Reversal of isoflurane-induced depression of myocardial contraction by nitroxyl via myofilament sensitization to Ca 2+

Journal of Pharmacology and Experimental Therapeutics

Volumn 339, Issue 3, 2011, Pages 825-831

  Ding, Wengang ^a   Li, Zhitao ^a   Shen, Xiaoxu ^b   Martin, Jackie ^e   King, S Bruce ^c   Sivakumaran, Vidhya ^e   Paolocci, Nazareno ^d,e   Gao, Wei Dong ^e  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b BEIJING UNIVERSITY OF CHINESE MEDICINE   (China)

^c WAKE FOREST UNIVERSITY   (United States)

^d UNIVERSITY OF PERUGIA   (Italy)

^e JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 NITROSOCYCLOHEXYLACETATE; CALCIUM ION; ISOFLURANE; NITRIC OXIDE DONOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; HEART CONTRACTION; HEART FAILURE; HEART MUSCLE CONTRACTILE FORCE; HEART RIGHT VENTRICLE; HEART STIMULATION; INOTROPISM; MYOFILAMENT; NONHUMAN; PRIORITY JOURNAL; RAT; SENSITIZATION; STEADY STATE;

ACETATES; ANESTHETICS, INHALATION; ANIMALS; CALCIUM; CARDIOTONIC AGENTS; DRUG EVALUATION, PRECLINICAL; FREE RADICALS; GLUCOSE; HEART VENTRICLES; ISOFLURANE; MYOCARDIAL CONTRACTION; MYOFIBRILS; NITROGEN OXIDES; NITROSO COMPOUNDS; RATS; RYANODINE; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; TROMETHAMINE; VENTRICULAR FUNCTION;

EID: 81555207897     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.111.185272     Document Type: Article

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