Antisense inhibition of Bax mRNA increases survival of terminally differentiated HL60 cells

Antisense and Nucleic Acid Drug Development

Volumn 8, Issue 4, 1998, Pages 341-350

  Manfredini, Rossella ^a   Capobianco, Massimo L ^b   Trevisan, Francesca ^a   Rauzi, Francesca ^b   Barbieri, Daniela ^a   Citro, Gennaro ^c   Tagliafico, Enrico ^a   Ferrari, Sergio ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^b CNR   (Italy)

^c REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; RETINOIC ACID;

APOPTOSIS; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRAIN HL 60; CELL SURVIVAL; CONTROLLED STUDY; DNA DETERMINATION; DRUG DESIGN; FLOW CYTOMETRY; GRANULOCYTE; HUMAN; HUMAN CELL; MOLECULAR GENETICS; PRIORITY JOURNAL; PROTEIN FAMILY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ATRA;

EID: 0031664240     PISSN: 10872906     EISSN: None     Source Type: Journal    
DOI: 10.1089/oli.1.1998.8.341     Document Type: Article

References (8)

1. ABRAHAMS, J.P., VAN DEN BERG, M., VAN BATENBURG, E., and PLEIJ, C. (1990). Prediction of RNA secondary structure, including pseudoknotting, by computer simulation. Nucleic Acids Res. 18, 3035-3044.
2. AGARWAL, N., and MEHTA, K. (1997). Possible involvement of bcl-2 pathway in retinoid X receptor alpha-induced apoptosis of HL60 cells. Biochem. Biophys. Res. Commun. 230, 251-253.
3. APTE, S.S., MATTEI, M.G., and OLSEN, B.R. (1995). Mapping of the human Bax gene to chromosome 19q13.3-q13.4 and isolation of a novel alternatively spliced transcript, Bax delta. Genomics 26, 592-594.
4. DOLBEARE, F., GRATZNER, H., PALLAVICINI, M.G., and GRAY, J.W. (1983). How cytometric measurement of total DNA content and incorporated bromodeoxyuridine. Proc. Natl. Acad. Sci. USA 80, 5573-5577.
5. EVAN, G.I., WYLLIE, A.H., GILBERT, C.S., LITTLEWOOD, T.D., LAND, H., BROOKS, M., WATERS, C.M., PENN, L.Z., and HANCOCK, D.C. (1992). Induction of apoptosis in fibroblast by c-myc protein. Cell 69, 199-128.
6. FERRARI, S., DONNELLI, A., MANFREDINI, R., SARTI, M., RONCAGLIA, R., TAGLIAFICO, E., ROSSI, E., TORELLI, G., and TORELLI, U. (1990). Differential effects of c-myb and c-fes antisense oligodeoxynucleotides on granulocytic differentiation of human myeloid leukemia HL60 cells. Cell Growth Diff. 1, 543-548.
7. 2-microglobulin. Proc. Natl. Acad. Sci. USA 68, 6613-6617.
8. YONISH-ROUACH, E., RESNITZY, D., LOTEM, J., SACHS, L., KIMKI, A., and OREM, M. (1991). Wild-type p53 induces apoptosis of myeloid leukemic cells that is inhibited by interleukin-6. Nature 352, 345-347.