammation in asthma. N Engl J Med 1990;323(15):1033-99
    • (1990) N Engl J Med , vol.323 , Issue.15 , pp. 1033-1099
    • Bousquet, J.1    Chanez, P.2    Lacoste, J.Y.3
  • 11
    • 0025721948 scopus 로고
    • Evidence of ongoing mast cell and eosinophil degranulation in symptomatic asthma airway
    • Broide D, Gleich G, Cuomo A, et al. Evidence of ongoing mast cell and eosinophil degranulation in symptomatic asthma airway. J Allergy Clin Immunol 1991;88(4):637-488
    • (1991) J Allergy Clin Immunol , vol.88 , Issue.4 , pp. 637-488
    • Broide, D.1    Gleich, G.2    Cuomo, A.3
  • 13
    • 0032924480 scopus 로고    scopus 로고
    • Effect of inhaled budesonide on lung function and airway inflammation. Assessment by various inflammatory markers in mild asthma
    • Lim S, Jatakanon A, John M, et al. Effect of inhaled budesonide on lung function and airway inflammation. Assessment by various inflammatory markers in mild asthma. Am J Respir Crit Care Med 1999;159(1):22-300
    • (1999) Am J Respir Crit Care Med , vol.159 , Issue.1 , pp. 22-300
    • Lim, S.1    Jatakanon, A.2    John, M.3
  • 14
    • 81455155725 scopus 로고    scopus 로고
    • Reslizumab for poorly controlled, eosinophilic asthma: A randomized, placebo-controlled study
    • Castro M, Mathur S, Hargreave F, et al. Reslizumab for poorly controlled, eosinophilic asthma: a randomized, placebo-controlled study. Am J Respir Crit Care Med 2011;184(10):1125-322
    • (2011) Am J Respir Crit Care Med , vol.184 , Issue.10 , pp. 1125-1322
    • Castro, M.1    Mathur, S.2    Hargreave, F.3
  • 15
    • 84879401471 scopus 로고    scopus 로고
    • Dupilumab in persistent asthma with elevated eosinophil levels
    • Wenzel S, Ford L, Pearlman D, et al. Dupilumab in persistent asthma with elevated eosinophil levels. N Engl J Med 2013;368:2455-666
    • N Engl J Med , vol.2013 , Issue.368 , pp. 2455-2666
    • Wenzel, S.1    Ford, L.2    Pearlman, D.3
  • 16
    • 80053084755 scopus 로고    scopus 로고
    • Lebrikizumab treatment in adults with asthma
    • Corren J, Lemanske RF, Hanania NA, et al. Lebrikizumab treatment in adults with asthma. N Engl J Med 2011;365(12): 1088-988
    • (2011) N Engl J Med , vol.365 , Issue.12 , pp. 1088-1988
    • Corren, J.1    Lemanske, R.F.2    Hanania, N.A.3
  • 17
    • 61849155730 scopus 로고    scopus 로고
    • Mepolizumab for prednisone-dependent asthma with sputum eosinophilia
    • Nair P, Pizzichini MM, Kjarsgaard M, et al. Mepolizumab for prednisone-dependent asthma with sputum eosinophilia. N Engl J Med 2009;360(10):985-933
    • (2009) N Engl J Med , vol.360 , Issue.10 , pp. 985-933
    • Nair, P.1    Pizzichini, M.M.2    Kjarsgaard, M.3
  • 18
    • 0034907372 scopus 로고    scopus 로고
    • Omalizumab, anti-IgE recombinant humanized monoclonal antibody, for the treatment of severe allergic asthma
    • Busse W, Corren J, Lanier BQ, et al. Omalizumab, anti-IgE recombinant humanized monoclonal antibody, for the treatment of severe allergic asthma. J Allergy Clin Immunol 2001;108(2): 184-900
    • (2001) J Allergy Clin Immunol , vol.108 , Issue.2 , pp. 184-900
    • Busse, W.1    Corren, J.2    Lanier, B.Q.3
  • 19
    • 0037438409 scopus 로고    scopus 로고
    • Eosinophil's role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway
    • Flood-Page PT, Menzies-Gow AN, Kay AB, Robinson DS. Eosinophil's role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway. Am J Respir Crit Care Med 2003;167(2): 199-2044
    • (2003) Am J Respir Crit Care Med , vol.167 , Issue.2 , pp. 199-2044
    • Flood-Page, P.T.1    Menzies-Gow, A.N.2    Kay, A.B.3    Robinson, D.S.4
  • 20
    • 61849086181 scopus 로고    scopus 로고
    • Mepolizumab and exacerbations of refractory eosinophilic asthma
    • Haldar P, Brightling CE, Hargadon B, et al. Mepolizumab and exacerbations of refractory eosinophilic asthma. N Engl J Med 2009;360:973-844
    • (2009) N Engl J Med , vol.360 , pp. 973-844
    • Haldar, P.1    Brightling, C.E.2    Hargadon, B.3
  • 21
    • 6644229440 scopus 로고    scopus 로고
    • Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response
    • Leckie MJ, Brinke AT, Khan J, et al. Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response. Lancet 2000;356(9248):2144-88
    • (2000) Lancet , vol.356 , Issue.9248 , pp. 2144-2188
    • Leckie, M.J.1    Brinke, A.T.2    Khan, J.3
  • 22
    • 0034015886 scopus 로고    scopus 로고
    • Relationship between exhaled nitric oxide and mucosal eosinophilic inflammation in mild to moderately severe asthma
    • Lim S, Jatakanon A, Meah S, et al. Relationship between exhaled nitric oxide and mucosal eosinophilic inflammation in mild to moderately severe asthma. Thorax 2000;55(3):184-88
    • (2000) Thorax , vol.55 , Issue.3 , pp. 184-188
    • Lim, S.1    Jatakanon, A.2    Meah, S.3
  • 23
    • 0031917809 scopus 로고    scopus 로고
    • Dissociation between airway inflammation and airway hyperresponsiveness in allergic asthma
    • Crimi E, Spanevello A, Neri M, et al. Dissociation between airway inflammation and airway hyperresponsiveness in allergic asthma. Am J Respir Crit Care Med 1998; 157(1):4-99
    • (1998) Am J Respir Crit Care Med , vol.157 , Issue.1 , pp. 4-99
    • Crimi, E.1    Spanevello, A.2    Neri, M.3
  • 24
    • 24644515785 scopus 로고    scopus 로고
    • Exhaled breath condensate: Methodological recommendations and unresolved questions
    • Horváth I, Hunt J, Barnes PJ, et al. Exhaled breath condensate: methodological recommendations and unresolved questions. Eur Respir J 2005;26(3):523-488
    • (2005) Eur Respir J , vol.26 , Issue.3 , pp. 523-488
    • Horváth, I.1    Hunt, J.2    Barnes, P.J.3
  • 25
    • 29844433423 scopus 로고    scopus 로고
    • Methodological improvements for measuring eicosanoids and cytokines in exhaled breath condensate
    • Tufvesson E, Bjermer L. Methodological improvements for measuring eicosanoids and cytokines in exhaled breath condensate. Respir Med 2006;100(1):34-88
    • (2006) Respir Med , vol.100 , Issue.1 , pp. 34-88
    • Tufvesson, E.1    Bjermer, L.2
  • 27
    • 33947310744 scopus 로고    scopus 로고
    • Hydrogen peroxide in exhaled breath condensate (EBC) vs eosinophil count in induced sputum (IS) in parenchymal vs airways lung diseases
    • Fireman E, Shtark M, Priel IE, et al. Hydrogen peroxide in exhaled breath condensate (EBC) vs eosinophil count in induced sputum (IS) in parenchymal vs airways lung diseases. Inflammation 2007; 30(1-2):44-511
    • (2007) Inflammation , vol.30 , Issue.1-2 , pp. 44-511
    • Fireman, E.1    Shtark, M.2    Priel, I.E.3
  • 28
    • 80052438246 scopus 로고    scopus 로고
    • American Thoracic Society Committee on Interpretation of Exhaled Nitric Oxide Levels (FENO) for Clinical Applications. An official ATS clinical practice guideline: Interpretation of exhaled nitric oxide levels (FENO) for clinical applications
    • Dweik RA, Boggs PB, Erzurum SC, et al. American Thoracic Society Committee on Interpretation of Exhaled Nitric Oxide Levels (FENO) for Clinical Applications. An official ATS clinical practice guideline: interpretation of exhaled nitric oxide levels (FENO) for clinical applications. Am J Respir Crit Care Med 2011;184:602-155
    • (2011) Am J Respir Crit Care Med , vol.184 , pp. 602-155
    • Dweik, R.A.1    Boggs, P.B.2    Erzurum, S.C.3
  • 29
    • 84870446529 scopus 로고    scopus 로고
    • The utility of fractional exhaled nitric oxide suppression in the identification of nonadherence in difficult asthma
    • McNicholl DM, Stevenson M, McGarvey LP, Heaney LG. The utility of fractional exhaled nitric oxide suppression in the identification of nonadherence in difficult asthma. Am J Respir Crit Care Med 2012;186(11):1102-88
    • (2012) Am J Respir Crit Care Med , vol.186 , Issue.11 , pp. 1102-1188
    • McNicholl, D.M.1    Stevenson, M.2    McGarvey, L.P.3    Heaney, L.G.4
  • 30
    • 19444385389 scopus 로고    scopus 로고
    • Use of exhaled nitric oxide measurements to guide treatment in chronic asthma
    • Smith AD, Cowan JO, Brassett KP, et al. Use of exhaled nitric oxide measurements to guide treatment in chronic asthma. N Engl J Med 2005;352(21):2163-733
    • (2005) N Engl J Med , vol.352 , Issue.21 , pp. 2163-2733
    • Smith, A.D.1    Cowan, J.O.2    Brassett, K.P.3
  • 31
    • 34547557916 scopus 로고    scopus 로고
    • The use of exhaled nitric oxide to guide asthma management: A randomized controlled trial
    • Shaw DE, Berry MA, Thomas M, et al. The use of exhaled nitric oxide to guide asthma management: a randomized controlled trial. Am J Respir Crit Care Med 2007;176(3):231-77
    • (2007) Am J Respir Crit Care Med , vol.176 , Issue.3 , pp. 231-277
    • Shaw, D.E.1    Berry, M.A.2    Thomas, M.3
  • 32
    • 52049108262 scopus 로고    scopus 로고
    • Management of asthma based on exhaled nitric oxide in addition to guideline-based treatment for inner-city adolescents and young adults: A randomised controlled trial
    • Szefler SJ, Mitchell H, Sorkness CA, et al. Management of asthma based on exhaled nitric oxide in addition to guideline-based treatment for inner-city adolescents and young adults: a randomised controlled trial. Lancet 2008;372(9643):1065-722
    • (2008) Lancet , vol.372 , Issue.9643 , pp. 1065-1722
    • Szefler, S.J.1    Mitchell, H.2    Sorkness, C.A.3
  • 33
    • 84857429187 scopus 로고    scopus 로고
    • A systematic review and meta-analysis: Tailoring asthma treatment on eosinophilic markers (exhaled nitric oxide or sputum eosinophils)
    • Petsky HL, Cates CJ, Lasserson TJ, et al. A systematic review and meta-analysis: tailoring asthma treatment on eosinophilic markers (exhaled nitric oxide or sputum eosinophils). Thorax 2012;67(3):199-2088
    • (2012) Thorax , vol.67 , Issue.3 , pp. 199-2088
    • Petsky, H.L.1    Cates, C.J.2    Lasserson, T.J.3
  • 34
    • 84882896337 scopus 로고    scopus 로고
    • Biomarker surrogates do not accurately predict sputum eosinophil and neutrophil percentages in asthmatic subjects
    • e122
    • Hastie AT, Moore WC, Li H, et al. Biomarker surrogates do not accurately predict sputum eosinophil and neutrophil percentages in asthmatic subjects. J Allergy Clin Immunol 2013;132(1):72-80.e122
    • (2013) J Allergy Clin Immunol , vol.132 , Issue.1 , pp. 72-80
    • Hastie, A.T.1    Moore, W.C.2    Li, H.3
  • 35
    • 0020060624 scopus 로고
    • An epidemiological study of the interrelationships of total serum immunoglobulin E, allergy skin-test reactivity, and eosinophilia
    • Halonen M, Barbee R, Lebowitz M, Burrows B. An epidemiological study of the interrelationships of total serum immunoglobulin E, allergy skin-test reactivity, and eosinophilia. J Allergy Clin Immunol 1982;69(2):221-88
    • (1982) J Allergy Clin Immunol , vol.69 , Issue.2 , pp. 221-288
    • Halonen, M.1    Barbee, R.2    Lebowitz, M.3    Burrows, B.4
  • 36
    • 0029811472 scopus 로고    scopus 로고
    • Total serum IgE is associated with asthma independently of specific IgE levels
    • Sunyer J, Antó JM, Castellsagué J, et al. Total serum IgE is associated with asthma independently of specific IgE levels. Eur Respir J 1996;9(9):1880-44
    • (1996) Eur Respir J , vol.9 , Issue.9 , pp. 1880-1854
    • Sunyer, J.1    Antó, J.M.2    Castellsagué, J.3
  • 37
    • 25844488069 scopus 로고    scopus 로고
    • IgE antibody quantification and the probability of wheeze in preschool children
    • Simpson A, Soderstrom L, Ahlstedt S, et al. IgE antibody quantification and the probability of wheeze in preschool children. J Allergy Clin Immunol 2005;116(4):744-99
    • (2005) J Allergy Clin Immunol , vol.116 , Issue.4 , pp. 744-799
    • Simpson, A.1    Soderstrom, L.2    Ahlstedt, S.3
  • 38
    • 0035001786 scopus 로고    scopus 로고
    • Allergy markers in respiratory epidemiology
    • Baldacci S, Omenaas E, Oryszczyn MP. Allergy markers in respiratory epidemiology. Eur Respir J 2001;17(4):773-900
    • (2001) Eur Respir J , vol.17 , Issue.4 , pp. 773-900
    • Baldacci, S.1    Omenaas, E.2    Oryszczyn, M.P.3
  • 39
    • 7144263723 scopus 로고    scopus 로고
    • Current allergic asthma and rhinitis: Diagnostic efficiency of three commonly used atopic markers (IgE, skin prick tests, and Phadiatop) Results from 8329 randomized adults from the SAPALDIA study. Swiss study on air pollution and lung diseases in adults
    • Tschopp JM, Sistek D, Schindler C, et al. Current allergic asthma and rhinitis: diagnostic efficiency of three commonly used atopic markers (IgE, skin prick tests, and Phadiatop). Results from 8329 randomized adults from the SAPALDIA study. Swiss study on air pollution and lung diseases in adults. Allergy 1998;53(6): 608-133
    • (1998) Allergy , vol.53 , Issue.6 , pp. 608-133
    • Tschopp, J.M.1    Sistek, D.2    Schindler, C.3
  • 40
    • 35649028488 scopus 로고    scopus 로고
    • Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids
    • Woodruff PG, Boushey HA, Dolganov GM, et al. Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids. Proc Natl Acad Sci USA 2007;104(40):15858-633
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.40 , pp. 15858-15643
    • Woodruff, P.G.1    Boushey, H.A.2    Dolganov, G.M.3
  • 41
    • 84865696394 scopus 로고    scopus 로고
    • Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients
    • e100
    • Jia G, Erickson RW, Choy DF, et al. Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients. J Allergy Clin Immunol 2012;130(3):647-54.e100
    • (2012) J Allergy Clin Immunol , vol.130 , Issue.3 , pp. 647-654
    • Jia, G.1    Erickson, R.W.2    Choy, D.F.3
  • 42
    • 33646245681 scopus 로고    scopus 로고
    • Eosinophilia: Secondary, clonal and idiopathic
    • Tefferi A, Patnaik MM, Pardanani A. Eosinophilia: secondary, clonal and idiopathic. Br J Haematol 2006;133(5): 468-922
    • (2006) Br J Haematol , vol.133 , Issue.5 , pp. 468-922
    • Tefferi, A.1    Patnaik, M.M.2    Pardanani, A.3
  • 43
    • 0016864288 scopus 로고
    • Total eosinophil counts in the management of bronchial asthma
    • Horn BR, Robin ED, Theodore J, Van Kessel A. Total eosinophil counts in the management of bronchial asthma. N Engl J Medi 1975;92(22):1152-55
    • (1975) N Engl J Medi , vol.92 , Issue.22 , pp. 1152-1155
    • Horn, B.R.1    Robin, E.D.2    Theodore, J.3    Van Kessel, A.4
  • 44
    • 0141927331 scopus 로고    scopus 로고
    • Glucocorticoid-induced apoptosis in human eosinophils: Mechanisms of action
    • Druilhe A, Létuvé S, Pretolani M. Glucocorticoid-induced apoptosis in human eosinophils: mechanisms of action. Apoptosis 2003;8(5):481-955
    • (2003) Apoptosis , vol.8 , Issue.5 , pp. 481-955
    • Druilhe, A.1    Létuvé, S.2    Pretolani, M.3
  • 45
    • 73749083569 scopus 로고    scopus 로고
    • Effect of omalizumab on peripheral blood eosinophilia in allergic asthma
    • Massanari M, Holgate ST, Busse WW, et al. Effect of omalizumab on peripheral blood eosinophilia in allergic asthma. Respir Med 2010;104(2):188-966
    • (2010) Respir Med , vol.104 , Issue.2 , pp. 188-966
    • Massanari, M.1    Holgate, S.T.2    Busse, W.W.3
  • 46
    • 0019457992 scopus 로고
    • Within-day physiologic variation of leukocyte types in healthy subjects as assayed by two automated leukocyte differential analyzers
    • Winkel P, Statland BE, Saunders AM, et al. Within-day physiologic variation of leukocyte types in healthy subjects as assayed by two automated leukocyte differential analyzers. Am J Clin Pathol 1981;75(5):693-7000
    • (1981) Am J Clin Pathol , vol.75 , Issue.5 , pp. 693-7000
    • Winkel, P.1    Statland, B.E.2    Saunders, A.M.3
  • 47
    • 33847339868 scopus 로고    scopus 로고
    • Eosinophil cationic protein: Is it useful in asthma? A systematic review
    • Koh GC-H, Shek LP-C, Goh DY-T, et al. Eosinophil cationic protein: is it useful in asthma? A systematic review. Respir Med 2007;101(4):696-7055
    • (2007) Respir Med , vol.101 , Issue.4 , pp. 696-7055
    • Gc-H, K.1    Lp-C, S.2    Dy-T, G.3
  • 48
    • 84896777694 scopus 로고    scopus 로고
    • Genomics and proteomics of the human eosinophil
    • James JL, Helen FR, editors Elsevier; CA, USA
    • Venge P. Genomics and proteomics of the human eosinophil. In: James JL, Helen FR, editors. Eosinophils in health and disease. Elsevier; CA, USA: 2013. p. 432-422
    • (2013) Eosinophils in Health and Disease , pp. 432-422
    • Venge, P.1
  • 49
    • 14744284491 scopus 로고    scopus 로고
    • Tests of Eosinophilic Airway Inflammation A national clinical guideline. UK
    • Tests of Eosinophilic Airway Inflammation. In: BTS/SIGN Guideline on the Management of Asthma. A national clinical guideline. UK. 2012; p. 26.
    • (2012) BTS/SIGN Guideline on the Management of Asthma , pp. 26
  • 50
    • 0037202790 scopus 로고    scopus 로고
    • Asthma exacerbations and sputum eosinophil counts: A randomised controlled trial
    • Green RH, Brightling CE, McKenna S, et al. Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial. Lancet 2002;360(9347):1715-211
    • (2002) Lancet , vol.360 , Issue.9347 , pp. 1715-1221
    • Green, R.H.1    Brightling, C.E.2    McKenna, S.3
  • 51
    • 84857431715 scopus 로고    scopus 로고
    • Use of sputum eosinophil counts to guide management in children with severe asthma
    • Fleming L, Wilson N, Regamey N, Bush A. Use of sputum eosinophil counts to guide management in children with severe asthma. Thorax 2012;67(3):193-88
    • (2012) Thorax , vol.67 , Issue.3 , pp. 193-198
    • Fleming, L.1    Wilson, N.2    Regamey, N.3    Bush, A.4
  • 52
    • 0035177659 scopus 로고    scopus 로고
    • Relationship between airway inflammation, hyperresponsiveness, and obstruction in asthma
    • Woodruff PG, Khashayar R, Lazarus SC, et al. Relationship between airway inflammation, hyperresponsiveness, and obstruction in asthma. J Allergy Clin Immunol 2001;108(5):753-88
    • (2001) J Allergy Clin Immunol , vol.108 , Issue.5 , pp. 753-788
    • Woodruff, P.G.1    Khashayar, R.2    Lazarus, S.C.3
  • 53
    • 33845490811 scopus 로고    scopus 로고
    • Airway eosinophilia in children with severe asthma: Predictive values of noninvasive tests
    • Lex C, Ferreira F, Zacharasiewicz A, et al. Airway eosinophilia in children with severe asthma: predictive values of noninvasive tests. Am J Respir Crit Care Med 2006; 174(12):1286-911
    • (2006) Am J Respir Crit Care Med , vol.174 , Issue.12 , pp. 1286-1911
    • Lex, C.1    Ferreira, F.2    Zacharasiewicz, A.3
  • 54
    • 0027939414 scopus 로고
    • Analysis of induced sputum to examine the effects of prednisone on airway inflammation in asthmatic subjects
    • Claman D, Boushey H, Liu J, et al. Analysis of induced sputum to examine the effects of prednisone on airway inflammation in asthmatic subjects. J Allergy Clin Immunol 1994;94(5): 861-99
    • (1994) J Allergy Clin Immunol , vol.94 , Issue.5 , pp. 861-899
    • Claman, D.1    Boushey, H.2    Liu, J.3
  • 55
    • 84860621394 scopus 로고    scopus 로고
    • An official American Thoracic Society clinical practice guideline: The clinical utility of bronchoalveolar lavage cellular analysis in interstitial lung disease
    • Meyer KC, Raghu G, Baughman RP, et al. An official American Thoracic Society clinical practice guideline: the clinical utility of bronchoalveolar lavage cellular analysis in interstitial lung disease. Am J Respir Crit Care Med 2012;185(9):1004-144
    • (2012) Am J Respir Crit Care Med , vol.185 , Issue.9 , pp. 1004-1144
    • Meyer, K.C.1    Raghu, G.2    Baughman, R.P.3
  • 56
    • 0023831561 scopus 로고    scopus 로고
    • Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma. Relationship to bronchial hyperreactivity
    • Wardlaw AJ, Dunnette S, Gleich GJ, et al. Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma. Relationship to bronchial hyperreactivity. Am Rev Respir Dis 1998; 137(1):62-99
    • (1998) Am Rev Respir Dis , vol.137 , Issue.1 , pp. 62-99
    • Wardlaw, A.J.1    Dunnette, S.2    Gleich, G.J.3
  • 57
    • 0026333085 scopus 로고
    • Activated T cells and eosinophilia in bronchoalveolar lavages from subjects with asthma correlated with disease severity
    • Walker C, Kaegi M, Braun P, Blaser K. Activated T cells and eosinophilia in bronchoalveolar lavages from subjects with asthma correlated with disease severity. J Allergy Clin Immunol 1991;88(6):935-422
    • (1991) J Allergy Clin Immunol , vol.88 , Issue.6 , pp. 935-422
    • Walker, C.1    Kaegi, M.2    Braun, P.3    Blaser, K.4
  • 58
    • 0026770585 scopus 로고
    • Bronchiolitis obliterans organizing pneumonia (BOOP): The cytological and immunocytological profile of bronchoalveolar lavage
    • Costabel U, Teschler H, Guzman J. Bronchiolitis obliterans organizing pneumonia (BOOP): the cytological and immunocytological profile of bronchoalveolar lavage. Eur Respir J 1992; 5(7):791-77
    • (1992) Eur Respir J , vol.5 , Issue.7 , pp. 791-787
    • Costabel, U.1    Teschler, H.2    Guzman, J.3
  • 59
    • 0025113661 scopus 로고
    • Diagnostic significance of increased bronchoalveolar lavage fluid eosinophils
    • Allen JN, Davis WB, Pacht ER. Diagnostic significance of increased bronchoalveolar lavage fluid eosinophils. Am Rev Respir Dis 1990;142(3):642-77
    • (1990) Am Rev Respir Dis , vol.142 , Issue.3 , pp. 642-677
    • Allen, J.N.1    Davis, W.B.2    Pacht, E.R.3
  • 60
    • 77956686601 scopus 로고    scopus 로고
    • Resolution of cell-mediated airways diseases
    • Persson CG, Uller L. Resolution of cell-mediated airways diseases. Respir Res 2010;11(1):755
    • (2010) Respir Res , vol.11 , Issue.1 , pp. 755
    • Persson, C.G.1    Uller, L.2
  • 61
    • 84881526953 scopus 로고    scopus 로고
    • British Thoracic Society Guideline for diagnostic flexible bronchoscopy in adults
    • Rand IA Du, Blaikly J, Booton R, et al. British Thoracic Society Guideline for diagnostic flexible bronchoscopy in adults. Thorax 2013;68:i1-i444
    • (2013) Thorax , vol.68
    • Rand Ia, D.U.1    Blaikly, J.2    Booton, R.3
  • 62
    • 77953867912 scopus 로고    scopus 로고
    • Eosinophil-derived neurotoxin in childhood asthma: Correlation with disease severity
    • Kim C-K, Callaway Z, Fletcher R, Koh YY. Eosinophil-derived neurotoxin in childhood asthma: correlation with disease severity. J Asthma 2010;47(5):568-733
    • (2010) J Asthma , vol.47 , Issue.5 , pp. 568-733
    • Kim, C.-K.1    Callaway, Z.2    Fletcher, R.3    Koh, Y.Y.4
  • 63
    • 0026724926 scopus 로고
    • Eosinophil-derived neurotoxin and human liver ribonuclease. Identity of structure and linkage of neurotoxicity to nuclease activity
    • Sorrentino S, Glitz DG, Hamann KJ, et al. Eosinophil-derived neurotoxin and human liver ribonuclease. Identity of structure and linkage of neurotoxicity to nuclease activity. J Biol Chem 1992;267(21):14859-655
    • (1992) J Biol Chem , vol.267 , Issue.21 , pp. 14859-14665
    • Sorrentino, S.1    Glitz, D.G.2    Hamann, K.J.3
  • 64
    • 77953963471 scopus 로고    scopus 로고
    • Eosinophil protein in airway macrophages: A novel biomarker of eosinophilic inflammation in patients with asthma
    • Kulkarni NS, Hollins F, Sutcliffe A, et al. Eosinophil protein in airway macrophages: a novel biomarker of eosinophilic inflammation in patients with asthma. J Allergy Clin Immunol 2010;126(1): 61-9.e33
    • (2010) J Allergy Clin Immunol , vol.126 , Issue.1
    • Kulkarni, N.S.1    Hollins, F.2    Sutcliffe, A.3
  • 65
    • 80052263612 scopus 로고    scopus 로고
    • Lung imaging in asthmatic patients: The picture is clearer
    • Castro M, Fain SB, Hoffman EA, et al. Lung imaging in asthmatic patients: the picture is clearer. J Allergy Clin Immunol 2011;128(3):467-788
    • (2011) J Allergy Clin Immunol , vol.128 , Issue.3 , pp. 467-788
    • Castro, M.1    Fain, S.B.2    Hoffman, E.A.3
  • 66
    • 80455168443 scopus 로고    scopus 로고
    • 18F-FDG uptake rate is a biomarker of eosinophilic inflammation and airway response in asthma
    • Harris RS, Venegas JG, Wongviriyawong C, et al. 18F-FDG uptake rate is a biomarker of eosinophilic inflammation and airway response in asthma. J Nucl Med 2011; 52(11):1713-200
    • (2011) J Nucl Med , vol.52 , Issue.11 , pp. 1713-1210
    • Harris, R.S.1    Venegas, J.G.2    Wongviriyawong, C.3
  • 67
    • 0025719859 scopus 로고
    • An improved immunomagnetic procedure for the isolation of highly purified human blood eosinophils
    • Hansel TT, De Vries IJ, Iff T, et al. An improved immunomagnetic procedure for the isolation of highly purified human blood eosinophils. J Immunol Methods 1991;145(1-2):105-100
    • (1991) J Immunol Methods , vol.145 , Issue.1-2 , pp. 105-100
    • Hansel, T.T.1    De Vries, I.J.2    Iff, T.3
  • 68
    • 0026543833 scopus 로고
    • Imaging inflammation: Current role of labeled autologous leukocytes
    • Petersa M. Imaging inflammation: current role of labeled autologous leukocytes. J Nucl Med 1992;33(1):65-77
    • (1992) J Nucl Med , vol.33 , Issue.1 , pp. 65-77
    • Petersa, M.1
  • 69
    • 79953703981 scopus 로고    scopus 로고
    • Quantification of neutrophil migration into the lungs of patients with chronic obstructive pulmonary disease
    • Ruparelia P, Szczepura KR, Summers C, et al. Quantification of neutrophil migration into the lungs of patients with chronic obstructive pulmonary disease. Eur J Nucl Med Mol Imaging 2011;38(5):911-199
    • (2011) Eur J Nucl Med Mol Imaging , vol.38 , Issue.5 , pp. 911-199
    • Ruparelia, P.1    Szczepura, K.R.2    Summers, C.3
  • 70
    • 84886257912 scopus 로고    scopus 로고
    • Use of 99m Technetium-labeled eosinophils to detect active eosinophilic inflammation in man
    • Farahi N, Loutsios C, Peters AM, et al. Use of 99m Technetium-labeled eosinophils to detect active eosinophilic inflammation in man. Am J Respir Crit Care Med 2013; 188(7):880-22
    • (2013) Am J Respir Crit Care Med , vol.188 , Issue.7 , pp. 880-832
    • Farahi, N.1    Loutsios, C.2    Peters, A.M.3
  • 71
    • 84896774674 scopus 로고    scopus 로고
    • Use of radiolabelled leukocytes for drug evaluation in man
    • Moyer BR, Cheruvu NPS, Hu T, editors Springer; NY, USA
    • Chrystalla L, Neda F, Charlotte S, et al. Use of radiolabelled leukocytes for drug evaluation in man. In: Moyer BR, Cheruvu NPS, Hu T, editors. Pharmaco-imaging in drug and biologics development. Springer; NY, USA: 2014. p. 215-477
    • (2014) Pharmaco-imaging in Drug and Biologics Development , pp. 215-477
    • Chrystalla, L.1    Neda, F.2    Charlotte, S.3


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