Atorvastatin attenuates neuropathic pain in rat neuropathy model by down-regulating oxidative damage at peripheral, spinal and supraspinal levels

Neurochemistry International

Volumn 68, Issue 1, 2014, Pages 1-9

  Pathak, Nitya N ^a   Balaganur, Venkanna ^a   Lingaraju, Madhu C ^a   Kant, Vinay ^a   Latief, Najeeb ^a   More, Amar S ^a   Kumar, Dhirendra ^a   Kumar, Dinesh ^a   Tandan, Surendra K ^a  

^a INDIAN VETERINARY RESEARCH INSTITUTE   (India)

Author keywords

Atorvastatin; Chronic constriction injury; Hyperalgesia; Neuropathic pain; Oxidative stress

Indexed keywords

ATORVASTATIN; CARBONYL DERIVATIVE; CATALASE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; MALONALDEHYDE; NITRIC OXIDE; PROTEIN CARBONYL; SUPEROXIDE; SUPEROXIDE DISMUTASE; THIOL; UNCLASSIFIED DRUG; ANTIOXIDANT; HEPTANOIC ACID DERIVATIVE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PYRROLE DERIVATIVE;

ADULT; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; HYPERALGESIA; MALE; NEUROPATHIC PAIN; NONHUMAN; OXIDATIVE STRESS; PAIN ASSESSMENT; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT; SCIATIC NERVE; SPINAL CORD; TISSUE LEVEL; TREATMENT OUTCOME; ANIMAL; COMPLICATION; DRUG EFFECTS; NEURALGIA; WISTAR RAT;

ANIMALS; ANTIOXIDANTS; DOWN-REGULATION; HEPTANOIC ACIDS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; HYPERALGESIA; MALE; NEURALGIA; OXIDATIVE STRESS; PYRROLES; RATS, WISTAR; SCIATIC NERVE; SPINAL CORD;

EID: 84896695953     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2014.01.014     Document Type: Article

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