Oxygen-induced embryopathy and the significance of glutathione-dependent antioxidant system in the rat embryo during early organogenesis

Free Radical Biology and Medicine

Volumn 22, Issue 3, 1997, Pages 447-454

  Ishibashi, Miwa ^a   Akazawa, Shoichi ^a   Sakamaki, Hiroyuki ^a   Matsumoto, Kazunari ^a   Yamasaki, Hironori ^a   Yamaguchi, Yoshihiko ^a   Goto, Shinji ^b   Urata, Yoshishige ^b   Kondo, Takahito ^b   Nagataki, Shigenobu ^a,b  

^a Second Department of Internal Medicine   (Japan)

^b NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Glutamylcysteine synthetase ( GCS); Embryo culture; Free radicals; Glutathione peroxidase (GPX); Glutathione S transferase (GST); Glutathoine (GSH); Hydrogen peroxide (H2O2); Neural tube defects; Oxidative stress

Indexed keywords

ANTIOXIDANT; BUTHIONINE SULFOXIMINE; FREE RADICAL; GAMMA GLUTAMYLCYCLOTRANSFERASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; HYDROGEN PEROXIDE; MESSENGER RNA; OXYGEN RADICAL;

ANIMAL MODEL; ARTICLE; CONGENITAL MALFORMATION; EMBRYO; EMBRYO CULTURE; EMBRYO DEVELOPMENT; ENZYME ACTIVITY; GENE EXPRESSION; NEURAL TUBE DEFECT; NONHUMAN; ORGANOGENESIS; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIOXIDANTS; CULTURE TECHNIQUES; EMBRYO; EMBRYONIC AND FETAL DEVELOPMENT; FEMALE; FETAL DISEASES; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; HUMANS; MALE; NEURAL TUBE DEFECTS; OXYGEN; RATS; RATS, WISTAR; RNA, MESSENGER;

EID: 0031026171     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(96)00338-3     Document Type: Article

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