Structure and dynamics of the anti-AMCV scFv(F8): Effects of selected mutations on the antigen combining site

Journal of Structural Biology

Volumn 164, Issue 1, 2008, Pages 119-133

  Arcangeli, Caterina ^a   Cantale, Cristina ^a   Galeffi, Patrizia ^a   Rosato, Vittorio ^a,b  

^a ENEA   (Italy)

^b ENEA C R CASACCIA   (Italy)

Author keywords

Essential dynamics analysis; Molecular dynamics simulation; Single chain fragment; Solvent role; Structure function relationship

Indexed keywords

SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

ANTIBODY COMBINING SITE; ANTIGEN BINDING; ANTIGEN SPECIFICITY; ANTIGEN STRUCTURE; ARTICLE; IN VITRO STUDY; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; MOLECULAR STABILITY; MUTAGENICITY; PRIORITY JOURNAL; PROTEIN CONFORMATION; STRUCTURAL HOMOLOGY; SUBSTITUTION REACTION; WILD TYPE;

BINDING SITES, ANTIBODY; COMPUTER SIMULATION; IMMUNOGLOBULIN VARIABLE REGION; MODELS, MOLECULAR; PLANT VIRUSES; PROTEIN CONFORMATION; PROTEIN ENGINEERING; PROTEIN STABILITY;

ARTICHOKE MOTTLED CRINKLE VIRUS;

EID: 51749110001     PISSN: 10478477     EISSN: 10958657     Source Type: Journal    
DOI: 10.1016/j.jsb.2008.06.013     Document Type: Article

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