An excess of deleterious variants in VEGF-A pathway genes in down-syndrome-associated atrioventricular septal defects

American Journal of Human Genetics

Volumn 91, Issue 4, 2012, Pages 646-659

  Ackerman, Christine ^a   Locke, Adam E ^b   Feingold, Eleanor ^c   Reshey, Benjamin ^a   Espana, Karina ^a   Thusberg, Janita ^d   Mooney, Sean ^d   Bean, Lora J H ^b   Dooley, Kenneth J ^b   Cua, Clifford L ^e   Reeves, Roger H ^f   Sherman, Stephanie L ^b   Maslen, Cheryl L ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^d BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^e NATIONWIDE CHILDREN S HOSPITAL   (United States)

^f JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VASCULOTROPIN A;

ARTICLE; ATRIOVENTRICULAR SEPTAL DEFECT; COL6A1 GENE; COL6A2 GENE; CONTROLLED STUDY; CRELD1 GENE; DOWN SYNDROME; FBLN2 GENE; FRZB GENE; GATA5 GENE; GENE; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; MORPHOGENESIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

CASE-CONTROL STUDIES; DOWN SYNDROME; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; HEART SEPTAL DEFECTS, ATRIAL; HEART SEPTAL DEFECTS, VENTRICULAR; HUMANS; RNA, UNTRANSLATED; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84867274607     PISSN: 00029297     EISSN: 15376605     Source Type: Journal    
DOI: 10.1016/j.ajhg.2012.08.017     Document Type: Article

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