A systems analysis of age-related changes in some cardiac aging traits

Biogerontology

Volumn 15, Issue 2, 2014, Pages 139-152

  Govindaraju, D R ^a   Pencina, K M ^b   Raj, D S ^c   Massaro, J M ^b   Carnes, B A ^d   D'Agostino, R B ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b Boston University   (United States)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

Cardiac aging; Developmental plasticity; Exploratory structural equation modeling; Senescence; Systems analysis

Indexed keywords

FIBRINOGEN; LOW DENSITY LIPOPROTEIN; TRIACYLGLYCEROL;

AGED; AGING; ANTHROPOMETRIC PARAMETERS; AORTIC ROOT DIAMETER; ARTICLE; CARDIOVASCULAR PARAMETERS; CARDIOVASCULAR SYSTEM; FEMALE; FIBRINOGEN BLOOD LEVEL; GROUPS BY AGE; HEART LEFT VENTRICLE MASS; HUMAN; LIPOPROTEIN BLOOD LEVEL; MALE; MEAN ARTERIAL PRESSURE; MORPHOLOGICAL TRAIT; NULL HYPOTHESIS; PRIORITY JOURNAL; SENESCENCE; STRUCTURAL EQUATION MODELING; SYSTEM ANALYSIS; TRIACYLGLYCEROL BLOOD LEVEL; ADULT; BIOLOGICAL MODEL; CARDIOVASCULAR FUNCTION; COHORT ANALYSIS; MIDDLE AGED; MULTIVARIATE ANALYSIS; PHYSIOLOGY; SEX DIFFERENCE; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; AGING; CARDIOVASCULAR PHYSIOLOGICAL PHENOMENA; COHORT STUDIES; FEMALE; HUMANS; MALE; MIDDLE AGED; MODELS, CARDIOVASCULAR; MULTIVARIATE ANALYSIS; SEX FACTORS; SYSTEMS ANALYSIS;

EID: 84896394642     PISSN: 13895729     EISSN: 15736768     Source Type: Journal    
DOI: 10.1007/s10522-013-9486-8     Document Type: Article

References (111)

1. Abdelhafiz A (2013) Epidemiology of heart disease. In: Stott DJ, Lowe DO (eds) Pathy's principles and practice of geriatric medicine. Wiley, London
2. Ahmad F, Seidman JG, Seidman CE (2005) The genetic basis for cardiac remodeling. Annu Rev Genomics Hum Genet 6:185-216
3. Aronne LJ (2012) Obesity as a disease: etiology, treatment, and management considerations for the obese patient. Obes Res 10:95S-96S
4. Asparouhov T, Muthén B (2009) Exploratory structural equation modeling. Struct Equ Model 16:397-438
5. Barker DJP (1998) Mothers, babies and health in later life, 2nd edn. Churchill and Livingstone, Edinburgh
6. Barzilai N, Bartke A (2009) Biological approaches to mechanically understand healthy life span extension achieved by calorie restriction and modulation of hormones. J Gerontol A 64:187-191
7. Bateson P, Gluckman P (2011) Plasticity, robustness, development and evolution. Cambridge, Cambridge
8. Bauml MA, Underwood DA (2010) Left ventricular hypertrophy: an overlooked cardiovascular risk factor. Cleve Clin J Med 77(6):381-387
9. Bentler PM (1990) Comparative fit indexes in structural models. Psychol Bull 107:238-246
10. Bentler PM, Dudgeon P (1996) Covariance structure analysis: statistical practice, theory, and directions. Annu Rev Psychol 47:563-592
11. Blom G (1958) Statistical estimates and transformed beta-variables. Wiley, New York
12. Brown DW, Giles WH, Croft JB (2000) Left ventricular hypertrophy as a predictor of coronary heart disease mortality and the effect of hypertension. Am Heart J 140:848-856
13. Browne MW, Cudek R (1993) Alternative ways of assessing model fit. In: Bollen KA, Long JS (eds) Testing structural equation models. Sage, Beverly Hills
14. Burggren WW, Reyna KS (2011) Developmental trajectories, critical windows and phenotypic alteration during cardio-respiratory development. Respir Physiol Neurobiol 178(1):13-21
15. Byars SG (2013) Commentary: haldanes and trends in phenotypic change in humans. Int J Epidemiol. doi: 10.1093/ije/dys245
16. Byars SG, Ewbank D, Govindaraju DR, Stearns SC (2010) Colloquium papers: natural selection in a contemporary human population. Proc Natl Acad Sci USA 107(Suppl 1):1787-1792
17. Carey JP (2003) Longevity: the biology an demography of lifespan. Princeton University Press, Princeton
18. Carnes BA, Witten TM (2013) How long must humans live? J Gerontol 41:793
19. Caspi A, Roberts BW, Shiner RL (2005) Personality development: stability and change. Annu Rev Psychol 56:453-484
20. Caswell H (2009) Stage, age and individual stochasticity in demography. Oikos 118:1763-1782
21. Charlesworth B (1980) Evolution in age-structured populations. Cambridge University Press, Cambridge
22. Charlesworth B (2000) Fisher, Medawar, Hamilton and the evolution of aging. Genetics 156(3):927-931
23. Chen R, Mias GI, Li-Pook-Than J, Jiang L, Lam HY, Miriami E, Karczewski KJ, Hariharan M, Dewey FE, Cheng Y, Clark MJ, Im H, Habegger L, Balasubramanian S, O'Huallachain M, Dudley JT, Hillenmeyer S, Haraksingh R, Sharon D, Euskirchen G, Lacroute P, Bettinger K, Boyle AP, Kasowski M, Grubert F, Seki S, Garcia M, Whirl-Carrillo M, Gallardo M, Blasco MA, Greenberg PL, Snyder P, Klein TE, Altman RB, Butte AJ, Ashley EA, Gerstein M, Nadeau KC, Tang H, Snyder M (2012) Personal omics profiling reveals dynamic molecular and medical phenotypes. Cell 148(6):1293-1307
24. Cheng S, Vasan RS (2011) Advances in the epidemiology of heart failure and left ventricular remodeling. Circulation 124(20):e516-e519
25. Cohen JE (2009) Human population: the next half century. Science 302:1172-1175
26. D'Agostino RB Sr, Vasan RS, Pencina MJ, Wolf PA, Cobain M, Massaro JM, Kannel WB (2008) General cardiovascular risk profile for use in primary care: the Framingham Heart Study. Circulation 117(6):743-753
27. Dai DF, Rabinovitch PS (2009) Cardiac aging in mice and humans: the role of mitochondrial oxidative stress. Trends Cardiovasc Med 19(7):213-220
28. Dawber TR, Meadors GF, Moore FE Jr (1951) Epidemiological approaches to heart disease: the Framingham study. Am J Public Health Nations Health 41(3):279-281
29. Dingemanse NJ, Kazem AJ, Reale D, Wright J (2010) Behavioural reaction norms: animal personality meets individual plasticity. Trends Ecol Evol 25(2):81-89
30. Dunst CJ, Hamby DW, Brookfield J (2007) Modeling the effect of childhood intervention variables on parents and family well-being. J Appl Quant Methods 2:268-288
31. Falconer DS (1952) The problem of environment and selection. Am Nat 86:292-298
32. Ferrari AU, Radaelli A, Centola M (2003) Invited review: aging and the cardiovascular system. J Appl Physiol 95(6):2591-2597
33. Finch C (1990) Longevity, senescence and the genome. University of Chicago, Chicago
34. Finch C (2007) The biology of human longevity: inflammation, nutrition, and aging in the evolution of lifespans. Academic Press, Burlington
35. Fisher LD, Van Belle G (2004) Biostatistics: a methodology for the health sciences. Wiley, New York
36. Flynn JM, O'Leary MN, Zambataro CA, Academia EC, Presley MP, Garrett BJ, Zykovich A, Mooney SD, Strong R, Rosen CJ, Kapahi P, Nelson MD, Kennedy BK, Melov S (2013) Late life rapamycin treatment reverses age-related heart dysfunction. Aging Cell. doi: 10.1111/acel.12109
37. Friedewald WT, Levy RI, Fredrickson DS (1972) Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18(6):499-502
38. Galvani AP, Slatkin M (2004) Intense selection in an age-structured population. Proc R Soc B 271:171-176
39. Glezerman M (2010) Foreword: gender specific medicine environment and biology. Principles of gender specific medicine. Elsevier, London
40. Gluckman PD, Hanson MA (2007) Developmental plasticity and human disease: research directions. J Intern Med 261:461-471
41. Gluckman PD, Hanson MA, Spencer HG, Bateson P (2005) Environmental influences during development and their consequences for health and disease: Implications for the interpretation of empirical studies. Proc R Soc B 272:671-677
42. Gluckman PD, Hanson MA, Low FM (2011) The role of developmental plasticity and epigenetics in human health. Birth Defects Res C 93(1):12-18
43. Govindaraju DR, Cupples LA, Kannel WB, O'Donnell CJ, Atwood LD, D'Agostino RB, Fox CS, Larson M, Levy D, Murabito J, Vasan RS, Splansky GL, Wolf PA, Benjamin EJ (2008) Genetics of the Framingham Heart Study population. Adv Genet 62:33-65
44. Grace JB (2006) Structural equation modeling and natural systems. Cambridge University Press, Cambridge
45. Horiuchi S (ed) (2006) Causes of death among the oldest - old: age-related changes in the cause-of-death distribution. Human logevity, individual life duration and the growth of the oldest-old population. Springer, New York
46. Houle D, Govindaraju DR, Omholt S (2010) Phenomics: the next challenge. Nat Rev Genet 11(12):855-866
47. Huang C, Xiong C, Kornfeld K (2004) Measurements of age-related changes of physiological processes that predict lifespan of Caenorhabditis elegans. Proc Natl Acad Sci USA 101(21):8084-8089
48. Hughes KA, Charlesworth B (1994) A genetic analysis of senescence in Drosophila. Nature 367:64-66
49. Ito MK, McGowan MP, Moriarty PM (2011) Management of familial hypercholesterolemias in adult patients: recommendations from the National Lipid Association Expert Panel on Familial Hypercholesterolemia. J Clin Lipidol 5(3 Suppl):S38-S45
50. Jones JH (2009) The force of selection on the human life cycle. Evol Hum Behav 30(5):305-314
51. Kannel WB, D'Agostino RB (1995) The importance of cardiovascular risk factors in the elderly. Am J Geriatr Cardiol 4(2):10-23
52. Kannel WB, Feinleib M, McNamara PM, Garrison RJ, Castelli WP (1979) An investigation of coronary heart disease in families. The Framingham offspring study. Am J Epidemiol 110(3):281-290
53. Karavidas A, Lazaros G, Tsiachris D, Pyrgakis V (2010) Aging and the cardiovascular system. Hellenic J Cardiol 51(5):421-427
54. Khattar RS, Swales JD, Dore C, Senior R, Lahiri A (2001) Effect of aging on the prognostic significance of ambulatory systolic, diastolic, and pulse pressure in essential hypertension. Circulation 104(7):783-789
55. Kirkwood TB (2011) Systems biology of ageing and longevity. Philos Trans R Soc Lond B 366(1561):64-70
56. Kline RB (ed) (2012) Assumptions in structural equation modeling. Gulford, New York
57. Kline RB (ed) (2013) Exploratory and confirmatory factor analysis. Applied quantitative analysis in the social sciences. Rouledge, New York
58. Kreiger N, Chen JT, Waterman PD, Kosheleva A, Beckfield J (2012) History, haldanes and health inequities: exploring phenotypic changes in body size by generation and income level in the US-born White and Black non-Hispanic populations 1959-1962 to 2005-2008. Int J Epidemiol 41:000
59. Kuh D, Ben-Shlomo Y, Lynch J, Hallqvist J, Power C (2003) Life course epidemiology. J Epidemiol Community Health 57(10):778-783
60. Lakatta EG (2002) Age-associated cardiovascular changes in health: impact on cardiovascular disease in older persons. Heart Fail Rev 7(1):29-49
61. Lakatta EG (2003) Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part III: cellular and molecular clues to heart and arterial aging. Circulation 107(3):490-497
62. Leips J, Gilliagan P, Mackay TFC (2006) Quantitative trait loci with age-specific effects on fecundity in Drosophila melanogaster. Genetics 172:1595-1605
63. Li CC (1975) Path analysis: a primer. Boxwood, Pacific Grove
64. Liao JK, Laufs U (2005) Pleiotropic effects of statins. Annu Rev Pharmacol Toxicol 45:89-118
65. Lieberman DE, McBratney BM, Krovitz G (2002) The evolution and development of cranial form in Homosapiens. Proc Natl Acad Sci USA 99(3):1134-1139
66. Lloyd-Jones DM, Wang TJ, Leip EP, Larson MG, Levy D, Vasan RS, D'Agostino RB, Massaro JM, Beiser A, Wolf PA, Benjamin EJ (2004) Lifetime risk for development of atrial fibrillation: the Framingham Heart Study. Circulation 110(9):1042-1046
67. Lynch M (1988) Path analysis of ontogenetic data. In: Ebenman B, Person L (eds) Size-structured populations. Springer, Berlin
68. Marsh HW, Muthén B, Asparouhov T, Lüdtke O, Robitzsch A, Morin AJ, Trautwein US (2009) Exploratory structural equation modeling, integrating CFA and EFA: application to students' evaluations of university teaching. Struct Equ Model 16:439-476
69. Marsh HW, Nagengast B, Morin AJS (2012) Measurement invariance of big five factors over the life span: ESEM tests of gender, age, plasticity, maturity and La Dolce vita effects. Dev Psychol 49:1194
70. Medland S, Neale MC (2009) An integrated phenomic approach to multivariate allelic association. Eur J Hum Genet 18:233-239
71. Milot E, Mayer FM, Nussey DH, Boisvert M, Pelletier F, Reale D (2011) Evidence for evolution in response to natural selection in a contemporary human population. Proc Natl Acad Sci USA 108(41):17040-17045
72. Moczek AP, Sultan S, Foster S, Ledon-Rettig C, Dworkin I, Nijhout HF, Abouheif E, Pfennig DW (2011) The role of developmental plasticity in evolutionary innovation. Proc Biol Sci 278(1719):2705-2713
73. Moller AP (1997) Stress, developmental stability and sexual selection. EXS 83:255-268
74. Morin AJS, Marsh HW, Nagengast B (2013) Exploratory structural equation modeling. In: Hancock GR, Mueller RO (eds) Structural equation modeling: a second course. Information Age, Charlotte
75. Nadeau JH, Burrage LC, Restivo J, Pao YH, Churchill G, Hoit BD (2003) Pleiotropy, homeostasis, and functional networks based on assays of cardiovascular traits in genetically randomized populations. Genome Res 13(9):2082-2091
76. Nijland MJ, Ford SP, Nathanielsz PW (2008) Prenatal origins of adult disease. Curr Opin Obstet Gynecol 20(2):132-138
77. Nochajski SM (ed) (2000) The impact of age-related changes on the functioning of older adults with developmental disabilities. Developmental disability: current research, programming, and practice implications. The Haworth Press Inc., Binghamton
78. Okin PM, Devereux RB, Jern S, Kjeldsen SE, Julius S, Nieminen MS, Snapinn S, Harris KE, Aurup P, Edelman JM, Wedel H, Lindholm LH, Dahlof B (2004) Regression of electrocardiographic left ventricular hypertrophy during antihypertensive treatment and the prediction of major cardiovascular events. JAMA 292(19):2343-2349
79. Olivetti G, Giordano G, Corradi D, Melissari M, Lagrasta C, Gambert SR, Anversa P (1995) Gender differences and aging: effects on the human heart. J Am Coll Cardiol 26(4):1068-1079
80. O'Rourke MF, Hashimoto J (2007) Mechanical factors in arterial aging: a clinical perspective. J Am Coll Cardiol 50(1):1-13
81. Partridge L (2010) The new biology of aging. Philos Trans R Soc B 365:147-154
82. Partridge L, Barton NH (1993) Optimality, mutation and the evolution of aging. Nature 362:305-311
83. Perlman RL (2013) Evolution and medicine. Oxford University Press, Oxford
84. Pi-Sunyer FX (2012) The obesity epidemic: pathophysiology and consequences of obesity. Obesity 10:97S-104S
85. Polak M, Tomkins JL (2013) Developmental selection against developmental instability: a direct demonstration. Biol Lett 9(2):20121081
86. Roeters van Lennep JE, Waesterveld HT, Erkelens DW, van der Wall EE (2002) Risk factors for coronary heart disease: implications of gender. Cardiovasc Res 53:538-549
87. Roff DA (2007) Contributions of genomics to life-history theory. Nat Rev Genet 8:116-125
88. Rosamond W, Flegal K, Furie K, Go A, Greenlund K, Haase N, Hailpern SM, Ho M, Howard V, Kissela B, Kittner S, Lloyd-Jones D, McDermott M, Meigs J, Moy C, Nichol G, O'Donnell C, Roger V, Sorlie P, Steinberger J, Thom T, Wilson M, Hong Y (2008) Heart disease and stroke statistics-2008 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 117(4):e25-e146
89. Sayer AA, Barker D (2002) The early environment, developmental plasticity and aging. Rev Clin Gerontol 12:205-211
90. Snell-Rood EC, Van Dyken JD, Cruickshank T, Wade MJ, Moczek AP (2010) Toward a population genetic framework of developmental evolution: the costs, limits, and consequences of phenotypic plasticity. BioEssays 32(1):71-81
91. Snoke MS, Promislow DE (2003) Quantitative genetic tests of recent senescence theory: age specific mortality and male fertility in Drosophila mealnogaster. Heredity 91:546-556
92. Soltow QA, Jones DP, Promislow DE (2010) A network perspective on metabolism and aging. Integr Comp Biol 50(5):844-854
93. Stamler J, Vaccaro O, Neaton JD, Wentworth D (1993) Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the multiple risk factor intervention trial. Diabetes Care 16(2):434-444
94. Stearns SC (1989) The evolutionary significance of phenotypic plasticity. Bioscience 39:436-445
95. Stearns SC, Allal CN, Mace R (2008) Life history theory and human development. In: Krebs D (ed) Foundations of evolutionary psychology. Psychology, New York
96. Stearns SC, Byars SG, Govindaraju DR, Ewbank D (2010) Measuring selection in contemporary human populations. Nat Rev Genet 11(9):611-622
97. Stearns SC, Govindaraju DR, Ewbank D, Byars SG (2012) Constraints on the coevolution of contemporary human males and females. Proc Biol Sci 279:4836-4844
98. Stengard JH, Dyson G, Frikke-Schmidt R, Tybjaerg-Hansen A, Nordestgaard BG, Sing CF (2010) Context-dependent associations between variation in risk of ischemic heart disease and variation in the 5′ promoter region of the apolipoprotein E gene in Danish women. Circ Cardiovasc Genet 3(1):22-30
99. Strehler BL (1959) Origin and comparison of the effects of time and high-energy radiations on living systems. Q Rev Biol 34(2):117-142
100. Swynghedauw B (2006) Phenotypic plasticity of adult myocardium: molecular mechanisms. J Exp Biol 209(Pt 12):2320-2327
101. Vaupel JW, Manton KG, Stallard E (1979) The impact of heterogeneity in individual frailty on the dynamics of mortality. Demography 16(3):439-454
102. Vijg J (2007) Aging of the Genome: the dual role of the DNA in life an death. Oxford University Press, Oxford
103. Wachter KW, Evans SN, Steinsaltz D (2013) The age-specific force of natural selection and biodemographic walls of death. Proc Natl Acad Sci USA 110(25):10141-10146
104. Wagner GP (1996) Homologues, natural kinds and the evolution of modularity. Integr Comp Biol 36:36-43
105. Wagner GP, Pavlicev M, Cheverud JM (2007) The road to modularity. Nat Rev Genet 8(12):921-931
106. Wei JY (1992) Age and the cardiovascular system. N Engl J Med 327(24):1735-1739
107. Williams GC (1957) Pleiotropy, natural selection and the evolution of senescence. Evolution 11:398-411
108. Wright S (1921) Correlation and causation. J Agric Res 20:557-585
109. Wright S (1934) The method of path coefficients. Ann Math Stat 5:161-215
110. Yamada Y (1962) Genotype by environment interaction and genetic correlation of the same trait under different environments. Jpn J Genet 37:498-509
111. Zheng L, Sun Z, Li J, Zhang R, Zhang X, Liu S, Xu C, Hu D, Sun Y (2008) Pulse pressure and mean arterial pressure in relation to ischemic stroke among patients with uncontrolled hypertension in rural areas of China. Stroke 39(7):1932-1937