Involvement of autophagy in recombinant human arginase-induced cell apoptosis and growth inhibition of malignant melanoma cells

Applied Microbiology and Biotechnology

Volumn 98, Issue 6, 2014, Pages 2485-2494

  Wang, Ziyu ^a   Shi, Xunlong ^a   Li, Yubin ^a,b   Zeng, Xian ^a   Fan, Jiajun ^a   Sun, Yun ^a   Xian, Zongshu ^a   Zhang, Guoping ^a   Wang, Shaofei ^a   Hu, Haifeng ^c   Ju, Dianwen ^a  

^a FUDAN UNIVERSITY   (China)

^b NANJING AGRICULTURAL UNIVERSITY   (China)

^c SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY   (China)

Author keywords

Apoptosis; Arginase; Autophagy; Growth inhibition; Mitochondria; ROS

Indexed keywords

ARGINASE; AUTOPHAGY; GROWTH INHIBITION; MITOCHONDRIAL MEMBRANE POTENTIAL; MOLECULAR MECHANISM; N-ACETYL L-CYSTEINE; REACTIVE OXYGEN SPECIES; ROS;

ACETYLCYSTEINE; AMINO ACIDS; CELL GROWTH; DERMATOLOGY; GROWTH KINETICS; MITOCHONDRIA; ONCOLOGY;

CELL DEATH;

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; ACETYLCYSTEINE; ARGINASE; CHLOROQUINE; CYCLOSPORIN A; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; REACTIVE OXYGEN METABOLITE; RECOMBINANT ENZYME;

APOPTOSIS; BIOCHEMISTRY; CANCER; CATABOLISM; CYTOLOGY; ENZYME ACTIVITY; GROWTH REGULATOR; HOMINID; INHIBITION; MITOCHONDRION; MOLECULAR ANALYSIS; SKIN DISORDER;

APOPTOSIS; ARTICLE; AUTOPHAGY; CELL GROWTH; CELL VIABILITY ASSAY; CONTROLLED STUDY; GROWTH INHIBITION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MELANOMA; MELANOMA CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; TRANSMISSION ELECTRON MICROSCOPY;

ANTINEOPLASTIC AGENTS; APOPTOSIS; ARGINASE; AUTOPHAGY; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; MELANOCYTES; REACTIVE OXYGEN SPECIES; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION;

EID: 84896698950     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-013-5118-0     Document Type: Article

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