Identification of novel inhibitors of dna methylation by screening of a chemical library

ACS Chemical Biology

Volumn 8, Issue 3, 2013, Pages 543-548

  Ceccaldi, Alexandre ^a,b,c   Rajavelu, Arumugam ^d   Ragozin, Sergey ^d   Sénamaud Beaufort, Catherine ^a,b   Bashtrykov, Pavel ^d   Testa, Noé ^a,b   Dali Ali, Hana ^a,b   Maulay Bailly, Christine ^a   Amand, Séverine ^a   Guianvarc'H, Dominique ^e   Jeltsch, Albert ^d   Arimondo, Paola B ^a,b,f  

^a MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

^b INSERM   (France)

^c SORBONNE UNIVERSITÉ   (France)

^d UNIVERSITY OF STUTTGART   (Germany)

^e CNRS   (France)

^f INSTITUT DE RECHERCHE PIERRE FABRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

2,3 DICHLORO 1,4 NAPHTHOQUINONE; AZACITIDINE; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE INHIBITOR; DNA TOPOISOMERASE; HARMINE; N PHTHALOYLTRYPTOPHAN; NAPHTHOQUINONE; NATURAL PRODUCT; ORGANOCHLORINE DERIVATIVE; PESTICIDE; S ADENOSYLMETHIONINE; SEMPERVIRIN; UNCLASSIFIED DRUG; DNA; DNA (CYTOSINE 5) METHYLTRANSFERASE; ENZYME INHIBITOR; MOLECULAR LIBRARY;

ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BIOCHEMISTRY; BIOLOGICAL ACTIVITY; CELL STRAIN HEK293; CHEMICAL STRUCTURE; CYTOTOXICITY; DNA METHYLATION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; ANALYSIS; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL DEATH; CELL PROLIFERATION; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; HEK293 CELL LINE; METABOLISM; MOLECULAR LIBRARY; PHARMACOLOGY; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL CULTURE;

ANIMALS; CELL DEATH; CELL PROLIFERATION; DNA; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; HEK293 CELLS; HUMANS; MICE; MOLECULAR STRUCTURE; SMALL MOLECULE LIBRARIES; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 84875133093     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb300565z     Document Type: Article

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