Genetic validation of the protein arginine methyltransferase PRMT5 as a candidate therapeutic target in glioblastoma

Cancer Research

Volumn 74, Issue 6, 2014, Pages 1752-1765

  Yan, Fengting ^a   Alinari, Lapo ^a   Lustberg, Mark E ^b   Martin, Ludmila Katherine ^a   Cordero Nieves, Hector M ^c   Banasavadi Siddegowda, Yeshavanth ^c   Virk, Selene ^k   Barnholtz Sloan, Jill ^j   Bell, Erica Hlavin ^h   Wojton, Jeffrey ^h   Jacob, Naduparambil K ^h   Chakravarti, Arnab ^h   Nowicki, Michal O ^c   Wu, Xin ^a   Lapalombella, Rosa ^a   Datta, Jharna ^d   Yu, Bo ^e   Gordon, Kate ^a   Haseley, Amy ^c   Patton, John T ^a   Smith, Porsha L ^a   Ryu, John ^a   Zhang, Xiaoli ^f   Mo, Xiaokui ^f   Marcucci, Guido ^a   Nuovo, Gerard ^g   Kwon, Chang Hyuk ^c   Byrd, John C ^a   Chiocca, E Antonio ^c   Li, Chenglong ⁱ   Sif, Said ^d   Jacob, Samson ^d   Lawler, Sean ^c   Kaur, Balveen ^c   Baiocchi, Robert A ^a   more..

^a Oncology and Bone Marrow Transplantation   (United States)

^b Divisions of Infectious Diseases   (United States)

^c Division of Neurosurgery   (United States)

^d Departments of Molecular and Cellular Biochemistry   (United States)

^e Departments of Chemical Engineering and Biomedical Engineering   (United States)

^f Departments of Statistics   (United States)

^g Departments of Pathology   (United States)

^h Departments of Radiation Oncology   (United States)

ⁱ OHIO STATE UNIVERSITY   (United States)

^j CASE WESTERN RESERVE UNIVERSITY   (United States)

^k CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN ARGININE METHYLTRANSFERASE; PROTEIN ARGININE METHYLTRANSFERASE 5; PROTEIN P53; SMALL INTERFERING RNA; TEMOZOLOMIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER PROGNOSIS; CANCER SURVIVAL; CELL COUNT; CELL CYCLE ARREST; CELL DEATH; CELL GROWTH; CELL MIGRATION; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; GENE; GENE SILENCING; GLIOBLASTOMA; GROWTH INHIBITION; GROWTH RATE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; ST7 GENE; TUMOR GROWTH; TUMOR VOLUME; TUMOR XENOGRAFT;

ANIMALS; APOPTOSIS; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; GLIOBLASTOMA; HUMANS; KAPLAN-MEIER ESTIMATE; MICE; MICE, KNOCKOUT; MICE, NUDE; MOLECULAR TARGETED THERAPY; NEOPLASM TRANSPLANTATION; PROTEIN-ARGININE N-METHYLTRANSFERASES; RNA, SMALL INTERFERING; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 84896515012     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-0884     Document Type: Article

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