-
1
-
-
0017670013
-
Structural gene identification and mapping by DNA-mRNA hybridarrested cell-free translation
-
PMID:270678
-
Paterson BM, Roberts BE, Kuff EL. Structural gene identification and mapping by DNA-mRNA hybridarrested cell-free translation. Proc Natl Acad Sci U S A 1977; 74:4370-4. PMID:270678; http://dx.doi.org/10.1073/pnas.74.10.4370.
-
(1977)
Proc Natl Acad Sci U S A
, vol.74
, pp. 4370-4374
-
-
Paterson, B.M.1
Roberts, B.E.2
Kuff, E.L.3
-
2
-
-
0032766821
-
Peptide nucleic acid. A molecule with two identities
-
Nielsen PE. Peptide nucleic acid. A molecule with two identities. Acc Chem Res 1999; 32:624-30; http://dx.doi.org/10.1021/ar980010t
-
(1999)
Acc Chem Res
, vol.32
, pp. 624-630
-
-
Nielsen, P.E.1
-
3
-
-
0032998423
-
Keeping the biotechnology of antisense in context
-
PMID:10096271
-
Stein CA. Keeping the biotechnology of antisense in context. Nat Biotechnol 1999; 17:209. PMID:10096271; http://dx.doi.org/10.1038/6909.
-
(1999)
Nat Biotechnol
, vol.17
, pp. 209
-
-
Stein, C.A.1
-
4
-
-
0033947612
-
Aspects of the transport and delivery of antisense oligonucleotides
-
PMID:11249624
-
Juliano RL, Yoo H. Aspects of the transport and delivery of antisense oligonucleotides. Curr Opin Mol Ther 2000; 2:297-303. PMID:11249624.
-
(2000)
Curr Opin Mol Ther
, vol.2
, pp. 297-303
-
-
Juliano, R.L.1
Yoo, H.2
-
5
-
-
11244337800
-
Antisense phosphorodiamidate morpholino oligomer length and target position effects on gene-specific inhibition in Escherichia coli
-
PMID:15616302
-
Deere J, Iversen P, Geller BL. Antisense phosphorodiamidate morpholino oligomer length and target position effects on gene-specific inhibition in Escherichia coli. Antimicrob Agents Chemother 2005; 49:249-55. PMID:15616302; http://dx.doi.org/10.1128/AAC.49.1.249-255.2005.
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 249-255
-
-
Deere, J.1
Iversen, P.2
Geller, B.L.3
-
6
-
-
0030969949
-
Morpholino and phosphorothioate antisense oligomers compared in cell-free and in-cell systems
-
PMID:9149841
-
Summerton J, Stein D, Huang SB, Matthews P, Weller D, Partridge M. Morpholino and phosphorothioate antisense oligomers compared in cell-free and in-cell systems. Antisense Nucleic Acid Drug Dev 1997; 7:63-70. PMID:9149841; http://dx.doi.org/10.1089/oli.1.1997.7.63.
-
(1997)
Antisense Nucleic Acid Drug Dev
, vol.7
, pp. 63-70
-
-
Summerton, J.1
Stein, D.2
Huang, S.B.3
Matthews, P.4
Weller, D.5
Partridge, M.6
-
7
-
-
0032473890
-
LNA (Locked Nucleic Acids): Synthesis of the adenine, cytosine, guanine, 5-methylcytosine, thymine and uracil bicyclonucleoside monomers, oligomerisation, and unprecedented nucleic acid recognition
-
Koshkin AA, Singh SK, Nielsen P, Rajwanshi VK, Kumar R, Meldgaard M, et al. LNA (Locked Nucleic Acids): Synthesis of the adenine, cytosine, guanine, 5-methylcytosine, thymine and uracil bicyclonucleoside monomers, oligomerisation, and unprecedented nucleic acid recognition. Tetrahedron 1998; 54:3607-30; http://dx.doi.org/10.1016/S0040-4020(98)00094-5.
-
(1998)
Tetrahedron
, vol.54
, pp. 3607-3630
-
-
Koshkin, A.A.1
Singh, S.K.2
Nielsen, P.3
Rajwanshi, V.K.4
Kumar, R.5
Meldgaard, M.6
-
8
-
-
0026341239
-
Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide
-
PMID:1962210
-
Nielsen PE, Egholm M, Berg RH, Buchardt O. Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide. Science 1991; 254:1497-500. PMID:1962210; http://dx.doi.org/10.1126/science.1962210.
-
(1991)
Science
, vol.254
, pp. 1497-1500
-
-
Nielsen, P.E.1
Egholm, M.2
Berg, R.H.3
Buchardt, O.4
-
9
-
-
0037143705
-
Profiling protein function with small molecule microarrays
-
PMID:12167675
-
Winssinger N, Ficarro S, Schultz PG, Harris JL. Profiling protein function with small molecule microarrays. Proc Natl Acad Sci U S A 2002; 99:11139-44. PMID:12167675; http://dx.doi.org/10.1073/pnas.172286899.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 11139-11144
-
-
Winssinger, N.1
Ficarro, S.2
Schultz, P.G.3
Harris, J.L.4
-
10
-
-
34249296349
-
Expanding the scope of PNA-encoded libraries: Divergent synthesis of libraries targeting cysteine, serine and metalloproteases as well as tyrosine phosphatases
-
Debaene F, Da Silva JA, Pianowski Z, Duran FJ, Winssinger N. Expanding the scope of PNA-encoded libraries: divergent synthesis of libraries targeting cysteine, serine and metalloproteases as well as tyrosine phosphatases. Tetrahedron 2007; 63:6577-86; http://dx.doi.org/10.1016/j.tet.2007.03.033.
-
(2007)
Tetrahedron
, vol.63
, pp. 6577-6586
-
-
Debaene, F.1
da Silva, J.A.2
Pianowski, Z.3
Duran, F.J.4
Winssinger, N.5
-
11
-
-
84990238662
-
Peptide Nucleic-Acids (Pna) -Oligonucleotide Analogs with an Achiral Peptide Backbone
-
Egholm M, Buchardt O, Nielsen PE, Berg RH. Peptide Nucleic-Acids (Pna) -Oligonucleotide Analogs with an Achiral Peptide Backbone. J Am Chem Soc 1992; 114:1895-7; http://dx.doi.org/10.1021/ja00031a062.
-
(1992)
J Am Chem Soc
, vol.114
, pp. 1895-1897
-
-
Egholm, M.1
Buchardt, O.2
Nielsen, P.E.3
Berg, R.H.4
-
12
-
-
33744521396
-
Synthesis of two new thymine-containing negatively charged PNA monomers
-
Boyarskaya NP, Kirillova YG, Stotland EA, Prokhorov DI, Zvonkova EN, Shvets VI. Synthesis of two new thymine-containing negatively charged PNA monomers. Dokl Chem 2006; 408:57-60; http://dx.doi.org/10.1134/S0012500806050016.
-
(2006)
Dokl Chem
, vol.408
, pp. 57-60
-
-
Boyarskaya, N.P.1
Kirillova, Y.G.2
Stotland, E.A.3
Prokhorov, D.I.4
Zvonkova, E.N.5
Shvets, V.I.6
-
13
-
-
34250305133
-
Hydrophilic modifications in peptide nucleic acid -Synthesis and properties of PNA possessing 5-hydroxymethyluracil and 5-hydroxymethylcytosine
-
Hudson RHE, Liu YH, Wojciechowski F. Hydrophilic modifications in peptide nucleic acid -Synthesis and properties of PNA possessing 5-hydroxymethyluracil and 5-hydroxymethylcytosine. Can J Chem 2007; 85:302-12; http://dx.doi.org/10.1139/v07-030.
-
(2007)
Can J Chem
, vol.85
, pp. 302-312
-
-
Hudson, R.H.E.1
Liu, Y.H.2
Wojciechowski, F.3
-
14
-
-
36949011002
-
PNA conjugated to high-molecular weight poly(ethylene glycol): Synthesis and properties
-
PMID:18066875
-
Bonora GM, Drioli S, Ballico M, Faccini A, Corradini R, Cogoi S, et al. PNA conjugated to high-molecular weight poly(ethylene glycol): synthesis and properties. Nucleosides Nucleotides Nucleic Acids 2007; 26:661-4. PMID:18066875; http://dx.doi.org/10.1080/15257770701490548.
-
(2007)
Nucleosides Nucleotides Nucleic Acids
, vol.26
, pp. 661-664
-
-
Bonora, G.M.1
Drioli, S.2
Ballico, M.3
Faccini, A.4
Corradini, R.5
Cogoi, S.6
-
15
-
-
33746904737
-
A simple gammabackbone modification preorganizes peptide nucleic acid into a helical structure
-
PMID:16881656
-
Dragulescu-Andrasi A, Rapireddy S, Frezza BM, Gayathri C, Gil RR, Ly DH. A simple gammabackbone modification preorganizes peptide nucleic acid into a helical structure. J Am Chem Soc 2006; 128:10258-67. PMID:16881656; http://dx.doi.org/10.1021/ja0625576.
-
(2006)
J Am Chem Soc
, vol.128
, pp. 10258-10267
-
-
Dragulescu-Andrasi, A.1
Rapireddy, S.2
Frezza, B.M.3
Gayathri, C.4
Gil, R.R.5
Ly, D.H.6
-
16
-
-
37849040469
-
Strand invasion of mixed-sequence B-DNA by acridine-linked, gamma-peptide nucleic acid (gamma-PNA)
-
PMID:18027941
-
Rapireddy S, He G, Roy S, Armitage BA, Ly DH. Strand invasion of mixed-sequence B-DNA by acridine-linked, gamma-peptide nucleic acid (gamma-PNA). J Am Chem Soc 2007; 129:15596-600. PMID:18027941; http://dx.doi.org/10.1021/ja074886j
-
(2007)
J Am Chem Soc
, vol.129
, pp. 15596-15600
-
-
Rapireddy, S.1
He, G.2
Roy, S.3
Armitage, B.A.4
Ly, D.H.5
-
17
-
-
79960155483
-
Synthesis and characterization of conformationally preorganized, (R)-diethylene glycol-containing γ-peptide nucleic acids with superior hybridization properties and water solubility
-
PMID:21619025
-
Sahu B, Sacui I, Rapireddy S, Zanotti KJ, Bahal R, Armitage BA, et al. Synthesis and characterization of conformationally preorganized, (R)-diethylene glycol-containing γ-peptide nucleic acids with superior hybridization properties and water solubility. J Org Chem 2011; 76:5614-27. PMID:21619025; http://dx.doi.org/10.1021/jo200482d
-
(2011)
J Org Chem
, vol.76
, pp. 5614-5627
-
-
Sahu, B.1
Sacui, I.2
Rapireddy, S.3
Zanotti, K.J.4
Bahal, R.5
Armitage, B.A.6
-
18
-
-
79955861755
-
Strand invasion of mixed-sequence, double-helical B-DNA by γ-peptide nucleic acids containing G-clamp nucleobases under physiological conditions
-
PMID:21476606
-
Rapireddy S, Bahal R, Ly DH. Strand invasion of mixed-sequence, double-helical B-DNA by γ-peptide nucleic acids containing G-clamp nucleobases under physiological conditions. Biochemistry 2011; 50:3913-8. PMID:21476606; http://dx.doi.org/10.1021/bi2002554.
-
(2011)
Biochemistry
, vol.50
, pp. 3913-3918
-
-
Rapireddy, S.1
Bahal, R.2
Ly, D.H.3
-
19
-
-
69349104918
-
Strand invasion of extended, mixed-sequence B-DNA by gammaPNAs
-
PMID:19663424
-
He G, Rapireddy S, Bahal R, Sahu B, Ly DH. Strand invasion of extended, mixed-sequence B-DNA by gammaPNAs. J Am Chem Soc 2009; 131:12088-90. PMID:19663424; http://dx.doi.org/10.1021/ja900228j
-
(2009)
J Am Chem Soc
, vol.131
, pp. 12088-12090
-
-
He, G.1
Rapireddy, S.2
Bahal, R.3
Sahu, B.4
Ly, D.H.5
-
20
-
-
84869053315
-
Effect of steric constraint at the γ-backbone position on the conformations and hybridization properties of PNAs
-
Crawford MJ, Rapireddy S, Bahal R, Sacui I, Ly DH. Effect of steric constraint at the γ-backbone position on the conformations and hybridization properties of PNAs. J Nucleic Acids 2011:652702, 10 pp.
-
(2011)
J Nucleic Acids
, pp. 10
-
-
Crawford, M.J.1
Rapireddy, S.2
Bahal, R.3
Sacui, I.4
Ly, D.H.5
-
21
-
-
84155184286
-
Sequence-unrestricted, Watson-Crick recognition of double helical B-DNA by (R)-miniPEG-γPNAs
-
PMID:22135012
-
Bahal R, Sahu B, Rapireddy S, Lee CM, Ly DH. Sequence-unrestricted, Watson-Crick recognition of double helical B-DNA by (R)-miniPEG-γPNAs. Chembiochem 2012; 13:56-60. PMID:22135012; http://dx.doi.org/10.1002/cbic.201100646.
-
(2012)
Chembiochem
, vol.13
, pp. 56-60
-
-
Bahal, R.1
Sahu, B.2
Rapireddy, S.3
Lee, C.M.4
Ly, D.H.5
-
22
-
-
78650919363
-
Nanoparticles deliver triplex-forming PNAs for site-specific genomic recombination in CD34+ human hematopoietic progenitors
-
PMID:20859257
-
McNeer NA, Chin JY, Schleifman EB, Fields RJ, Glazer PM, Saltzman WM. Nanoparticles deliver triplex-forming PNAs for site-specific genomic recombination in CD34+ human hematopoietic progenitors. Mol Ther 2011; 19:172-80. PMID:20859257; http://dx.doi.org/10.1038/mt.2010.200.
-
(2011)
Mol Ther
, vol.19
, pp. 172-180
-
-
McNeer, N.A.1
Chin, J.Y.2
Schleifman, E.B.3
Fields, R.J.4
Glazer, P.M.5
Saltzman, W.M.6
-
23
-
-
84882283204
-
Systemic delivery of triplex-forming PNA and donor DNA by nanoparticles mediates site-specific genome editing of human hematopoietic cells in vivo
-
PMID:23076379
-
McNeer NA, Schleifman EB, Cuthbert A, Brehm M, Jackson A, Cheng C, et al. Systemic delivery of triplex-forming PNA and donor DNA by nanoparticles mediates site-specific genome editing of human hematopoietic cells in vivo. Gene Ther 2012; 20:658-69. PMID:23076379.
-
(2012)
Gene Ther
, vol.20
, pp. 658-669
-
-
McNeer, N.A.1
Schleifman, E.B.2
Cuthbert, A.3
Brehm, M.4
Jackson, A.5
Cheng, C.6
-
24
-
-
84860720576
-
Polymer nanoparticle-mediated delivery of microRNA inhibition and alternative splicing
-
PMID:22482958
-
Cheng CJ, Saltzman WM. Polymer nanoparticle-mediated delivery of microRNA inhibition and alternative splicing. Mol Pharm 2012; 9:1481-8. PMID:22482958.
-
(2012)
Mol Pharm
, vol.9
, pp. 1481-1488
-
-
Cheng, C.J.1
Saltzman, W.M.2
-
25
-
-
16044373004
-
Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene
-
PMID:8751444
-
Samson M, Libert F, Doranz BJ, Rucker J, Liesnard C, Farber CM, et al. Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature 1996; 382:722-5. PMID:8751444; http://dx.doi.org/10.1038/382722a0.
-
(1996)
Nature
, vol.382
, pp. 722-725
-
-
Samson, M.1
Libert, F.2
Doranz, B.J.3
Rucker, J.4
Liesnard, C.5
Farber, C.M.6
-
26
-
-
80053145141
-
Targeted disruption of the CCR5 gene in human hematopoietic stem cells stimulated by peptide nucleic acids
-
PMID:21944757
-
Schleifman EB, Bindra R, Leif J, del Campo J, Rogers FA, Uchil P, et al. Targeted disruption of the CCR5 gene in human hematopoietic stem cells stimulated by peptide nucleic acids. Chem Biol 2011; 18:1189-98. PMID:21944757; http://dx.doi.org/10.1016/j.chembiol.2011.07.010.
-
(2011)
Chem Biol
, vol.18
, pp. 1189-1198
-
-
Schleifman, E.B.1
Bindra, R.2
Leif, J.3
del Campo, J.4
Rogers, F.A.5
Uchil, P.6
-
27
-
-
0029295025
-
Solid-phase synthesis of peptide nucleic acids
-
PMID:9222994
-
Christensen L, Fitzpatrick R, Gildea B, Petersen KH, Hansen HF, Koch T, et al. Solid-phase synthesis of peptide nucleic acids. J Pept Sci 1995; 1:175-83. PMID:9222994; http://dx.doi.org/10.1002/psc.310010304.
-
(1995)
J Pept Sci
, vol.1
, pp. 175-183
-
-
Christensen, L.1
Fitzpatrick, R.2
Gildea, B.3
Petersen, K.H.4
Hansen, H.F.5
Koch, T.6
-
28
-
-
64349120434
-
Synthesis of conformationally preorganized and cell-permeable guanidine-based gammapeptide nucleic acids (gammaGPNAs)
-
PMID:19161276
-
Sahu B, Chenna V, Lathrop KL, Thomas SM, Zon G, Livak KJ, et al. Synthesis of conformationally preorganized and cell-permeable guanidine-based gammapeptide nucleic acids (gammaGPNAs). J Org Chem 2009; 74:1509-16. PMID:19161276; http://dx.doi.org/10.1021/jo802211n
-
(2009)
J Org Chem
, vol.74
, pp. 1509-1516
-
-
Sahu, B.1
Chenna, V.2
Lathrop, K.L.3
Thomas, S.M.4
Zon, G.5
Livak, K.J.6
-
29
-
-
33746822930
-
Synthesis of cellpermeable peptide nucleic acids and characterization of their hybridization and uptake properties
-
PMID:16809033
-
Zhou P, Dragulescu-Andrasi A, Bhattacharya B, O'Keefe H, Vatta P, Hyldig-Nielsen JJ, et al. Synthesis of cellpermeable peptide nucleic acids and characterization of their hybridization and uptake properties. Bioorg Med Chem Lett 2006; 16:4931-5. PMID:16809033; http://dx.doi.org/10.1016/j.bmcl.2006.06.052.
-
(2006)
Bioorg Med Chem Lett
, vol.16
, pp. 4931-4935
-
-
Zhou, P.1
Dragulescu-Andrasi, A.2
Bhattacharya, B.3
O'Keefe, H.4
Vatta, P.5
Hyldig-Nielsen, J.J.6
-
30
-
-
33845568513
-
Cellpermeable peptide nucleic acid designed to bind to the 5'-untranslated region of E-cadherin transcript induces potent and sequence-specific antisense effects
-
PMID:17165763
-
Dragulescu-Andrasi A, Rapireddy S, He GF, Bhattacharya B, Hyldig-Nielsen JJ, Zon G, et al. Cellpermeable peptide nucleic acid designed to bind to the 5'-untranslated region of E-cadherin transcript induces potent and sequence-specific antisense effects. J Am Chem Soc 2006; 128:16104-12. PMID:17165763; http://dx.doi.org/10.1021/ja063383v
-
(2006)
J Am Chem Soc
, vol.128
, pp. 16104-16112
-
-
Dragulescu-Andrasi, A.1
Rapireddy, S.2
He, G.F.3
Bhattacharya, B.4
Hyldig-Nielsen, J.J.5
Zon, G.6
-
31
-
-
0032923249
-
Enhanced human immunodeficiency virus infection in macrophages by high-molecular-weight dextran sulfate is associated with conformational changes of gp120 and expression of the CCR5 receptor
-
PMID:10333239
-
Jagodzinski PP, Wierzbicki A, Wustner J, Kaneko Y, Kozbor D. Enhanced human immunodeficiency virus infection in macrophages by high-molecular-weight dextran sulfate is associated with conformational changes of gp120 and expression of the CCR5 receptor. Viral Immunol 1999; 12:23-33. PMID:10333239; http://dx.doi.org/10.1089/vim.1999.12.23.
-
(1999)
Viral Immunol
, vol.12
, pp. 23-33
-
-
Jagodzinski, P.P.1
Wierzbicki, A.2
Wustner, J.3
Kaneko, Y.4
Kozbor, D.5
-
32
-
-
0036178226
-
Expression of CD4 controls the susceptibility of THP-1 cells to infection by R5 and X4 HIV type 1 isolates
-
PMID:11839145
-
Konopka K, Düzgüneş N. Expression of CD4 controls the susceptibility of THP-1 cells to infection by R5 and X4 HIV type 1 isolates. AIDS Res Hum Retroviruses 2002; 18:123-31. PMID:11839145; http://dx.doi.org/10.1089/08892220252779665.
-
(2002)
AIDS Res Hum Retroviruses
, vol.18
, pp. 123-131
-
-
Konopka, K.1
Düzgüneş, N.2
-
33
-
-
44649185556
-
High loading efficiency and tunable release of plasmid DNA encapsulated in submicron particles fabricated from PLGA conjugated with poly-L-lysine
-
PMID:18511145
-
Blum JS, Saltzman WM. High loading efficiency and tunable release of plasmid DNA encapsulated in submicron particles fabricated from PLGA conjugated with poly-L-lysine. J Control Release 2008; 129:66-72. PMID:18511145; http://dx.doi.org/10.1016/j.jconrel. 2008.04.002.
-
(2008)
J Control Release
, vol.129
, pp. 66-72
-
-
Blum, J.S.1
Saltzman, W.M.2
-
34
-
-
66249083866
-
Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA
-
PMID:19404239
-
Woodrow KA, Cu Y, Booth CJ, Saucier-Sawyer JK, Wood MJ, Saltzman WM. Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA. Nat Mater 2009; 8:526-33. PMID:19404239; http://dx.doi.org/10.1038/nmat2444.
-
(2009)
Nat Mater
, vol.8
, pp. 526-533
-
-
Woodrow, K.A.1
Cu, Y.2
Booth, C.J.3
Saucier-Sawyer, J.K.4
Wood, M.J.5
Saltzman, W.M.6
-
35
-
-
84862993281
-
Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphoma. Author summary
-
Babar IA, Cheng CJ, Booth CJ, Liang X, Weidhaas JB, Saltzman WM, et al. Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphoma. Author summary. Proc Natl Acad Sci USA 2012; 109:10140-1; http://dx.doi.org/10.1073/pnas.1201516109.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 10140-10141
-
-
Babar, I.A.1
Cheng, C.J.2
Booth, C.J.3
Liang, X.4
Weidhaas, J.B.5
Saltzman, W.M.6
-
36
-
-
34548133627
-
Complete knockdown of CCR5 by lentiviral vector-expressed siRNAs and protection of transgenic macrophages against HIV-1 infection
-
PMID:17597795
-
Anderson J, Akkina R. Complete knockdown of CCR5 by lentiviral vector-expressed siRNAs and protection of transgenic macrophages against HIV-1 infection. Gene Ther 2007; 14:1287-97. PMID:17597795; http://dx.doi.org/10.1038/sj.gt.3302958.
-
(2007)
Gene Ther
, vol.14
, pp. 1287-1297
-
-
Anderson, J.1
Akkina, R.2
-
37
-
-
0027168725
-
Evaluation of 2'-modified oligonucleotides containing 2'-deoxy gaps as antisense inhibitors of gene expression
-
PMID:8390996
-
Monia BP, Lesnik EA, Gonzalez C, Lima WF, McGee D, Guinosso CJ, et al. Evaluation of 2'-modified oligonucleotides containing 2'-deoxy gaps as antisense inhibitors of gene expression. J Biol Chem 1993; 268:14514-22. PMID:8390996.
-
(1993)
J Biol Chem
, vol.268
, pp. 14514-14522
-
-
Monia, B.P.1
Lesnik, E.A.2
Gonzalez, C.3
Lima, W.F.4
McGee, D.5
Guinosso, C.J.6
-
38
-
-
0000015743
-
Antisense oligonucleotides: Basic concepts and mechanisms
-
PMID:12489851
-
Dias N, Stein CA. Antisense oligonucleotides: basic concepts and mechanisms. Mol Cancer Ther 2002; 1:347-55. PMID:12489851.
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 347-355
-
-
Dias, N.1
Stein, C.A.2
-
39
-
-
0028114572
-
Patterns of intracellular compartmentalization, trafficking and acidification of 5'-fluorescein labeled phosphodiester and phosphorothioate oligodeoxynucleotides in HL60 cells
-
PMID:7937155
-
Tonkinson JL, Stein CA. Patterns of intracellular compartmentalization, trafficking and acidification of 5'-fluorescein labeled phosphodiester and phosphorothioate oligodeoxynucleotides in HL60 cells. Nucleic Acids Res 1994; 22:4268-75. PMID:7937155; http://dx.doi.org/10.1093/nar/22.20.4268.
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 4268-4275
-
-
Tonkinson, J.L.1
Stein, C.A.2
-
40
-
-
0035883088
-
The mononucleotide-dependent, nonantisense mechanism of action of phosphodiester and phosphorothioate oligonucleotides depends upon the activity of an ecto-5'-nucleotidase
-
PMID:11493444
-
Koziolkiewicz M, Gendaszewska E, Maszewska M, Stein CA, Stec WJ. The mononucleotide-dependent, nonantisense mechanism of action of phosphodiester and phosphorothioate oligonucleotides depends upon the activity of an ecto-5'-nucleotidase. Blood 2001; 98:995-1002. PMID:11493444; http://dx.doi.org/10.1182/blood.V98.4.995.
-
(2001)
Blood
, vol.98
, pp. 995-1002
-
-
Koziolkiewicz, M.1
Gendaszewska, E.2
Maszewska, M.3
Stein, C.A.4
Stec, W.J.5
-
41
-
-
0028815149
-
Phosphorothioate oligodeoxynucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors, and remove it from low affinity binding sites on extracellular matrix
-
PMID:7852327
-
Guvakova MA, Yakubov LA, Vlodavsky I, Tonkinson JL, Stein CA. Phosphorothioate oligodeoxynucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors, and remove it from low affinity binding sites on extracellular matrix. J Biol Chem 1995; 270:2620-7. PMID:7852327; http://dx.doi.org/10.1074/jbc.270.6.2620.
-
(1995)
J Biol Chem
, vol.270
, pp. 2620-2627
-
-
Guvakova, M.A.1
Yakubov, L.A.2
Vlodavsky, I.3
Tonkinson, J.L.4
Stein, C.A.5
-
42
-
-
0029052593
-
RNase H is responsible for the non-specific inhibition of in vitro translation by 2'-O-alkyl chimeric oligonucleotides: High affinity or selectivity, a dilemma to design antisense oligomers
-
PMID:7567453
-
Larrouy B, Boiziau C, Sproat B, Toulmé JJ. RNase H is responsible for the non-specific inhibition of in vitro translation by 2'-O-alkyl chimeric oligonucleotides: high affinity or selectivity, a dilemma to design antisense oligomers. Nucleic Acids Res 1995; 23:3434-40. PMID:7567453; http://dx.doi.org/10.1093/nar/23.17.3434.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 3434-3440
-
-
Larrouy, B.1
Boiziau, C.2
Sproat, B.3
Toulmé, J.J.4
-
43
-
-
0027104702
-
Antisense and antigene properties of peptide nucleic acids
-
PMID:1279811
-
Hanvey JC, Peffer NJ, Bisi JE, Thomson SA, Cadilla R, Josey JA, et al. Antisense and antigene properties of peptide nucleic acids. Science 1992; 258:1481-5. PMID:1279811; http://dx.doi.org/10.1126/science.1279811.
-
(1992)
Science
, vol.258
, pp. 1481-1485
-
-
Hanvey, J.C.1
Peffer, N.J.2
Bisi, J.E.3
Thomson, S.A.4
Cadilla, R.5
Josey, J.A.6
-
44
-
-
0029980721
-
Antisense properties of duplex-and triplex-forming PNAs
-
PMID:8602363
-
Knudsen H, Nielsen PE. Antisense properties of duplex-and triplex-forming PNAs. Nucleic Acids Res 1996; 24:494-500. PMID:8602363; http://dx.doi.org/10.1093/nar/24.3.494.
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 494-500
-
-
Knudsen, H.1
Nielsen, P.E.2
-
45
-
-
0030842070
-
Efficient in vitro inhibition of HIV-1 gag reverse transcription by peptide nucleic acid (PNA) at minimal ratios of PNA/RNA
-
PMID:9153317
-
Koppelhus U, Zachar V, Nielsen PE, Liu X, Eugen-Olsen J, Ebbesen P. Efficient in vitro inhibition of HIV-1 gag reverse transcription by peptide nucleic acid (PNA) at minimal ratios of PNA/RNA. Nucleic Acids Res 1997; 25:2167-73. PMID:9153317; http://dx.doi.org/10.1093/nar/25.11.2167.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 2167-2173
-
-
Koppelhus, U.1
Zachar, V.2
Nielsen, P.E.3
Liu, X.4
Eugen-Olsen, J.5
Ebbesen, P.6
-
46
-
-
0029838672
-
In vitro transcription and translation inhibition by anti-promyelocytic leukemia (PML)/retinoic acid receptor α and anti-PML peptide nucleic acid
-
PMID:8695861
-
Gambacorti-Passerini C, Mologni L, Bertazzoli C, le Coutre P, Marchesi E, Grignani F, et al. In vitro transcription and translation inhibition by anti-promyelocytic leukemia (PML)/retinoic acid receptor α and anti-PML peptide nucleic acid. Blood 1996; 88:1411-7. PMID:8695861.
-
(1996)
Blood
, vol.88
, pp. 1411-1417
-
-
Gambacorti-Passerini, C.1
Mologni, L.2
Bertazzoli, C.3
Le Coutre, P.4
Marchesi, E.5
Grignani, F.6
-
47
-
-
0033595778
-
In vitro transcriptional and translational block of the bcl-2 gene operated by peptide nucleic acid
-
PMID:10529398
-
Mologni L, Nielsen PE, Gambacorti-Passerini C. In vitro transcriptional and translational block of the bcl-2 gene operated by peptide nucleic acid. Biochem Biophys Res Commun 1999; 264:537-43. PMID:10529398; http://dx.doi.org/10.1006/bbrc.1999.1548.
-
(1999)
Biochem Biophys Res Commun
, vol.264
, pp. 537-543
-
-
Mologni, L.1
Nielsen, P.E.2
Gambacorti-Passerini, C.3
-
48
-
-
0035830450
-
Inhibition of gene expression inside cells by peptide nucleic acids: Effect of mRNA target sequence, mismatched bases, and PNA length
-
PMID:11141056
-
Doyle DF, Braasch DA, Simmons CG, Janowski BA, Corey DR. Inhibition of gene expression inside cells by peptide nucleic acids: effect of mRNA target sequence, mismatched bases, and PNA length. Biochemistry 2001; 40:53-64. PMID:11141056; http://dx.doi.org/10.1021/bi0020630.
-
(2001)
Biochemistry
, vol.40
, pp. 53-64
-
-
Doyle, D.F.1
Braasch, D.A.2
Simmons, C.G.3
Janowski, B.A.4
Corey, D.R.5
-
49
-
-
0037007998
-
Inhibition of macrophage iNOS by selective targeting of antisense PNA
-
PMID:12081497
-
Chiarantini L, Cerasi A, Fraternale A, Andreoni F, Scarí S, Giovine M, et al. Inhibition of macrophage iNOS by selective targeting of antisense PNA. Biochemistry 2002; 41:8471-7. PMID:12081497; http://dx.doi.org/10.1021/bi020079f
-
(2002)
Biochemistry
, vol.41
, pp. 8471-8477
-
-
Chiarantini, L.1
Cerasi, A.2
Fraternale, A.3
Andreoni, F.4
Scarí, S.5
Giovine, M.6
-
50
-
-
0031763412
-
Drug delivery of antisense molecules to the brain for treatment of Alzheimer's disease and cerebral AIDS
-
PMID:9811482
-
Boado RJ, Tsukamoto H, Pardridge WM. Drug delivery of antisense molecules to the brain for treatment of Alzheimer's disease and cerebral AIDS. J Pharm Sci 1998; 87:1308-15. PMID:9811482; http://dx.doi.org/10.1021/js9800836.
-
(1998)
J Pharm Sci
, vol.87
, pp. 1308-1315
-
-
Boado, R.J.1
Tsukamoto, H.2
Pardridge, W.M.3
-
51
-
-
0034115561
-
Antisense inhibition of δ-opioid receptor gene function in vivo by peptide nucleic acids
-
PMID:10727518
-
Fraser GL, Holmgren J, Clarke PBS, Wahlestedt C. Antisense inhibition of δ-opioid receptor gene function in vivo by peptide nucleic acids. Mol Pharmacol 2000; 57:725-31. PMID:10727518.
-
(2000)
Mol Pharmacol
, vol.57
, pp. 725-731
-
-
Fraser, G.L.1
Holmgren, J.2
Clarke, P.B.S.3
Wahlestedt, C.4
-
52
-
-
0142241350
-
Antisense peptide nucleic acid-mediated knockdown of the p75 neurotrophin receptor delays motor neuron disease in mutant SOD1 transgenic mice
-
PMID:14535957
-
Turner BJ, Cheah IK, Macfarlane KJ, Lopes EC, Petratos S, Langford SJ, et al. Antisense peptide nucleic acid-mediated knockdown of the p75 neurotrophin receptor delays motor neuron disease in mutant SOD1 transgenic mice. J Neurochem 2003; 87:752-63. PMID:14535957; http://dx.doi.org/10.1046/j.1471-4159.2003.02053.x
-
(2003)
J Neurochem
, vol.87
, pp. 752-763
-
-
Turner, B.J.1
Cheah, I.K.2
Macfarlane, K.J.3
Lopes, E.C.4
Petratos, S.5
Langford, S.J.6
-
53
-
-
78650919363
-
Nanoparticles deliver triplex-forming PNAs for site-specific genomic recombination in CD34+ human hematopoietic progenitors
-
PMID:20859257
-
McNeer NA, Chin JY, Schleifman EB, Fields RJ, Glazer PM, Saltzman WM. Nanoparticles deliver triplex-forming PNAs for site-specific genomic recombination in CD34+ human hematopoietic progenitors. Mol Ther 2011; 19:172-80. PMID:20859257; http://dx.doi.org/10.1038/mt.2010.200
-
(2011)
Mol Ther
, vol.19
, pp. 172-180
-
-
McNeer, N.A.1
Chin, J.Y.2
Schleifman, E.B.3
Fields, R.J.4
Glazer, P.M.5
Saltzman, W.M.6
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