Structure-based screening of inhibitors against KPC-2: Designing potential drug candidates against multidrug-resistant bacteria

Journal of Biomolecular Structure and Dynamics

Volumn 32, Issue 5, 2014, Pages 741-750

  Danishuddin, Mohd ^a   Khan, Arbab ^a   Faheem, Mohammad ^a   Kalaiarasan, Ponnusamy ^b   Hassan Baig, Mohd ^a   Subbarao, Naidu ^b   Khan, Asad U ^a  

^a ALIGARH MUSLIM UNIVERSITY   (India)

^b JAWAHARLAL NEHRU UNIVERSITY   (India)

Author keywords

cloning; docking; drug resistance; ESBL; KPC 2; molecular dynamics; PCR

Indexed keywords

AMIDOHYDROLASE INHIBITOR; ANTIBIOTIC AGENT; BETA LACTAMASE INHIBITOR; CEFOXITIN; CEFTAZIDIME; HYDROLASE INHIBITOR; UNCLASSIFIED DRUG; ZINC 01680846; ZINC 01807204; ZINC 02318494; ZINC 03861001; ZINC 06480725; ZINC 09212678; ANTIINFECTIVE AGENT; BETA LACTAMASE; BETA-LACTAMASE KPC-2; ENZYME INHIBITOR;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ARTICLE; BIOLOGICAL ACTIVITY; COMPUTER MODEL; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG IDENTIFICATION; DRUG SCREENING; DRUG STRUCTURE; ESCHERICHIA COLI; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MULTIDRUG RESISTANCE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; STRUCTURE ANALYSIS; CHEMISTRY; COMPUTER SIMULATION; DRUG DESIGN; DRUG EFFECTS; GENETICS; MICROBIAL SENSITIVITY TEST; MUTATION; STRUCTURE ACTIVITY RELATION;

ANTI-BACTERIAL AGENTS; BETA-LACTAMASES; COMPUTER SIMULATION; DRUG DESIGN; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ENZYME INHIBITORS; ESCHERICHIA COLI; MICROBIAL SENSITIVITY TESTS; MOLECULAR DOCKING SIMULATION; MOLECULAR DYNAMICS SIMULATION; MUTATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84896729508     PISSN: 07391102     EISSN: 15380254     Source Type: Journal    
DOI: 10.1080/07391102.2013.789988     Document Type: Article

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