Inhibition of the membrane attack complex of the complement system reduces secondary neuroaxonal loss and promotes neurologic recovery after traumatic brain injury in mice

Journal of Immunology

Volumn 192, Issue 5, 2014, Pages 2339-2348

  Fluiter, Kees ^a   Opperhuizen, Anne Loes ^a   Morgan, B Paul ^b   Baas, Frank ^a   Ramaglia, Valeria ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; COMPLEMENT COMPONENT C5 INHIBITOR; COMPLEMENT COMPONENT C6; COMPLEMENT MEMBRANE ATTACK COMPLEX; PLACEBO;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN EDEMA; CELLULAR DISTRIBUTION; COMPLEMENT BLOOD LEVEL; COMPLEMENT INHIBITION; CONTROLLED STUDY; DRUG TARGETING; FEMALE; MACROPHAGE; MALE; MICROGLIA; MOUSE; NERVE CELL LESION; NERVE FIBER DEGENERATION; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; OPSONIZATION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; TRAUMATIC BRAIN INJURY; WEIGHT REDUCTION;

ANIMALS; ARTHROPOD PROTEINS; AXONS; BRAIN INJURIES; CARRIER PROTEINS; COMPLEMENT C5A; COMPLEMENT C5B; COMPLEMENT MEMBRANE ATTACK COMPLEX; FEMALE; MACROPHAGES; MICE; MICE, INBRED BALB C; MICROGLIA; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; RECOVERY OF FUNCTION;

EID: 84896503882     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1302793     Document Type: Article

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