The effects of actin cytoskeleton perturbation on keratin intermediate filament formation in mesenchymal stem/stromal cells

Biomaterials

Volumn 35, Issue 13, 2014, Pages 3934-3944

  Chang, Tzu Hao ^a   Huang, Hsien Da ^b   Ong, Wei Kee ^c   Fu, Yun Ju ^c   Lee, Oscar K ^d   Chien, Shu ^e,f   Ho, Jennifer H ^a,c  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL CHIAO TUNG UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d NATIONAL YANG MING UNIVERSITY   (Taiwan)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Chromosome 17q21.2; F actin depolymerization; Intermediate filaments; Keratin; Mesenchymal stem cells (MSCs); NK2 homeobox 5 (NKX2.5)

Indexed keywords

ACTIN CYTOSKELETON; DIFFERENTIAL GENE EXPRESSIONS; F-ACTIN; FUNCTIONAL ENRICHMENT ANALYSIS; INTERMEDIATE FILAMENTS; MESENCHYMAL STEM CELL; MORPHOLOGICAL CHANGES; NK2 HOMEOBOX 5 (NKX2.5);

CELL CULTURE; FLOWCHARTING; GENES; SCAFFOLDS (BIOLOGY); TRANSCRIPTION FACTORS;

KERATIN;

ADP RIBOSYLATION FACTOR LIKE 4C; ALDEHYDE DEHYDROGENASE 1 FAMILY MEMBER A3; CYTOKERATIN 14; CYTOKERATIN 19; EPIREGULIN; F ACTIN; FAMILY WITH SEQUENCE SIMILARITY 149 MEMBER A; FAMILY WITH SEQUENCE SIMILARITY 43 MEMBER A; FC RECEPTOR LIKE B; GLUTATHIONE PEROXIDASE 7; HEN1 METHYLTRANSFERASE HOMOLOG 1; HISTIDINE TRIAD NUCLEOTIDE BINDING PROTEIN 3; HISTONE CLUSTER 1; INTERSTITIAL COLLAGENASE; KERATIN; KERATIN 34; KERATIN ASSOCIATED PROTEIN 1-5; KERATIN ASSOCIATED PROTEIN 2-3; LATRUNCULIN B; MELANOCORTIN 2 RECEPTOR ACCESSORY PROTEIN 2; MICROTUBULE ASSOCIATED SERINE THREONINE KINASE FAMILY MEMBER 4; NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 3; OCIA DOMAIN CONTAINING 2; OXIDATIVE STRESS RESPONSIVE 1; PREGNANCY SPECIFIC BETA1 GLYCOPROTEIN 5; PROSTAGLANDIN E SYNTHASE; RAB 27B PROTEIN; RAS HOMOLOG FAMILY MEMBER U; TRANSCRIPTION FACTOR NKX2.5; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG; FUSED HETEROCYCLIC RINGS; THIAZOLIDINE DERIVATIVE;

ACTIN FILAMENT; ARTICLE; CELL SHAPE; CHROMOSOME 17Q; CONTROLLED STUDY; DEPOLYMERIZATION; DOWN REGULATION; GENE CONTROL; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; MESENCHYMAL STEM CELL; MICROARRAY ANALYSIS; MOLECULAR INTERACTION; PRIORITY JOURNAL; STROMA CELL; UPREGULATION; CELL CULTURE; DRUG EFFECTS; INTERMEDIATE FILAMENT; MESENCHYMAL STROMA CELL; METABOLISM;

ACTIN CYTOSKELETON; BICYCLO COMPOUNDS, HETEROCYCLIC; CELLS, CULTURED; HUMANS; INTERMEDIATE FILAMENTS; KERATINS; MESENCHYMAL STROMAL CELLS; THIAZOLIDINES;

EID: 84896721884     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.01.028     Document Type: Article

References (57)

1. Wang Y.L. Dynamics of the cytoskeleton in live cells. Curr Opin Cell Biol 1991, 3:27-32.
2. Vignaud T., Blanchoin L., Thery M. Directed cytoskeleton self-organization. Trends Cell Biol 2012, 22:671-682.
3. Brakebusch C., Fassler R. The integrin-actin connection, an eternal love affair. EMBO J 2003, 22:2324-2333.
4. Brieher W.M., Yap A.S. Cadherin junctions and their cytoskeleton(s). Curr Opin Cell Biol 2013, 25:39-46.
5. Galkin V.E., Orlova A., Egelman E.H. Actin filaments as tension sensors. Curr Biol 2012, 22:R96-R101.
6. Patwari P., Lee R.T. Mechanical control of tissue morphogenesis. Circ Res 2008, 103:234-243.
7. Attia M., Santerre J.P., Kandel R.A. The response of annulus fibrosus cell to fibronectin-coated nanofibrous polyurethane-anionic dihydroxyoligomer scaffolds. Biomaterials 2011, 32:450-460.
8. Schagemann J.C., Kurz H., Casper M.E., Stone J.S., Dadsetan M., Yu-Long S., et al. The effect of scaffold composition on the early structural characteristics of chondrocytes and expression of adhesion molecules. Biomaterials 2010, 31:2798-2805.
9. Coue M., Brenner S.L., Spector I., Korn E.D. Inhibition of actin polymerization by latrunculin A. FEBS Lett 1987, 213:316-318.
10. Morton W.M., Ayscough K.R., McLaughlin P.J. Latrunculin alters the actin-monomer subunit interface to prevent polymerization. Nat Cell Biol 2000, 2:376-378.
11. Spector I., Shochet N.R., Blasberger D., Kashman Y. Latrunculins-novel marine macrolides that disrupt microfilament organization and affect cell growth: I. Comparison with cytochalasin D. Cell Motil Cytoskeleton 1989, 13:127-144.
12. Herzog E.L., Chai L., Krause D.S. Plasticity of marrow-derived stem cells. Blood 2003, 102:3483-3493.
13. Dominici M., Le Blanc K., Mueller I., Slaper-Cortenbach I., Marini F., Krause D., et al. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy 2006, 8:315-317.
14. Kuo S.W., Lin H.I., Ho J.H., Shih Y.R., Chen H.F., Yen T.J., et al. Regulation of the fate of human mesenchymal stem cells by mechanical and stereo-topographical cues provided by silicon nanowires. Biomaterials 2012, 33:5013-5022.
15. Kang Y., Kim S., Khademhosseini A., Yang Y. Creation of bony microenvironment with CaP and cell-derived ECM to enhance human bone-marrow MSC behavior and delivery of BMP-2. Biomaterials 2011, 32:6119-6130.
16. Costa P., Almeida F.V., Connelly J.T. Biophysical signals controlling cell fate decisions: how do stem cells really feel?. Int J Biochem Cell Biol 2012, 44:2233-2237.
17. Maloney J.M., Nikova D., Lautenschlager F., Clarke E., Langer R., Guck J., et al. Mesenchymal stem cell mechanics from the attached to the suspended state. Biophys J 2010, 99:2479-2487.
18. Ho J.H., Ma W.H., Su Y., Tseng K.C., Kuo T.K., Lee O.K. Thymosin beta-4 directs cell fate determination of human mesenchymal stem cells through biophysical effects. JOrthop Res 2010, 28:131-138.
19. Rodriguez J.P., Gonzalez M., Rios S., Cambiazo V. Cytoskeletal organization of human mesenchymal stem cells (MSC) changes during their osteogenic differentiation. JCell Biochem 2004, 93:721-731.
20. Mathieu P.S., Loboa E.G. Cytoskeletal and focal adhesion influences on mesenchymal stem cell shape, mechanical properties, and differentiation down osteogenic, adipogenic, and chondrogenic pathways. Tissue Eng Part B Rev 2012, 18:436-444.
21. Shi J.W., Liu W., Zhang T.T., Wang S.C., Lin X.L., Li J., et al. The enforced expression of c-Myc in pig fibroblasts triggers mesenchymal-epithelial transition (MET) via F-actin reorganization and RhoA/Rock pathway inactivation. Cell Cycle 2013, 12:1119-1127.
22. Ho J.H., Ma W.H., Tseng T.C., Chen Y.F., Chen M.H., Lee O.K. Isolation and characterization of multi-potent stem cells from human orbital fat tissues. Tissue Eng Part A 2011, 17:255-266.
23. Schneider C.A., Rasband W.S., Eliceiri K.W. NIH Image to ImageJ: 25 years of image analysis. Nat Methods 2012, 9:671-675.
24. Gentleman CPaCHaR. affyQCReport: QC report generation for affyBatch objects 2005.
25. Gautier L., Cope L., Bolstad B.M., Irizarry R.A. affy-analysis of Affymetrix GeneChip data at the probe level. Bioinformatics 2004, 20:307-315.
26. Dennis G., Sherman B.T., Hosack D.A., Yang J., Gao W., Lane H.C., et al. DAVID: database for Annotation, Visualization, and Integrated discovery. Genome Biol 2003, 4:P3.
27. Gourlay C.W., Ayscough K.R. The actin cytoskeleton: a key regulator of apoptosis and ageing?. Nat Rev Mol Cell Biol 2005, 6:583-589.
28. Ong W.K., Chen H.F., Tsai C.T., Fu Y.J., Wong Y.S., Yen D.J., et al. The activation of directional stem cell motility by green light-emitting diode irradiation. Biomaterials 2013, 34:1911-1920.
29. Nakano K., Takaishi K., Kodama A., Mammoto A., Shiozaki H., Monden M., et al. Distinct actions and cooperative roles of ROCK and mDia in Rho small G protein-induced reorganization of the actin cytoskeleton in Madin-Darby canine kidney cells. Mol Biol Cell 1999, 10:2481-2491.
30. Esparza J., Vilardell C., Calvo J., Juan M., Vives J., Urbano-Marquez A., et al. Fibronectin upregulates gelatinase B (MMP-9) and induces coordinated expression of gelatinase A (MMP-2) and its activator MT1-MMP (MMP-14) by human T lymphocyte cell lines. A process repressed through RAS/MAP kinase signaling pathways. Blood 1999, 94:2754-2766.
31. Jin E.J., Park K.S., Bang O.S., Kang S.S. Akt signaling regulates actin organization via modulation of MMP-2 activity during chondrogenesis of chick wing limb bud mesenchymal cells. JCell Biochem 2007, 102:252-261.
32. Leinweber B.D., Leavis P.C., Grabarek Z., Wang C.L., Morgan K.G. Extracellular regulated kinase (ERK) interaction with actin and the calponin homology (CH) domain of actin-binding proteins. Biochem J 1999, 344(Pt 1):117-123.
33. Haines R.L., Lane E.B. Keratins and disease at a glance. JCell Sci 2012, 125:3923-3928.
34. Herrmann H., Bar H., Kreplak L., Strelkov S.V., Aebi U. Intermediate filaments: from cell architecture to nanomechanics. Nat Rev Mol Cell Biol 2007, 8:562-573.
35. Goldman R.D., Cleland M.M., Murthy S.N., Mahammad S., Kuczmarski E.R. Inroads into the structure and function of intermediate filament networks. JStruct Biol 2012, 177:14-23.
36. Eriksson J.E., Dechat T., Grin B., Helfand B., Mendez M., Pallari H.M., et al. Introducing intermediate filaments: from discovery to disease. JClin Invest 2009, 119:1763-1771.
37. Chang L., Goldman R.D. Intermediate filaments mediate cytoskeletal crosstalk. Nat Rev Mol Cell Biol 2004, 5:601-613.
38. Windoffer R., Beil M., Magin T.M., Leube R.E. Cytoskeleton in motion: the dynamics of keratin intermediate filaments in epithelia. JCell Biol 2011, 194:669-678.
39. Sergi C., Abdualmjid R., Abuetabh Y. Canine liver transplantation model and the intermediate filaments of the cytoskeleton of the hepatocytes. JBiomed Biotechnol 2012, 2012:131324.
40. Reichelt J., Bussow H., Grund C., Magin T.M. Formation of a normal epidermis supported by increased stability of keratins 5 and 14 in keratin 10 null mice. Mol Biol Cell 2001, 12:1557-1568.
41. Joseph A., Powell-Richards A.O., Shanmuganathan V.A., Dua H.S. Epithelial cell characteristics of cultured human limbal explants. Br J Ophthalmol 2004, 88:393-398.
42. Kloepper J.E., Tiede S., Brinckmann J., Reinhardt D.P., Meyer W., Faessler R., et al. Immunophenotyping of the human bulge region: the quest to define useful in situ markers for human epithelial hair follicle stem cells and their niche. Exp Dermatol 2008, 17:592-609.
43. Haque S., Haruna Y., Saito K., Nalesnik M.A., Atillasoy E., Thung S.N., et al. Identification of bipotential progenitor cells in human liver regeneration. Lab Invest 1996, 75:699-705.
44. Schweizer J., Bowden P.E., Coulombe P.A., Langbein L., Lane E.B., Magin T.M., et al. New consensus nomenclature for mammalian keratins. JCell Biol 2006, 174:169-174.
45. Rogers G.E. Hair follicle differentiation and regulation. Int J Dev Biol 2004, 48:163-170.
46. Gong H., Zhou H., McKenzie G.W., Yu Z., Clerens S., Dyer J.M., et al. An updated nomenclature for keratin-associated proteins (KAPs). Int J Biol Sci 2012, 8:258-264.
47. Sasaki M., Abe R., Fujita Y., Ando S., Inokuma D., Shimizu H. Mesenchymal stem cells are recruited into wounded skin and contribute to wound repair by transdifferentiation into multiple skin cell type. JImmunol 2008, 180:2581-2587.
48. Sivamani R.K., Schwartz M.P., Anseth K.S., Isseroff R.R. Keratinocyte proximity and contact can play a significant role in determining mesenchymal stem cell fate in human tissue. FASEB J 2011, 25:122-131.
49. Wu Y., Chen L., Scott P.G., Tredget E.E. Mesenchymal stem cells enhance wound healing through differentiation and angiogenesis. Stem Cells 2007, 25:2648-2659.
50. Aljitawi O.S., Xiao Y., Zhang D., Stehno-Bittel L., Garimella R., Hopkins R.A., et al. Generating CK19-positive cells with hair-like structures from Wharton's jelly mesenchymal stromal cells. Stem Cells Dev 2013, 22:18-26.
51. Hwang S., Hong H.N., Kim H.S., Park S.R., Won Y.J., Choi S.T., et al. Hepatogenic differentiation of mesenchymal stem cells in a rat model of thioacetamide-induced liver cirrhosis. Cell Biol Int 2012, 36:279-288.
52. Rogers M.A., Winter H., Langbein L., Bleiler R., Schweizer J. The human type I keratin gene family: characterization of new hair follicle specific members and evaluation of the chromosome 17q21.2 gene domain. Differentiation 2004, 72:527-540.
53. Durocher D., Charron F., Warren R., Schwartz R.J., Nemer M. The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors. EMBO J 1997, 16:5687-5696.
54. Reamon-Buettner S.M., Borlak J. NKX2-5: an update on this hypermutable homeodomain protein and its role in human congenital heart disease (CHD). Hum Mutat 2010, 31:1185-1194.
55. Nettore I.C., Cacace V., De Fusco C., Colao A., Macchia P.E. The molecular causes of thyroid dysgenesis: a systematic review. JEndocrinol Invest 2013, 36:654-664.
56. Arminan A., Gandia C., Bartual M., Garcia-Verdugo J.M., Lledo E., Mirabet V., et al. Cardiac differentiation is driven by NKX2.5 and GATA4 nuclear translocation in tissue-specific mesenchymal stem cells. Stem Cells Dev 2009, 18:907-918.
57. Riazi A.M., Lee H., Hsu C., Van Arsdell G. CSX/Nkx2.5 modulates differentiation of skeletal myoblasts and promotes differentiation into neuronal cells invitro. JBiol Chem 2005, 280:10716-10720.