Reactive oxygen species-regulated glycogen synthase kinase-3β activation contributes to all-trans retinoic acid-induced apoptosis in granulocyte-differentiated HL60 cells

Biochemical Pharmacology

Volumn 88, Issue 1, 2014, Pages 86-94

  Wang, Chi Yun ^a   Yang, Tsan Tzu ^a   Chen, Chia Ling ^a   Lin, Wei Chieh ^a   Lin, Chiou Feng ^a,b  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

Acute promyelocytic leukemia; All trans retionic acid; Apoptosis; Glycogen synthase kinase 3 ; NADPH oxidase; Reactive oxygen species

Indexed keywords

CASPASE 3; DIMETHYL SULFOXIDE; GLYCOGEN SYNTHASE KINASE 3BETA; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN MCL 1; PROTEIN P47; PROTEIN P67; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RETINOIC ACID;

APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL STRAIN HL 60; GRANULOCYTE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

6-BROMOINDIRUBIN-3′-OXIME (PUBCHEM CID: 5287844); ACUTE PROMYELOCYTIC LEUKEMIA; ALL-TRANS RETIONIC ACID; ALL-TRANS-RETINOIC ACID (PUBCHEM CID: 444795); APOPTOSIS; DIPHENYLENE IODONIUM (PUBCHEM CID: 3101); GLYCOGEN SYNTHASE KINASE-3Β; LITHIUM CHLORIDE (PUBCHEM CID: 433294); LY294002 (PUBCHEM CID: 3974); NADPH OXIDASE; PHORBOL 12-MYRISTATE 13-ACETATE (PUBCHEM CID: 27924); REACTIVE OXYGEN SPECIES; SB415286 (PUBCHEM CID: 4210951);

APOPTOSIS; CELL DIFFERENTIATION; ENZYME ACTIVATION; FLOW CYTOMETRY; GLYCOGEN SYNTHASE KINASE 3; GRANULOCYTES; HL-60 CELLS; HUMANS; REACTIVE OXYGEN SPECIES; TRETINOIN;

EID: 84896707473     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2013.12.021     Document Type: Article

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