Effect of isoflurane on myocardial energetic and oxidative stress in cardiac muscle from Zucker diabetic fatty rat

Journal of Pharmacology and Experimental Therapeutics

Volumn 349, Issue 4, 2014, Pages 21-28

  Shen, Xiaoxu ^a   Bhatt, Niraj ^b   Xu, Jianhong ^c   Meng, Tao ^b   Aon, Miguel A ^b   O'Rourke, Brian ^b   Berkowitz, Dan E ^b   Cortassa, Sonia ^b   Gao, Wei Dong ^b  

^a Dongzhimen Hospital of Beijing University of Chinese Medicine   (China)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANESTHETICS, INHALATION; ANIMALS; CALCIUM; DIABETES MELLITUS, EXPERIMENTAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENERGY METABOLISM; ISOFLURANE; MYOCARDIUM; OBESITY; OXIDATIVE STRESS; OXYGEN CONSUMPTION; RATS; RATS, ZUCKER;

EID: 84896450159     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.113.211144     Document Type: Article

References (45)

1. Axelrod DA, Upchurch GR, Jr, DeMonner S, Stanley JC, Khuri S, Daley J, Henderson WG, and Hayward R (2002) Perioperative cardiovascular risk stratification of patients with diabetes who undergo elective major vascular surgery. J Vasc Surg 35:894-901.
2. Belke DD, Swanson EA, and Dillmann WH (2004) Decreased sarcoplasmic reticulum activity and contractility in diabetic db/db mouse heart. Diabetes 53:3201-3208.
3. Bhatt N, Aon MA, Shen X, O'Rourke B, Gao WD, and Cortassa S (2012) Bioenergetics of contractile function in heart trabeculae from diabetic rats (abstract). Biophys J 102:571a.
4. 2 cost of basal metabolism and excitation-contraction coupling in hearts from type 2 diabetic mice. Am J Physiol Heart Circ Physiol 296:H1373-H1379.
5. Booth GL, Kapral MK, Fung K, and Tu JV (2006) Relation between age and cardiovascular disease in men and women with diabetes compared with non-diabetic people: a population-based retrospective cohort study. Lancet 368:29-36.
6. Boudina S, Sena S, Theobald H, Sheng X, Wright JJ, Hu XX, Aziz S, Johnson JI, Bugger H, and Zaha VG, et al. (2007) Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins. Diabetes 56:2457-2466.
7. Bugger H and Abel ED (2010) Mitochondria in the diabetic heart. Cardiovasc Res 88: 229-240.
8. Cortassa S, Aon MA, O'Rourke B, Jacques R, Tseng HJ, Marbán E, and Winslow RL (2006) A computational model integrating electrophysiology, contraction, and mitochondrial bioenergetics in the ventricular myocyte. Biophys J 91:1564-1589.
9. Cortassa S, O'Rourke B, Winslow RL, and Aon MA (2009) Control and regulation of mitochondrial energetics in an integrated model of cardiomyocyte function. Biophys J 96:2466-2478.
10. Dai S and McNeill JH (1992) Myocardial performance of STZ-diabetic DOCAhypertensive rats. Am J Physiol 263:H1798-H1805.
11. Dai T, Tian Y, Tocchetti CG, Katori T, Murphy AM, Kass DA, Paolocci N, and Gao WD (2007) Nitroxyl increases force development in rat cardiac muscle. J Physiol 580:951-960.
12. David JS, Tavernier B, Amour J, Vivien B, Coriat P, and Riou B (2004) Myocardial effects of halothane and sevoflurane in diabetic rats. Anesthesiology 100:1179-1187.
13. 2+. J Pharmacol Exp Ther 339: 825-831.
14. Dong F, Zhang X, Yang X, Esberg LB, Yang H, Zhang Z, Culver B, and Ren J (2006) Impaired cardiac contractile function in ventricular myocytes from leptin-deficient ob/ob obese mice. J Endocrinol 188:25-36.
15. Flarsheim CE, Grupp IL, and Matlib MA (1996) Mitochondrial dysfunction accompanies diastolic dysfunction in diabetic rat heart. Am J Physiol 271:H192-H202.
16. Ganesh SP, Pietrobon R, Cecílio WA, Pan D, Lightdale N, and Nunley JA (2005) The impact of diabetes on patient outcomes after ankle fracture. J Bone Joint Surg Am 87:1712-1718.
17. Gao WD, Backx PH, Azan-Backx M, and Marban E (1994) Myofilament Ca2+ sensitivity in intact versus skinned rat ventricular muscle. Circ Res 74:408-415.
18. Gao WD, Murray CI, Tian Y, Zhong X, DuMond JF, Shen X, Stanley BA, Foster DB, Wink DA, and King SB, et al. (2012) Nitroxyl-mediated disulfide bond formation between cardiac myofilament cysteines enhances contractile function. Circ Res 111:1002-1011.
19. Golfman LS, Wilson CR, Sharma S, Burgmaier M, Young ME, Guthrie PH, Van Arsdall M, Adrogue JV, Brown KK, and Taegtmeyer H (2005) Activation of PPARgamma enhances myocardial glucose oxidation and improves contractile function in isolated working hearts of ZDF rats. Am J Physiol Endocrinol Metab 289:E328-E336.
20. Halm EA, Tuhrim S, Wang JJ, Rockman C, Riles TS, and Chassin MR (2009) Risk factors for perioperative death and stroke after carotid endarterectomy: results of the New York carotid artery surgery study. Stroke 40:221-229.
21. Hanley PJ, ter Keurs HE, and Cannell MB (2004) Excitation-contraction coupling in the heart and the negative inotropic action of volatile anesthetics. Anesthesiology 101:999-1014.
22. Hattori Y, Azuma M, Gotoh Y, and Kanno M (1987) Negative inotropic effects of halothane, enflurane, and isoflurane in papillary muscles from diabetic rats. Anesth Analg 66:23-28.
23. Heather LC and Clarke K (2011) Metabolism, hypoxia and the diabetic heart. J Mol Cell Cardiol 50:598-605.
24. Hirata N, Shim YH, Pravdic D, Lohr NL, Pratt PF, Jr, Weihrauch D, Kersten JR, Warltier DC, Bosnjak ZJ, and Bienengraeber M (2011) Isoflurane differentially modulates mitochondrial reactive oxygen species production via forward versus reverse electron transport flow: implications for preconditioning. Anesthesiology 115:531-540.
25. Hoeks S, Flu WJ, van Kuijk JP, Bax J, and Poldermans D (2009) Cardiovascular risk assessment of the diabetic patient undergoing major noncardiac surgery. Best Pract Res Clin Endocrinol Metab 23:361-373.
26. Juul AB, Wetterslev J, and Kofoed-Enevoldsen A (2004) Long-term postoperative mortality in diabetic patients undergoing major non-cardiac surgery. Eur J Anaesthesiol 21:523-529.
27. Jweied EE, McKinney RD, Walker LA, Brodsky I, Geha AS, Massad MG, Buttrick PM, and de Tombe PP (2005) Depressed cardiac myofilament function in human diabetes mellitus. Am J Physiol Heart Circ Physiol 289:H2478-H2483.
28. Kersten JR, Schmeling TJ, Pagel PS, Gross GJ, and Warltier DC (1997) Isoflurane mimics ischemic preconditioning via activation of K(ATP) channels: reduction of myocardial infarct size with an acute memory phase. Anesthesiology 87:361-370.
29. Lee TH, Marcantonio ER, Mangione CM, Thomas EJ, Polanczyk CA, Cook EF, Sugarbaker DJ, Donaldson MC, Poss R, and Ho KK, et al. (1999) Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation 100:1043-1049.
30. Ljubkovic M, Mio Y, Marinovic J, Stadnicka A, Warltier DC, Bosnjak ZJ, and Bienengraeber M (2007) Isoflurane preconditioning uncouples mitochondria and protects against hypoxia-reoxygenation. Am J Physiol Cell Physiol 292: C1583-C1590.
31. Okayama H, Hamada M, and Hiwada K (1994) Contractile dysfunction in the diabetic-rat heart is an intrinsic abnormality of the cardiac myocyte. Clin Sci 86: 257-262.
32. Pagel PS, Lowe D, Hettrick DA, Jamali IN, Kersten JR, Tessmer JP, and Warltier DC (1996) Isoflurane, but not halothane, improves indices of diastolic performance in dogs with rapid ventricular, pacing-induced cardiomyopathy. Anesthesiology 85: 644-654.
33. i transient decrease in cardiomyopathy of db/db type 2 diabetic mice. Diabetes 55:608-615.
34. Preckel B, Müllenheim J, Hoff J, Obal D, Heiderhoff M, Thämer V, and Schlack W (2004) Haemodynamic changes during halothane, sevoflurane and desflurane anaesthesia in dogs before and after the induction of severe heart failure. Eur J Anaesthesiol 21:797-806.
35. Ramirez-Correa GA, Jin W, Wang Z, Zhong X, Gao WD, Dias WB, Vecoli C, Hart GW, and Murphy AM (2008) O-Linked GlcNAc modification of cardiac myofilament proteins: a novel regulator of myocardial contractile function. Circ Res 103: 1354-1358.
36. Rithalia A, Qureshi MA, Howarth FC, and Harrison SM (2004) Effects of halothane on contraction and intracellular calcium in ventricular myocytes from streptozotocin-induced diabetic rats. Br J Anaesth 92:246-253.
37. Rusy BF and Komai H (1987) Anesthetic depression of myocardial contractility: a review of possible mechanisms. Anesthesiology 67:745-766.
38. Sag CM, Wagner S, and Maier LS (2013) Role of oxidants on calcium and sodium movement in healthy and diseased cardiac myocytes. Free Radic Biol Med 63: 338-349.
39. Song D, Kuo KH, Yao R, Hutchings SR, and Pang CC (2008) Inducible nitric oxide synthase depresses cardiac contractile function in Zucker diabetic fatty rats. Eur J Pharmacol 579:253-259.
40. Thourani VH, Weintraub WS, Stein B, Gebhart SS, Craver JM, Jones EL, and Guyton RA (1999) Influence of diabetes mellitus on early and late outcome after coronary artery bypass grafting. Ann Thorac Surg 67:1045-1052.
41. Tocchetti CG, Caceres V, Stanley BA, Xie C, Shi S, Watson WH, O'Rourke B, Spadari-Bratfisch RC, Cortassa S, and Akar FG, et al. (2012) GSH or palmitate preserves mitochondrial energetic/redox balance, preventing mechanical dysfunction in metabolically challenged myocytes/hearts from type 2 diabetic mice. Diabetes 61: 3094-3105.
42. van den Brom CE, Huisman MC, Vlasblom R, Boontje NM, Duijst S, Lubberink M, Molthoff CF, Lammertsma AA, van der Velden J, and Boer C, et al. (2009) Altered myocardial substrate metabolism is associated with myocardial dysfunction in early diabetic cardiomyopathy in rats: studies using positron emission tomography. Cardiovasc Diabetol 8:39.
43. Vivien B, Hanouz JL, Gueugniaud PY, Lecarpentier Y, Coriat P, and Riou B (1997) Myocardial effects of halothane and isoflurane in hamsters with hypertrophic cardiomyopathy. Anesthesiology 87:1406-1416.
44. Wilcox CS and Pearlman A (2008) Chemistry and antihypertensive effects of tempol and other nitroxides. Pharmacol Rev 60:418-469.
45. Zhou YT, Grayburn P, Karim A, Shimabukuro M, Higa M, Baetens D, Orci L, and Unger RH (2000) Lipotoxic heart disease in obese rats: implications for human obesity. Proc Natl Acad Sci USA 97:1784-1789.