Complement-receptor-3 and scavenger-receptor-AI/II mediated myelin phagocytosis in microglia and macrophages

Neurobiology of Disease

Volumn 12, Issue 1, 2003, Pages 65-72

  Reichert, Fanny ^a   Rotshenker, Shlomo ^a  

^a HEBREW UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; COMPLEMENT COMPONENT C3 RECEPTOR; MONOCLONAL ANTIBODY; MYELIN; SCAVENGER RECEPTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; INHIBITION KINETICS; MACROPHAGE; MICROGLIA; MOUSE; NEWBORN; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN FUNCTION;

EID: 0037327741     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-9961(02)00008-6     Document Type: Article

References (42)

1. Aldskogius H., Kozlova E.N. Central neuron-glial and glial-glial interactions following axon injury. Prog. Neurobiol. 55:1998;1-26.
2. Andrew D., Shock A., Ball E., Ortlepp S., Bell J., Robinson M. KIM185, a monoclonal antibody to CD18 which induces a change in the conformation of CD18 and promotes both LFA-1- and CR3-dependent adhesion. Eur. J. Immunol. 23:1993;2217-2222.
3. Bell M.D., Lopez-Gonzalez R., Lawson L., Hughes D., Fraser I., Gordon S., Perry V.H. Upregulation of the macrophage scavenger receptor in response to different forms of injury in the CNS. J. Neurocytol. 23:1994;605-613.
4. Bruck W., Bruck Y., Diederich U., Piddlesden S.J. The membrane attack complex of complement mediates peripheral nervous system demyelination in vitro. Acta Neuropathol. (Berl.). 90:1995;601-607.
5. Bruck W., Friede R.L. Anti-macrophage CR3 antibody blocks myelin phagocytosis by macrophages in vitro. Acta Neuropathol. (Berl.). 80:1990;415-418.
6. Burudi E.M., Riese S., Stahl P.D., Regnier-Vigouroux A. Identification and functional characterization of the mannose receptor in astrocytes. Glia. 25:1999;44-55.
7. Chen M.S., Huber A.B., van der Haar M.E., Frank M., Schnell L., Spillmann A.A., Christ F., Schwab M.E. Nogo-A is a myelin-associated neurite outgrowth inhibitor and an antigen for monoclonal antibody IN-1. Nature. 403:2000;434-439.
8. Cooper A., Rosen H., Blackwell J.M. Monoclonal antibodies that recognize distinct epitopes of the macrophage type three complement receptor differ in their ability to inhibit binding of Leishmania promastigotes harvested at different phases of their growth cycle. Immunology. 65:1988;511-514.
9. da Costa C.C., van der Laan L.J., Dijkstra C.D., Bruck W. The role of the mouse macrophage scavenger receptor in myelin phagocytosis. Eur. J. Neurosci. 9:1997;2650-2657.
10. DeJong B.A., Smith M.E. A role for complement in phagocytosis of myelin. Neurochem. Res. 22:1997;491-498.
11. Driessens M.H., van Hulten P., Zuurbier A., La Riviere G., Roos E. Inhibition and stimulation of LFA-1 and Mac-1 functions by antibodies against murine CD18. Evidence that the LFA-1 binding sites for ICAM-1, -2, and -3 are distinct. J. Leukocyte Biol. 60:1996;758-765.
12. Fraser I., Hughes D., Gordon S. Divalent cation-independent macrophage adhesion inhibited by monoclonal antibody to murine scavenger receptor. Nature. 364:1993;343-346.
13. Harris E.S., McIntyre T.M., Prescott S.M., Zimmerman G.A. The leukocyte integrins. J. Biol. Chem. 275:2000;23409-23412.
14. Hughes P.E., Pfaff M. Integrin affinity modulation. Trends. Cell Biol. 8:1998;359-364.
15. Humphries M.J. Integrin cell adhesion receptors and the concept of agonism. Trends Pharmacol. Sci. 21:2000;29-32.
16. Humphries M.J. Integrin structure. Biochem. Soc. Trans. 28:2000;311-339.
17. Koski C.L., Vanguri P., Shin M.L. Activation of the alternative pathway of complement by human peripheral nerve myelin. J. Immunol. 134:1985;1810-1814.
18. Liu W.T., Vanguri P., Shin M.L. Studies on demyelination in vitro the requirement of membrane attack components of the complement system . J. Immunol. 41:1983;778-782.
19. McKerracher L., David S., Jackson D.L., Kottis V., Dunn R.J., Braun P.E. Identification of myelin-associated glycoprotein as a major myelin-derived inhibitor of neurite growth. Neuron. 13:1994;805-811.
20. Morell P., Quarles R.H., Norton W.T. Myelin formation, structure, and metabolism. Siegel J.S. Basic Neurochemistry Molecular, Cellular, and Medical Aspects . 1994;117-143 Raven Press, New York.
21. Mosley K., Cuzner M.L. Receptor-mediated phagocytosis of myelin by macrophages and microglia effect of opsonization and receptor blocking agents . Neurochem. Res. 21:1996;481-487.
22. Mukhopadhyay G., Doherty P., Walsh F.S., Crocker P.R., Filbin M.T. A novel role for myelin-associated glycoprotein as an inhibitor of axonal regeneration. Neuron. 13:1994;757-767.
23. Petruzzelli L., Maduzia L., Springer T.A. Activation of lymphocyte function-associated molecule-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) mimicked by an antibody directed against CD18. J. Immunol. 155:1995;854-866.
24. Plow E.F., Haas T.A., Zhang L., Loftus J., Smith J.W. Ligand binding to integrins. J. Biol. Chem. 275:2000;21785-21788.
25. Reichert F., Rotshenker S. Deficient activation of microglia during optic nerve degeneration. J. Neuroimmunol. 70:1996;153-161.
26. Reichert F., Rotshenker S. Galectin-3/MAC-2 in experimental allergic encephalomyelitis. Exp. Neurol. 160:1999;508-514.
27. Reichert F., Slobodov U., Makranz C., Rotshenker S. Modulation (inhibition and augmentation) of complement receptor-3-mediated myelin phagocytosis. Neurobiol. Dis. 8:2001;504-512.
28. Rinner W.A., Bauer J., Schmidts M., Lassmann H., Hickey W.F. Resident microglia and hematogenous macrophages as phagocytes in adoptively transferred experimental autoimmune encephalomyelitis an investigation using rat radiation bone marrow chimeras . Glia. 14:1995;257-266.
29. Robinson M.K., Andrew D., Rosen H., Brown D., Ortlepp S., Stephens P., Butcher E.C. Antibody against the Leu-CAM beta-chain (CD18) promotes both LFA-1- and CR3-dependent adhesion events. J. Immunol. 148:1992;1080-1085.
30. Rosen H., Gordon S. Monoclonal antibody to the murine type 3 complement receptor inhibits adhesion of myelomonocytic cells in vitro and inflammatory cell recruitment in vivo. J. Exp. Med. 166:1987;1685-1701.
31. Sanchez-Madrid F., Simon P., Thompson S., Springer T.A. Mapping of antigenic and functional epitopes on the alpha- and beta- subunits of two related mouse glycoproteins involved in cell interactions, LFA-1 and Mac-1. J. Exp. Med. 158:1983;586-602.
32. Shamash S., Reichert F., Rotshenker S. The cytokine network of Wallerian degeneration tumor necrosis factor-alpha, interleukin-1alpha, and interleukin-1beta . J. Neurosci. 22:2002;3052-3060.
33. Silverman B.A., Carney D.F., Johnston C.A., Vanguri P., Shin M.L. Isolation of membrane attack complex of complement from myelin membranes treated with serum complement. J. Neurochem. 42:1984;1024-1029.
34. Slobodov U., Reichert F., Mirski R., Rotshenker S. Distinct inflammatory stimuli induce different patterns of myelin phagocytosis and degradation in recruited macrophages. Exp. Neurol. 167:2001;401-409.
35. Smith M.E. Phagocytic properties of microglia in vitro implications for a role in multiple sclerosis and EAE . Microsc. Res. Tech. 54:2001;81-94.
36. Stoll G., Jander S. The role of microglia and macrophages in the pathophysiology of the CNS. Prog. Neurobiol. 58:1999;233-247.
37. van der Laan L.J., Ruuls S.R., Weber K.S., Lodder I.J., Dopp E.A., Dijkstra C.D. Macrophage phagocytosis of myelin in vitro determined by flow cytometry phagocytosis is mediated by CR3 and induces production of tumor necrosis factor-alpha and nitric oxide . J. Neuroimmunol. 70:1996;145-152.
38. Vanguri P., Koski C.L., Silverman B., Shin M.L. Complement activation by isolated myelin activation of the classical pathway in the absence of myelin-specific antibodies . Proc. Natl. Acad. Sci. USA. 79:1982;3290-3294.
39. Wilkins J.A., Li A., Ni H., Stupack D.G., Shen C. Control of beta1 integrin function. Localization of stimulatory epitopes. J. Biol. Chem. 271:1996;3046-3051.
40. Williams M.A., Solomkin J.S. Integrin-mediated signaling in human neutrophil functioning. J. Leukocyte Biol. 65:1999;725-736.
41. Xia Y., Vetvicka V., Yan J., Hanikyrova M., Mayadas T., Ross G.D. The beta-glucan-binding lectin site of mouse CR3 (CD11b/CD18) and its function in generating a primed state of the receptor that mediates cytotoxic activation in response to iC3b-opsonized target cells. J. Immunol. 162:1999;2281-2290.
42. Zhang L., Plow E.F. Amino acid sequences within the alpha subunit of integrin alpha M beta 2 (Mac-1) critical for specific recognition of C3bi. Biochemistry. 38:1999;8064-8071.