Total serum IgE is associated with asthma independently of specific IgE levels

European Respiratory Journal

Volumn 9, Issue 9, 1996, Pages 1880-1884

  Sunyer, J ^a,b   Anto J M ^a   Castellsague J ^a   Soriano, J B ^a   Roca, J ^a  

^a HOSPITAL CLÍNIC   (Spain)

^b INST MUNIC D INVESTIGACIO MEDICA   (Spain)

Author keywords

Allergens; Asthma; Atopy; Bronchial responsiveness; Specific serum immunoglobulin E; Total serum immunoglobulin E

Indexed keywords

IMMUNOGLOBULIN E;

ADULT; ARTICLE; ASTHMA; BRONCHUS REACTIVITY; CONTROLLED STUDY; FEMALE; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

EID: 0029811472     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: 10.1183/09031936.96.09091880     Document Type: Article

References (26)

1. Burrows B, Martinez FD, Halonen M, Barbee RA, Cline MG. Association of asthma with serum IgE levels and skin-test reactivity to allergens. N Engl J Med 1989; 320:271-277.
2. Freidhoff LR, Marsh DG. Relationship among asthma, serum IgE levels, and skin test reactivity to inhaled allergens. Int Arch Allergy Appl Immunol 1993; 100:355-361.
3. Grainger DN, Stenton SC, Aver AJ, Duddridge M, Walters EH, Hendrick DJ. The relationship between atopy and nonspecific bronchial responsiveness. Clin Exp Allergy 1990; 20:181-187.
4. O'Connor GT, Sparrow D, Segal MR, Weiss ST. Smoking, atopy, and methacholine airway responsiveness among middle-aged elderly men: the Normative Aging Study. Am Rev Respir Dis 1989; 140: 1520-1526.
5. Tollerud DJ, O'Connor GT, Sparrow D, Weiss ST. Asthma, hay fever, and phlegm production associated with distinct patterns of allergy skin test reactivity, eosinophilia, and serum IgE levels: the Normative Aging Study. Am Rev Respir Dis 1991; 144:776-781.
6. Sears MR, Burrows B, Flannery EM, Herbison GP, Hewitt CJ, Holdaway MD. Relation between airway responsiveness and serum IgE in children with asthma and in apparently normal children. N Engl J Med 1991; 325: 1067-1071.
7. Pattemore PK, Asher MI, Harrison AC, Mitchell EA, Rea HH, Stewart AW. The interrelationship among bronchial hyperresponsiveness, the diagnosis of asthma, and asthma symptoms. Am Rev Respir Dis 1990; 142:549-554.
8. Mortagy AK, Howell JBL, Waters WE. Respiratory symptoms and bronchial reactivity: identification of a syndrome and its relation to asthma. Br Med J 1986; 293:525-529.
9. Toelle BG, Peat JK, Salome CM, Mellis CM, Woolcock AJ. Toward a definition of asthma for epidemiology. Am Rev Respir Dis 1992; 146:633-637.
10. Peat JK, Toelle BG, Salome CM, Woolcock AJ. Predictive nature of bronchial responsiveness and respiratory symptoms in a one year cohort study of Sydney school children. Eur Respir J 1993; 6:662-669.
11. Bumey PGJ, Luczynska C, Chinn S, Jarvis D, for the European Community Respiratory Health Survey. The European Community Respiratory Health Survey. Eur Respir J 1994; 7:954-960.
12. Enarson DA, Vedal S, Schulzer M, Dybuncio A, Chan-Yeung M. Asthma, asthma-like symptoms, chronic bronchitis and the degree of bronchial hyperresponsiveness in epidemiologic surveys. Am Rev Respir Dis 1987; 136:613-617.
13. Samet JM. Epidemiological approaches for the identification of asthma. Chest 1987; 91 (Suppl. 6): 74S-78S.
14. American Thoracic Society. Standardization of spirometry: 1987 update. Am Rev Respir Dis 1987; 136: 1285-1298.
15. Cox DR, Snell EJ. Analysis of binary data. 2nd edn. London, Chapman & Hall, 1989.
16. Mosmann TR, Coffman RL. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional patterns. Annu Rev Immunol 1989; 7:145-173.
17. Johansson SGO. Raised levels of a new immunoglobulin class IgND in asthma. Lancet 1967; ii:951-953.
18. Burrows B, Martinez FD, Cline MG, Lebowitz MD. The relationship between paternal and children's serum IgE and asthma. Am J Respir Crit Care Med 1995; 152: 1497-1500.
19. Platts-Mills TAB, Pollart SM. Asthma and serum levels of IgE (letter). N Engl J Med 1989; 320: 1696.
20. Valenta R, Duchene M, Pettenburger K, et al. Identification of profilin as a novel pollen allergen; IgE autoreactivity in sensitized individuals. Science 1991; 253:557-559.
21. Marsh DG, Neely JD, Breazeale DR, et al. Linkage analysis of IL-4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations. Science 1994; 264: 1152-1156.
22. Gauchat JF, Henchoz S, Mazzei G, et al. Induction of human IgE synthesis in B-cells by mast cells and basophils. Nature 1993; 365:340-343.
23. Bradding P, Feather IH, Howarth PH, et al. Interleukin-4 is localized to and released by human mast cells. J Exp Med 1992; 176: 1381-1386.
24. Postma DS, Bleecker ER, Amelug PJ, e al. Genetic susceptibility to asthma: bronchial hyperresponsiveness coinherited with a major gene for atopy. N Engl J Med 1995; 333:894-900.
25. Herwerden L, Harrap SB, Wong ZY, et al. Linkage of high-affinity IgE receptor gene with bronchial hyperreactivity, even in absence of atopy. Lancet 1995; 346: 1262-1265.
26. Chinn S, Zannolin E, Lai E, Jarvis D, Luczynska CM, Burney PGJ. Adjustment of reported prevalence of respiratory symptoms for nonresponse in a multicentre health study. Int J Epidemiol 1995; 24:603-611.