Downregulation of sFRP-2 by epigenetic silencing activates the β-catenin/Wnt signaling pathway in esophageal basaloid squamous cell carcinoma

Virchows Archiv

Volumn 464, Issue 2, 2014, Pages 135-143

  Saito, Tsuyoshi ^a   Mitomi, Hiroyuki ^a   Imamhasan, Abdukadir ^a   Hayashi, Takuo ^a   Mitani, Keiko ^a   Takahashi, Michiko ^a   Kajiyama, Yoshiaki ^a   Yao, Takashi ^a  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

catenin; Basaloid squamous cell carcinoma; Esophagus; Mutation; SFRP; Wnt

Indexed keywords

APC PROTEIN; AXIN1 PROTEIN; AXIN2 PROTEIN; BETA CATENIN; DICKKOPF 1 PROTEIN; HUMAN DAPPER PROTEIN 1; PROTEIN; SECRETED FRIZZLED RELATED PROTEIN 1; SECRETED FRIZZLED RELATED PROTEIN 2; SECRETED FRIZZLED RELATED PROTEIN 4; SECRETED FRIZZLED RELATED PROTEIN 5; UNCLASSIFIED DRUG; WNT INHIBITORY FACTOR 1;

ADULT; AGED; ARTICLE; CARCINOGENESIS; CLINICAL ARTICLE; CONTROLLED STUDY; DNA METHYLATION; DOWN REGULATION; EPIGENETICS; ESOPHAGEAL BASALOID SQUAMOUS CELL CARCINOMA; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; EXON; FEMALE; GENE SILENCING; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; MUTATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; SQUAMOUS EPITHELIUM; VERY ELDERLY; WNT SIGNALING PATHWAY;

AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; DNA METHYLATION; DNA MUTATIONAL ANALYSIS; DOWN-REGULATION; EPIGENESIS, GENETIC; ESOPHAGEAL NEOPLASMS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MEMBRANE PROTEINS; MIDDLE AGED; MUTATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; WNT SIGNALING PATHWAY;

EID: 84896734818     PISSN: 09456317     EISSN: 14322307     Source Type: Journal    
DOI: 10.1007/s00428-014-1538-1     Document Type: Article

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