GSH or palmitate preserves mitochondrial energetic/redox balance, preventing mechanical dysfunction in metabolically challenged myocytes/hearts from type 2 diabetic mice

Diabetes

Volumn 61, Issue 12, 2012, Pages 3094-3105

  Tocchetti, Carlo G ^a   Caceres, Viviane ^a   Stanley, Brian A ^a   Xie, Chaoqin ^b   Shi, Sa ^a   Watson, Walter H ^c   O'Rourke, Brian ^a   Spadari Bratfisch, Regina C ^a   Cortassa, Sonia ^a   Akar, Fadi G ^b   Paolocci, Nazareno ^a,d   Aon, Miguel A ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c University of Louisville School of Medicine   (United States)

^d UNIVERSITY OF PERUGIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME C OXIDASE; GLUCOSE; GLUTATHIONE; ISOPRENALINE; PALMITIC ACID; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); THIOREDOXIN 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; EXERCISE; GLYCEMIC CONTROL; HEART DISEASE; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE CELL; HEART WORK; MALE; METABOLIC STRESS; MITOCHONDRIAL RESPIRATION; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; REDOX STRESS;

ANIMALS; DIABETES MELLITUS, TYPE 2; GLUCOSE; GLUTATHIONE; ISOPROTERENOL; MICE; MITOCHONDRIA; MODELS, BIOLOGICAL; MUSCLE CELLS; OXIDATION-REDUCTION; PALMITATES; REACTIVE OXYGEN SPECIES;

EID: 84870345149     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db12-0072     Document Type: Article

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