Cardiac-specific adipose triglyceride lipase overexpression protects from cardiac steatosis and dilated cardiomyopathy following diet-induced obesity

International Journal of Obesity

Volumn 38, Issue 2, 2014, Pages 205-215

  Pulinilkunnil, T ^a   Kienesberger, P C ^a   Nagendran, J ^a   Sharma, N ^a   Young, M E ^b   Dyck, J R B ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b and Clinical Center   (United States)

Author keywords

ATGL; cardiomyopathy; energy metabolism; lipolysis; triacylglycerol; western diet

Indexed keywords

ADIPOSE TRIGLYCERIDE LIPASE; COLLAGEN TYPE 1; GLUCOSE; GLUCOSE TRANSPORTER 1; GLUCOSE TRANSPORTER 4; INSULIN; LONG CHAIN FATTY ACID COENZYME A LIGASE; MITOCHONDRIAL TRANSCRIPTION FACTOR A; NUCLEAR RESPIRATORY FACTOR 1; PALMITIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; TRIACYLGLYCEROL; TRIACYLGLYCEROL LIPASE; TROPONIN I; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 3; FAT; SUCROSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CARDIAC STEATOSIS; CATABOLISM; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; DIASTOLIC DYSFUNCTION; FATTY ACID OXIDATION; FATTY ACID TRANSPORT; GLUCOSE BLOOD LEVEL; GLUCOSE OXIDATION; HEART FUNCTION; HEART MUSCLE CELL; HEART PERFUSION; HEART PROTECTION; HYDROLYSIS; IN VIVO STUDY; INSULIN RESISTANCE; INSULIN TOLERANCE TEST; LIPID DIET; LIPID STORAGE; LIPOLYSIS; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STEATOSIS; SYSTOLIC DYSFUNCTION; TRANSTHORACIC ECHOCARDIOGRAPHY; ANIMAL TISSUE; CHEMICAL ANALYSIS; DIET; EX VIVO STUDY; GENE OVEREXPRESSION; GENOTYPE; HEART DILATATION; MALE; UPREGULATION; WILD TYPE;

MUS;

ADIPOSE TISSUE; ANIMALS; CARDIOMYOPATHY, DILATED; DIET, HIGH-FAT; ELECTROCARDIOGRAPHY; ENERGY METABOLISM; HEART DISEASES; INSULIN RESISTANCE; LIPID METABOLISM; LIPID PEROXIDATION; MICE; MICE, OBESE; MYOCARDIUM; MYOCYTES, CARDIAC; OBESITY; RISK FACTORS; TRIGLYCERIDES;

EID: 84896715505     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2013.103     Document Type: Article

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