메뉴 건너뛰기




Volumn 9, Issue 2, 2014, Pages

Dietary quercetin supplementation in mice increases skeletal muscle PGC1α expression, improves mitochondrial function and attenuates insulin resistance in a time-specific manner

Author keywords

[No Author keywords available]

Indexed keywords

ACYLCARNITINE; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; QUERCETIN; INSULIN; PPARGC1A PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

EID: 84896774151     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0089365     Document Type: Article
Times cited : (62)

References (40)
  • 3
    • 41949114990 scopus 로고    scopus 로고
    • Role of mitochondrial dysfunction in insulin resistance
    • DOI 10.1161/CIRCRESAHA.107.165472, PII 0000301220080229000005
    • Kim JA, Wei Y, Sowers JR (2008) Role of mitochondrial dysfunction in insulin resistance. Circ Res 102: 401-414. (Pubitemid 351651099)
    • (2008) Circulation Research , vol.102 , Issue.4 , pp. 401-414
    • Kim, J.-A.1    Wei, Y.2    Sowers, J.R.3
  • 4
    • 37449020075 scopus 로고    scopus 로고
    • Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance
    • Koves TR, Ussher JR, Noland RC, Slentz D, Mosedale M, et al. (2008) Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance. Cell Metabolism 7: 45-56.
    • (2008) Cell Metabolism , vol.7 , pp. 45-56
    • Koves, T.R.1    Ussher, J.R.2    Noland, R.C.3    Slentz, D.4    Mosedale, M.5
  • 5
    • 0026040907 scopus 로고
    • Development of muscle insulin resistance after liver insulin resistance in high-fatfed rats
    • Kraegen EW, Clark PW, Jenkins AB, Daley EA, Chisholm DJ, et al. (1991) Development of muscle insulin resistance after liver insulin resistance in high-fatfed rats. Diabetes 40: 1397-1403.
    • (1991) Diabetes , vol.40 , pp. 1397-1403
    • Kraegen, E.W.1    Clark, P.W.2    Jenkins, A.B.3    Daley, E.A.4    Chisholm, D.J.5
  • 6
    • 34447511610 scopus 로고    scopus 로고
    • Peroxisome Proliferator Activator Receptor γ Coactivator-1 Expression Is Reduced in Obesity
    • Crunkhorn S, Dearie F, Mantzoros C, Gami H, da Silva WS, et al. (2007) Peroxisome Proliferator Activator Receptor γ Coactivator-1 Expression Is Reduced in Obesity. Journal of Biological Chemistry 282: 15439-15450.
    • (2007) Journal of Biological Chemistry , vol.282 , pp. 15439-15450
    • Crunkhorn, S.1    Dearie, F.2    Mantzoros, C.3    Gami, H.4    Da Silva, W.S.5
  • 8
    • 25844432311 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency
    • DOI 10.1074/jbc.M507621200
    • Koves TR, Li P, An J, Akimoto T, Slentz D, et al. (2005) Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency. J Biol Chem 280: 33588-33598. (Pubitemid 41397160)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.39 , pp. 33588-33598
    • Koves, T.R.1    Li, P.2    An, J.3    Akimoto, T.4    Slentz, D.5    Ilkayeva, O.6    Dohm, G.L.7    Yan, Z.8    Newgard, C.B.9    Muoio, D.M.10
  • 9
  • 12
    • 0037102256 scopus 로고    scopus 로고
    • Transcriptional co-activator PGC-1[alpha] drives the formation of slow-twitch muscle fibres
    • Lin J, Wu H, Tarr PT, Zhang C-Y, Wu Z, et al. (2002) Transcriptional co-activator PGC-1[alpha] drives the formation of slow-twitch muscle fibres. Nature 418: 797-801.
    • (2002) Nature , vol.418 , pp. 797-801
    • Lin, J.1    Wu, H.2    Tarr, P.T.3    Zhang, C.-Y.4    Wu, Z.5
  • 13
    • 21344444333 scopus 로고    scopus 로고
    • A high-fat diet coordinately downregulates genes required for mitochondrial oxidative phosphorylation in skeletal muscle
    • DOI 10.2337/diabetes.54.7.1926
    • Sparks LM, Xie H, Koza RA, Mynatt R, Hulver MW, et al. (2005) A high-fat diet coordinately downregulates genes required for mitochondrial oxidative phosphorylation in skeletal muscle. Diabetes 54: 1926-1933. (Pubitemid 40911253)
    • (2005) Diabetes , vol.54 , Issue.7 , pp. 1926-1933
    • Sparks, L.M.1    Xie, H.2    Koza, R.A.3    Mynatt, R.4    Hulver, M.W.5    Bray, G.A.6    Smith, S.R.7
  • 14
    • 84864278991 scopus 로고    scopus 로고
    • Quercetin decreases inflammatory response and increases insulin action in skeletal muscle of ob/ob mice and in L6 myotubes
    • Anhe GF, Okamoto MM, Kinote A, Sollon C, Lellis-Santos C, et al. (2012) Quercetin decreases inflammatory response and increases insulin action in skeletal muscle of ob/ob mice and in L6 myotubes. Eur J Pharmacol 689: 285-293.
    • (2012) Eur J Pharmacol , vol.689 , pp. 285-293
    • Anhe, G.F.1    Okamoto, M.M.2    Kinote, A.3    Sollon, C.4    Lellis-Santos, C.5
  • 16
    • 84864236699 scopus 로고    scopus 로고
    • Quercetin ameliorates hyperglycemia and dyslipidemia and improves antioxidant status in type 2 diabetic db/db mice
    • Jeong SM, Kang MJ, Choi HN, Kim JH, Kim JI (2012) Quercetin ameliorates hyperglycemia and dyslipidemia and improves antioxidant status in type 2 diabetic db/db mice. Nutr Res Pract 6: 201-207.
    • (2012) Nutr Res Pract , vol.6 , pp. 201-207
    • Jeong, S.M.1    Kang, M.J.2    Choi, H.N.3    Kim, J.H.4    Kim, J.I.5
  • 17
    • 50649107938 scopus 로고    scopus 로고
    • Quercetin Ameliorates Metabolic Syndrome and Improves the Inflammatory Status in Obese Zucker Rats
    • Rivera L, Moron R, Sanchez M, Zarzuelo A, Galisteo M (2008) Quercetin Ameliorates Metabolic Syndrome and Improves the Inflammatory Status in Obese Zucker Rats. Obesity 16: 2081-2087.
    • (2008) Obesity , vol.16 , pp. 2081-2087
    • Rivera, L.1    Moron, R.2    Sanchez, M.3    Zarzuelo, A.4    Galisteo, M.5
  • 19
    • 59449098776 scopus 로고    scopus 로고
    • Failure of dietary quercetin to alter the temporal progression of insulin resistance among tissues of C57BL/6J mice during the development of diet-induced obesity
    • Stewart L, Wang Z, Ribnicky D, Soileau J, Cefalu W, et al. (2009) Failure of dietary quercetin to alter the temporal progression of insulin resistance among tissues of C57BL/6J mice during the development of diet-induced obesity. Diabetologia 52: 514-523.
    • (2009) Diabetologia , vol.52 , pp. 514-523
    • Stewart, L.1    Wang, Z.2    Ribnicky, D.3    Soileau, J.4    Cefalu, W.5
  • 20
    • 0345148810 scopus 로고    scopus 로고
    • Quercetin may act as a cytotoxic prooxidant after its metabolic activation to semiquinone and quinoidal product
    • Metodiewa D, Jaiswal AK, Cenas N, Dickancaite E, Segura-Aguilar J (1999) Quercetin may act as a cytotoxic prooxidant after its metabolic activation to semiquinone and quinoidal product. Free Radic Biol Med 26: 107-116.
    • (1999) Free Radic Biol Med , vol.26 , pp. 107-116
    • Metodiewa, D.1    Jaiswal, A.K.2    Cenas, N.3    Dickancaite, E.4    Segura-Aguilar, J.5
  • 22
    • 63949084185 scopus 로고    scopus 로고
    • The flavonoid quercetin induces changes in mitochondrial permeability by inhibiting adenine nucleotide translocase
    • Ortega R, García N (2009) The flavonoid quercetin induces changes in mitochondrial permeability by inhibiting adenine nucleotide translocase. Journal of Bioenergetics and Biomembranes 41: 41-47.
    • (2009) Journal of Bioenergetics and Biomembranes , vol.41 , pp. 41-47
    • Ortega, R.1    García, N.2
  • 24
    • 84864236699 scopus 로고    scopus 로고
    • Quercetin ameliorates hyperglycemia and dyslipidemia and improves antioxidant status in type 2 diabetic db/db mice
    • Jeong S-M, Kang M-J, Choi H-N, Kim J-H, Kim J-I (2012) Quercetin ameliorates hyperglycemia and dyslipidemia and improves antioxidant status in type 2 diabetic db/db mice. Nutr Res Pract 6: 201-207.
    • (2012) Nutr Res Pract , vol.6 , pp. 201-207
    • Jeong, S.-M.1    Kang, M.-J.2    Choi, H.-N.3    Kim, J.-H.4    Kim, J.-I.5
  • 25
    • 84864278991 scopus 로고    scopus 로고
    • Quercetin decreases inflammatory response and increases insulin action in skeletal muscle of ob/ob mice and in L6 myotubes
    • Anhê GF, Okamoto MM, Kinote A, Sollon C, Lellis-Santos C, et al. (2012) Quercetin decreases inflammatory response and increases insulin action in skeletal muscle of ob/ob mice and in L6 myotubes. European Journal of Pharmacology 689: 285-293.
    • (2012) European Journal of Pharmacology , vol.689 , pp. 285-293
    • Anhê, G.F.1    Okamoto, M.M.2    Kinote, A.3    Sollon, C.4    Lellis-Santos, C.5
  • 27
    • 34248140740 scopus 로고    scopus 로고
    • High-fat diet, muscular lipotoxicity and insulin resistance
    • Schrauwen P (2007) High-fat diet, muscular lipotoxicity and insulin resistance. Proceedings of the Nutrition Society 66: 33-41.
    • (2007) Proceedings of the Nutrition Society , vol.66 , pp. 33-41
    • Schrauwen, P.1
  • 28
    • 34547588219 scopus 로고    scopus 로고
    • Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle: Evidence against a role for reduced fatty acid oxidation in lipid-induced insulin resistance in rodents
    • DOI 10.2337/db07-0093
    • Turner N, Bruce CR, Beale SM, Hoehn KL, So T, et al. (2007) Excess Lipid Availability Increases Mitochondrial Fatty Acid Oxidative Capacity in Muscle: Evidence Against a Role for Reduced Fatty Acid Oxidation in Lipid-Induced Insulin Resistance in Rodents. Diabetes 56: 2085-2092. (Pubitemid 47195821)
    • (2007) Diabetes , vol.56 , Issue.8 , pp. 2085-2092
    • Turner, N.1    Bruce, C.R.2    Beale, S.M.3    Hoehn, K.L.4    So, T.5    Rolph, M.S.6    Cooney, G.J.7
  • 29
    • 34447511610 scopus 로고    scopus 로고
    • Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: Potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation
    • DOI 10.1074/jbc.M611214200
    • Crunkhorn S, Dearie F, Mantzoros C, Gami H, da Silva WS, et al. (2007) Peroxisome Proliferator Activator Receptor γ Coactivator-1 Expression Is Reduced in Obesity: Potential pathogenic role of saturated fatty acids and p38 mitogen porein kinase activation. Journal of Biological Chemistry 282: 15439-15450. (Pubitemid 47093279)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.21 , pp. 15439-15450
    • Crunkhorn, S.1    Dearie, F.2    Mantzoros, C.3    Gami, H.4    Da, S.W.S.5    Espinoza, D.6    Faucette, R.7    Barry, K.8    Bianco, A.C.9    Patti, M.E.10
  • 33
    • 84873696060 scopus 로고    scopus 로고
    • Quercetin ameliorate insulin resistance and up-regulates cellular antioxidants during oleic acid induced hepatic steatosis in HepG2 cells
    • Vidyashankar S, Sandeep Varma R, Patki PS (2013) Quercetin ameliorate insulin resistance and up-regulates cellular antioxidants during oleic acid induced hepatic steatosis in HepG2 cells. Toxicology in Vitro 27: 945-953.
    • (2013) Toxicology in Vitro , vol.27 , pp. 945-953
    • Vidyashankar, S.1    Sandeep Varma, R.2    Patki, P.S.3
  • 34
    • 77956094483 scopus 로고    scopus 로고
    • Increased Levels of Plasma Acylcarnitines in Obesity and Type 2 Diabetes and Identification of a Marker of Glucolipotoxicity
    • Mihalik SJ, Goodpaster BH, Kelley DE, Chace DH, Vockley J, et al. (2010) Increased Levels of Plasma Acylcarnitines in Obesity and Type 2 Diabetes and Identification of a Marker of Glucolipotoxicity. Obesity 18: 1695-1700.
    • (2010) Obesity , vol.18 , pp. 1695-1700
    • Mihalik, S.J.1    Goodpaster, B.H.2    Kelley, D.E.3    Chace, D.H.4    Vockley, J.5
  • 36
    • 79953232671 scopus 로고    scopus 로고
    • Exercise Increases Mitochondrial PGC-1α Content and Promotes Nuclear-Mitochondrial Cross-talk to Coordinate Mitochondrial Biogenesis
    • Safdar A, Little JP, Stokl AJ, Hettinga BP, Akhtar M, et al. (2011) Exercise Increases Mitochondrial PGC-1α Content and Promotes Nuclear-Mitochondrial Cross-talk to Coordinate Mitochondrial Biogenesis. Journal of Biological Chemistry 286: 10605-10617.
    • (2011) Journal of Biological Chemistry , vol.286 , pp. 10605-10617
    • Safdar, A.1    Little, J.P.2    Stokl, A.J.3    Hettinga, B.P.4    Akhtar, M.5
  • 37
    • 42449152466 scopus 로고    scopus 로고
    • Lipid-induced metabolic dysfunction in skeletal muscle
    • discussion 38-46, 162-163, 196-203
    • Muoio DM, Koves TR (2007) Lipid-induced metabolic dysfunction in skeletal muscle. Novartis Found Symp 286: 24-38; discussion 38-46, 162-163, 196-203.
    • (2007) Novartis Found Symp , vol.286 , pp. 24-38
    • Muoio, D.M.1    Koves, T.R.2
  • 39
    • 59649130350 scopus 로고    scopus 로고
    • Metabolic profiling of PPARα-/- mice reveals defects in carnitine and amino acid homeostasis that are partially reversed by oral carnitine supplementation
    • Makowski L, Noland RC, Koves TR, Xing W, Ilkayeva OR, et al. (2009) Metabolic profiling of PPARα-/- mice reveals defects in carnitine and amino acid homeostasis that are partially reversed by oral carnitine supplementation. The FASEB Journal 23: 586-604.
    • (2009) The FASEB Journal , vol.23 , pp. 586-604
    • Makowski, L.1    Noland, R.C.2    Koves, T.R.3    Xing, W.4    Ilkayeva, O.R.5
  • 40
    • 78650732495 scopus 로고    scopus 로고
    • Plasma Metabolomic Profiles Reflective of Glucose Homeostasis in Non-Diabetic and Type 2 Diabetic Obese African-American Women
    • Fiehn O, Garvey WT, Newman JW, Lok KH, Hoppel CL, et al. (2010) Plasma Metabolomic Profiles Reflective of Glucose Homeostasis in Non-Diabetic and Type 2 Diabetic Obese African-American Women. PLoS ONE 5: e15234. Medicine
    • (2010) PLoS ONE , vol.5
    • Fiehn, O.1    Garvey, W.T.2    Newman, J.W.3    Lok, K.H.4    Hoppel, C.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.