Elucidating the role of Trp105 in the KPC-2 β-lactamase

Protein Science

Volumn 19, Issue 9, 2010, Pages 1714-1727

  Papp Wallace, Krisztina M ^a,b   Taracila, Magdalena ^a,b   Wallace, Christopher J ^a,b   Hujer, Kristine M ^a,b   Bethel, Christopher R ^b   Hornick, John M ^b   Bonomo, Robert A ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

Author keywords

lactamase; Carbapenem discrimination; Carbapenemase; Clavulanic acid; KPC 2

Indexed keywords

AMPICILLIN; ASPARAGINE; BETA LACTAMASE; CEFALOTIN; CEFOTAXIME; CLAVULANIC ACID; DORIPENEM; ENZYME; ERTAPENEM; HISTIDINE; IMIPENEM; KPC 2 BETA LACTAMASE; LEUCINE; MEROPENEM; NITROCEFIN; PHENYLALANINE; PIPERACILLIN; PIPERACILLIN PLUS TAZOBACTAM; SULBACTAM; SULTAMICILLIN; TAZOBACTAM; TRYPTOPHAN; TYROSINE; UNCLASSIFIED DRUG; VALINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL CELL; CATALYSIS; CHEMICAL ANALYSIS; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME STRUCTURE; ENZYME SUBSTRATE; ESCHERICHIA COLI; GENETIC VARIABILITY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PARTITION COEFFICIENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS; WILD TYPE;

ANTI-BACTERIAL AGENTS; BETA-LACTAMASES; CARBAPENEMS; CEPHALOSPORINS; ESCHERICHIA COLI; GENE EXPRESSION; MICROBIAL SENSITIVITY TESTS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MUTAGENESIS, SITE-DIRECTED; PENICILLINS; TRYPTOPHAN;

ESCHERICHIA COLI;

EID: 77956370566     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.454     Document Type: Article

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