-
1
-
-
80053563923
-
Misfolded protein aggregates: Mechanisms, structures and potential for disease transmission
-
Moreno-Gonzalez I, Soto C (2011) Misfolded protein aggregates: mechanisms, structures and potential for disease transmission. Semin Cell Dev Biol 22: 482-487.
-
(2011)
Semin Cell Dev Biol
, vol.22
, pp. 482-487
-
-
Moreno-Gonzalez, I.1
Soto, C.2
-
2
-
-
78650031174
-
Huntington's disease: From molecular pathogenesis to clinical treatment
-
Ross CA, Tabrizi SJ (2011) Huntington's disease: from molecular pathogenesis to clinical treatment. Lancet Neurol 10: 83-98.
-
(2011)
Lancet Neurol
, vol.10
, pp. 83-98
-
-
Ross, C.A.1
Tabrizi, S.J.2
-
3
-
-
81055144784
-
Autophagy: Renovation of cells and tissues
-
Mizushima N, Komatsu M (2011) Autophagy: renovation of cells and tissues. Cell 147: 728-741.
-
(2011)
Cell
, vol.147
, pp. 728-741
-
-
Mizushima, N.1
Komatsu, M.2
-
4
-
-
84877628647
-
Autophagy in human health and disease
-
Choi AM, Ryter SW, Levine B (2013) Autophagy in human health and disease. N Engl J Med 368: 651-662.
-
(2013)
N Engl J Med
, vol.368
, pp. 651-662
-
-
Choi, A.M.1
Ryter, S.W.2
Levine, B.3
-
5
-
-
33750363298
-
The roles of intracellular protein-degradation pathways in neurodegeneration
-
Rubinsztein DC (2006) The roles of intracellular protein-degradation pathways in neurodegeneration. Nature 443: 780-786.
-
(2006)
Nature
, vol.443
, pp. 780-786
-
-
Rubinsztein, D.C.1
-
7
-
-
34848886914
-
Autophagosome formation: Core machinery and adaptations
-
Xie Z, Klionsky DJ (2007) Autophagosome formation: core machinery and adaptations. Nat Cell Biol 9: 1102-1109.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 1102-1109
-
-
Xie, Z.1
Klionsky, D.J.2
-
8
-
-
1242272754
-
Diversity of the mammalian sodium/proton exchanger SLC9 gene family
-
Orlowski J, Grinstein S (2004) Diversity of the mammalian sodium/proton exchanger SLC9 gene family. Eur J Physiol 447: 549-565.
-
(2004)
Eur J Physiol
, vol.447
, pp. 549-565
-
-
Orlowski, J.1
Grinstein, S.2
-
9
-
-
0033054555
-
Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin
-
Schilling G, Becher MW, Sharp AH, Jinnah HA, Duan K, et al. (1999) Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin. Hum Mol Genet 8: 397-407.
-
(1999)
Hum Mol Genet
, vol.8
, pp. 397-407
-
-
Schilling, G.1
Becher, M.W.2
Sharp, A.H.3
Jinnah, H.A.4
Duan, K.5
-
10
-
-
0034615932
-
Inhibition of polyglutamine protein aggregation and cell death by novel peptides identified by phage display screening
-
Nagai Y, Tucker T, Ren H, Kenan DJ, Henderson BS, et al. (2000) Inhibition of polyglutamine protein aggregation and cell death by novel peptides identified by phage display screening. J Biol Chem 275: 10437-10442.
-
(2000)
J Biol Chem
, vol.275
, pp. 10437-10442
-
-
Nagai, Y.1
Tucker, T.2
Ren, H.3
Kenan, D.J.4
Henderson, B.S.5
-
11
-
-
80052145606
-
A sensitive and quantitative technique for detecting autophagic events based on lysosomal delivery
-
Katayama H, Kogure T, Mizushima N, Yoshimori T, Miyawaki A (2011) A sensitive and quantitative technique for detecting autophagic events based on lysosomal delivery. Chem Biol 18: 1042-1052.
-
(2011)
Chem Biol
, vol.18
, pp. 1042-1052
-
-
Katayama, H.1
Kogure, T.2
Mizushima, N.3
Yoshimori, T.4
Miyawaki, A.5
-
12
-
-
57449100300
-
Intracellular alkalization causes pain sensation through activation of TRPA1 in mice
-
Fujita F, Uchida K, Moriyama T, Shima A, Shibasaki K, et al. (2008) Intracellular alkalization causes pain sensation through activation of TRPA1 in mice. J Clin Invest 118: 4049-4057.
-
(2008)
J Clin Invest
, vol.118
, pp. 4049-4057
-
-
Fujita, F.1
Uchida, K.2
Moriyama, T.3
Shima, A.4
Shibasaki, K.5
-
13
-
-
0018764575
-
Intracellular pH measurements in Ehrlich ascites tumor cells utilizing spectroscopic probes generated in situ
-
Thomas JA, Buchsbaum RN, Zimniak A, Racker E (1979) Intracellular pH measurements in Ehrlich ascites tumor cells utilizing spectroscopic probes generated in situ. Biochemistry 18: 2210-228.
-
(1979)
Biochemistry
, vol.18
, pp. 2210-2228
-
-
Thomas, J.A.1
Buchsbaum, R.N.2
Zimniak, A.3
Racker, E.4
-
14
-
-
33646543034
-
TRPM2 activation by cyclic ADP-ribose at body temperature is involved in insulin secretion
-
Togashi K, Hara Y, Tominaga T, Higashi T, Konishi Y, et al. (2006) TRPM2 activation by cyclic ADP-ribose at body temperature is involved in insulin secretion. Embo J 25: 1804-1815.
-
(2006)
Embo J
, vol.25
, pp. 1804-1815
-
-
Togashi, K.1
Hara, Y.2
Tominaga, T.3
Higashi, T.4
Konishi, Y.5
-
15
-
-
1542283812
-
In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker
-
Mizushima N, Yamamoto A, Matsui M, Yoshimori T, Ohsumi Y (2004) In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol Biol Cell 15: 1101-1111.
-
(2004)
Mol Biol Cell
, vol.15
, pp. 1101-1111
-
-
Mizushima, N.1
Yamamoto, A.2
Matsui, M.3
Yoshimori, T.4
Ohsumi, Y.5
-
16
-
-
8344242220
-
Autophagy in health and disease: A double-edged sword
-
Shintani T, Klionsky DJ (2004) Autophagy in health and disease: a double-edged sword. Science 306: 990-995.
-
(2004)
Science
, vol.306
, pp. 990-995
-
-
Shintani, T.1
Klionsky, D.J.2
-
17
-
-
33750385331
-
Transporters involved in regulation of intracellular pH in primary cultured rat brain endothelial cells
-
Taylor CJ, Nicola PA, Wang S, Barrand MA, Hladky SB (2006) Transporters involved in regulation of intracellular pH in primary cultured rat brain endothelial cells. J Physiol 576: 769-785.
-
(2006)
J Physiol
, vol.576
, pp. 769-785
-
-
Taylor, C.J.1
Nicola, P.A.2
Wang, S.3
Barrand, M.A.4
Hladky, S.B.5
-
18
-
-
54749103155
-
New light on the "old" chloride channel blocker DIDS
-
Wulff H (2008) New light on the "old" chloride channel blocker DIDS. ACS Chem Biol 3: 399-401.
-
(2008)
ACS Chem Biol
, vol.3
, pp. 399-401
-
-
Wulff, H.1
-
19
-
-
0038121757
-
An overview of inhibitors of Na(+)/H(+) exchanger
-
Masereel B, Pochet L, Laeckmann D (2003) An overview of inhibitors of Na(+)/H(+) exchanger. Eur J Med Chem 38: 547-554.
-
(2003)
Eur J Med Chem
, vol.38
, pp. 547-554
-
-
Masereel, B.1
Pochet, L.2
Laeckmann, D.3
-
20
-
-
84862295360
-
Guidelines for the use and interpretation of assays for monitoring autophagy
-
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, et al. (2012) Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 8: 445-544.
-
(2012)
Autophagy
, vol.8
, pp. 445-544
-
-
Klionsky, D.J.1
Abdalla, F.C.2
Abeliovich, H.3
Abraham, R.T.4
Acevedo-Arozena, A.5
-
21
-
-
0034503095
-
Direct binding of the Na - H exchanger NHE1 to ERM proteins regulates the cortical cytoskeleton and cell shape independently of H(+) translocation
-
Denker SP, Huang DC, Orlowski J, Furthmayr H, Barber DL (2000) Direct binding of the Na - H exchanger NHE1 to ERM proteins regulates the cortical cytoskeleton and cell shape independently of H(+) translocation. Mol Cell 6: 1425-1436.
-
(2000)
Mol Cell
, vol.6
, pp. 1425-1436
-
-
Denker, S.P.1
Huang, D.C.2
Orlowski, J.3
Furthmayr, H.4
Barber, D.L.5
-
22
-
-
79959659943
-
Regulation of dendritic spine growth through activity-dependent recruitment of the brain-enriched Na(+)/H(+) exchanger NHE5
-
Diering GH, Mills F, Bamji SX, Numata M (2011) Regulation of dendritic spine growth through activity-dependent recruitment of the brain-enriched Na(+)/H(+) exchanger NHE5. Mol Biol Cell 22: 2246-2257.
-
(2011)
Mol Biol Cell
, vol.22
, pp. 2246-2257
-
-
Diering, G.H.1
Mills, F.2
Bamji, S.X.3
Numata, M.4
-
23
-
-
53349127249
-
Blocking acid-sensing ion channel 1 alleviates Huntington's disease pathology via an ubiquitin-proteasome system-dependent mechanism
-
Wong HK, Bauer PO, Kurosawa M, Goswami A, Washizu C, et al. (2008) Blocking acid-sensing ion channel 1 alleviates Huntington's disease pathology via an ubiquitin-proteasome system-dependent mechanism. Hum Mol Genet 17: 3223-3235.
-
(2008)
Hum Mol Genet
, vol.17
, pp. 3223-3235
-
-
Wong, H.K.1
Bauer, P.O.2
Kurosawa, M.3
Goswami, A.4
Washizu, C.5
-
24
-
-
24944482408
-
Increased susceptibility of cytoplasmic over nuclear polyglutamine aggregates to autophagic degradation
-
Iwata A, Christianson JC, Bucci M, Ellerby LM, Nukina N, et al. (2005) Increased susceptibility of cytoplasmic over nuclear polyglutamine aggregates to autophagic degradation. Proc Natl Acad Sci U S A 102: 13135-13140.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 13135-13140
-
-
Iwata, A.1
Christianson, J.C.2
Bucci, M.3
Ellerby, L.M.4
Nukina, N.5
-
25
-
-
0032954796
-
Targeted disruption of the murine Nhe1 locus induces ataxia, growth retardation, and seizures
-
Bell SM, Schreiner CM, Schultheis PJ, Miller ML, Evans RL, et al. (1999) Targeted disruption of the murine Nhe1 locus induces ataxia, growth retardation, and seizures. Am J Physiol 276: C788-795.
-
(1999)
Am J Physiol
, vol.276
-
-
Bell, S.M.1
Schreiner, C.M.2
Schultheis, P.J.3
Miller, M.L.4
Evans, R.L.5
-
26
-
-
0030886101
-
Sodium/hydrogen exchanger gene defect in slow-wave epilepsy mutant mice
-
Cox GA, Lutz CM, Yang CL, Biemesderfer D, Bronson RT, et al. (1997) Sodium/hydrogen exchanger gene defect in slow-wave epilepsy mutant mice. Cell 91: 139-148.
-
(1997)
Cell
, vol.91
, pp. 139-148
-
-
Cox, G.A.1
Lutz, C.M.2
Yang, C.L.3
Biemesderfer, D.4
Bronson, R.T.5
-
27
-
-
33745684313
-
Physiology and pathophysiology of Na +/H+ exchange and Na+ -K+ -2Cl- cotransport in the heart, brain, and blood
-
Pedersen SF, O'Donnell ME, Anderson SE, Cala PM (2006) Physiology and pathophysiology of Na +/H+ exchange and Na+ -K+ -2Cl- cotransport in the heart, brain, and blood. Am J Physiol Regul Integr Comp Physiol 291: R1-25.
-
(2006)
Am J Physiol Regul Integr Comp Physiol
, vol.291
-
-
Pedersen, S.F.1
O'Donnell, M.E.2
Anderson, S.E.3
Cala, P.M.4
|