N-Acetylcysteine prevents congenital heart defects induced by pregestational diabetes

Cardiovascular Diabetology

Volumn 13, Issue 1, 2014, Pages

  Moazzen, Hoda ^a   Lu, Xiangru ^a   Ma, Noelle L ^a   Velenosi, Thomas J ^a   Urquhart, Brad L ^a,b,c   Wisse, Lambertus J ^d   Gittenberger de Groot, Adriana C ^d   Feng, Qingping ^a,b,c  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b Department of Medicine ^*  (Canada)

^c LAWSON HEALTH RESEARCH INSTITUTE   (Canada)

^d LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Congenital heart defects; Glutathione; N acetylcysteine; Pregestational diabetes; Reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; GLUCOSE; GLUTATHIONE; REACTIVE OXYGEN METABOLITE; STREPTOZOCIN; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR GATA 5; VASCULOTROPIN A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ATRIOVENTRICULAR SEPTAL DEFECT; BODY WEIGHT; CELL PROLIFERATION; COMPARATIVE STUDY; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; DIABETES MELLITUS; EMBRYO; ENDOCARDIAL CUSHION; FALLOT TETRALOGY; FEMALE; FETUS HEART; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; GLUTATHIONE METABOLISM; GREAT VESSELS TRANSPOSITION; HEART ATRIUM SEPTUM DEFECT; HEART RIGHT VENTRICLE DOUBLE OUTLET; HEART VENTRICLE SEPTUM DEFECT; MATERNAL BLOOD; MATERNAL DIABETES MELLITUS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PREGESTATIONAL DIABETES; PROGENY; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS;

ACETYLCYSTEINE; ANIMALS; BLOOD GLUCOSE; CARDIOTONIC AGENTS; DIABETES MELLITUS, EXPERIMENTAL; FEMALE; HEART DEFECTS, CONGENITAL; MALE; MICE; MICE, INBRED C57BL; PREGNANCY; PREGNANCY IN DIABETICS;

EID: 84896707655     PISSN: None     EISSN: 14752840     Source Type: Journal    
DOI: 10.1186/1475-2840-13-46     Document Type: Article

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