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ChemMedChem

Volumn 9, Issue 3, 2014, Pages 560-565

Toward drug repurposing in epigenetics: Olsalazine as a hypomethylating compound active in a cellular context

(5) Méndez Lucio, Oscar c,d Tran, Jeremy b Medina Franco, José L a Meurice, Nathalie a Muller, Mark b

a MAYO CLINIC (United States)

b UNIVERSITY OF CENTRAL FLORIDA COLLEGE OF MEDICINE (United States)

c UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO (Mexico)

d UNIVERSITY OF CAMBRIDGE (United Kingdom)

Author keywords

cancer; DNA methylation; drug discovery; drug repurposing; hypomethylating agents; similarity searching

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; AZACITIDINE; DNA; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3B; DNA METHYLTRANSFERASE INHIBITOR; DOXYCYCLINE; HYDRALAZINE; NANAOMYCIN A; NSC 14778; OLSALAZINE; PROCAINAMIDE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DNA METHYLATION; DRUG BINDING SITE; DRUG CYTOTOXICITY; DRUG REPOSITIONING; EPIGENETICS; FEMALE; HUMAN; HUMAN CELL; IC 50; PRIORITY JOURNAL;

CANCER; DNA METHYLATION; DRUG DISCOVERY; DRUG REPURPOSING; HYPOMETHYLATING AGENTS; SIMILARITY SEARCHING;

AMINOSALICYLIC ACIDS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DNA; DNA METHYLATION; DRUG REPOSITIONING; EPIGENESIS, GENETIC; HELA CELLS; HUMANS; MOLECULAR STRUCTURE;

EID: 84896691228 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.201300555 Document Type: Article

Times cited : (69)

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