Construction of a single chain variable fragment antibody (scFv) against tetrodotoxin (TTX) and its interaction with TTX

Toxicon

Volumn 83, Issue , 2014, Pages 22-34

  Wang, Rongzhi ^a   Huang, Ailing ^b   Liu, Licai ^a   Xiang, Shuangshuang ^a   Li, Xiufeng ^a   Ling, Sumei ^a   Wang, Lei ^a   Lu, Tun ^b   Wang, Shihua ^a  

^a FUJIAN AGRICULTURE AND FORESTRY UNIVERSITY   (China)

^b FUZHOU UNIVERSITY   (China)

Author keywords

Computer modeling; Mutation; scFv; Tetrodotoxin (TTX)

Indexed keywords

SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; TETRODOTOXIN; NEUTRALIZING ANTIBODY; PEPTIDE LIBRARY;

ANIMAL EXPERIMENT; ANTIBODY DETECTION; ANTIBODY SCREENING; ANTIBODY STRUCTURE; ANTIGEN BINDING; ANTIGEN SPECIFICITY; ARTICLE; BINDING AFFINITY; BINDING SITE; BIOPANNING; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DNA SEQUENCE; GENE; GENE IDENTIFICATION; IMMUNE RESPONSE; IMMUNOASSAY; MOLECULAR CLONING; MOLECULAR DOCKING; MOLECULAR INTERACTION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHAGE DISPLAY; PREDICTION; PRIORITY JOURNAL; PURIFICATION; RESIDUE ANALYSIS; SEQUENCE ANALYSIS; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY GENE; AMINO ACID SEQUENCE; ANTIBODY AFFINITY; CHEMICAL STRUCTURE; CHEMISTRY; IMMUNOLOGY; MOLECULAR GENETICS; PEPTIDE LIBRARY; POINT MUTATION;

AMINO ACID SEQUENCE; ANTIBODIES, NEUTRALIZING; ANTIBODY AFFINITY; BASE SEQUENCE; BINDING SITES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; POINT MUTATION; SEQUENCE ANALYSIS, PROTEIN; SINGLE-CHAIN ANTIBODIES; TETRODOTOXIN;

EID: 84896469818     PISSN: 00410101     EISSN: 18793150     Source Type: Journal    
DOI: 10.1016/j.toxicon.2014.02.021     Document Type: Article

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