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Volumn 9, Issue 2, 2014, Pages

RNA aptamer probes as optical imaging agents for the detection of amyloid plaques

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; APTAMER; RNA APTAMER BETA55; UNCLASSIFIED DRUG; RNA PROBE;

EID: 84896354009     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0089901     Document Type: Article
Times cited : (40)

References (52)
  • 1
    • 0032860385 scopus 로고    scopus 로고
    • Aptamers: An emerging class of molecules that rival antibodies in diagnostics
    • Jayasena SD (1999) Aptamers: an emerging class of molecules that rival antibodies in diagnostics. Clin Chem 45: 1628-1650.
    • (1999) Clin Chem , vol.45 , pp. 1628-1650
    • Jayasena, S.D.1
  • 2
    • 14544295783 scopus 로고    scopus 로고
    • Aptamers: An emerging class of therapeutics
    • DOI 10.1146/annurev.med.56.062904.144915
    • Nimjee SM, Rusconi CP, Sullenger BA (2005) Aptamers: an emerging class of therapeutics. Annu Rev Med 56: 555-583. (Pubitemid 40299797)
    • (2005) Annual Review of Medicine , vol.56 , pp. 555-583
    • Nimjee, S.M.1    Rusconi, C.P.2    Sullenger, B.A.3
  • 3
    • 33846914204 scopus 로고    scopus 로고
    • Gene therapy progress and prospects: RNA aptamers
    • DOI 10.1038/sj.gt.3302900, PII 3302900
    • Que-Gewirth NS, Sullenger BA (2007) Gene therapy progress and prospects: RNA aptamers. Gene Ther 14: 283-291. (Pubitemid 46231922)
    • (2007) Gene Therapy , vol.14 , Issue.4 , pp. 283-291
    • Que-Gewirth, N.S.1    Sullenger, B.A.2
  • 4
    • 70349272617 scopus 로고    scopus 로고
    • Therapeutic applications of DNA and RNA aptamers
    • Thiel KW, Giangrande PH (2009) Therapeutic applications of DNA and RNA aptamers. Oligonucleotides 19: 209-222.
    • (2009) Oligonucleotides , vol.19 , pp. 209-222
    • Thiel, K.W.1    Giangrande, P.H.2
  • 5
    • 0025074907 scopus 로고
    • In vitro selection of RNA molecules that bind specific ligands
    • Ellington AD, Szostak JW (1990) In vitro selection of RNA molecules that bind specific ligands. Nature 346: 818-822.
    • (1990) Nature , vol.346 , pp. 818-822
    • Ellington, A.D.1    Szostak, J.W.2
  • 6
    • 0025194307 scopus 로고
    • Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
    • Tuerk C, Gold L (1990) Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science 249: 505-510.
    • (1990) Science , vol.249 , pp. 505-510
    • Tuerk, C.1    Gold, L.2
  • 7
    • 0028224199 scopus 로고
    • High-resolution molecular discrimination by RNA
    • Jenison RD, Gill SC, Pardi A, Polisky B (1994) High-resolution molecular discrimination by RNA. Science 263: 1425-1429. (Pubitemid 24137828)
    • (1994) Science , vol.263 , Issue.5152 , pp. 1425-1429
    • Jenison, R.D.1    Gill, S.C.2    Pardi, A.3    Polisky, B.4
  • 8
    • 0033790673 scopus 로고    scopus 로고
    • Escort aptamers: A delivery service for diagnosis and therapy
    • Hicke BJ, Stephens AW (2000) Escort aptamers: a delivery service for diagnosis and therapy. J Clin Invest 106: 923-928.
    • (2000) J Clin Invest , vol.106 , pp. 923-928
    • Hicke, B.J.1    Stephens, A.W.2
  • 9
    • 33747164245 scopus 로고    scopus 로고
    • Aptamers come of age - At last
    • DOI 10.1038/nrmicro1458, PII NRMICRO1458
    • Bunka DHJ, Stockley PG (2006) Aptamers come of age - at last. Nat Rev Microbiol 4: 588-596. (Pubitemid 44317021)
    • (2006) Nature Reviews Microbiology , vol.4 , Issue.8 , pp. 588-596
    • Bunka, D.H.J.1    Stockley, P.G.2
  • 12
    • 34248190279 scopus 로고    scopus 로고
    • A beta oligomers - A decade of discovery
    • Walsh DM, Selkoe DJ (2007) A beta oligomers - a decade of discovery. J Neurochem 101: 1172-1184.
    • (2007) J Neurochem , vol.101 , pp. 1172-1184
    • Walsh, D.M.1    Selkoe, D.J.2
  • 13
    • 79952563494 scopus 로고    scopus 로고
    • Low-n oligomers as therapeutic targets of Alzheimer's disease
    • Ono K, Yamada M (2011) Low-n oligomers as therapeutic targets of Alzheimer's disease. J Neurochem 117: 19-28.
    • (2011) J Neurochem , vol.117 , pp. 19-28
    • Ono, K.1    Yamada, M.2
  • 14
    • 11544279355 scopus 로고    scopus 로고
    • Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins
    • Lambert MP, Barlow AK, Chromy BA, Edwards C, Freed R, et al. (1998) Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins. Proc Natl Acad Sci USA 95: 6448-6453.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6448-6453
    • Lambert, M.P.1    Barlow, A.K.2    Chromy, B.A.3    Edwards, C.4    Freed, R.5
  • 15
    • 33846633336 scopus 로고    scopus 로고
    • Abeta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease
    • DOI 10.1523/JNEUROSCI.3501-06.2007
    • Lacor PN, Buniel MC, Furlow PW, Clemente AS, Velasco PT, et al. (2007) Abeta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease. J Neurosci 27: 796-807. (Pubitemid 46174498)
    • (2007) Journal of Neuroscience , vol.27 , Issue.4 , pp. 796-807
    • Lacor, P.N.1    Buniel, M.C.2    Furlow, P.W.3    Clemente, A.S.4    Velasco, P.T.5    Wood, M.6    Viola, K.L.7    Klein, W.L.8
  • 16
    • 33947314641 scopus 로고    scopus 로고
    • Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway
    • DOI 10.1523/JNEUROSCI.4970-06.2007
    • Shankar GM, Bloodgood BL, Townsend M, Walsh DM, Selkoe DJ, et al. (2007) Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway. J Neurosci 27: 2866-2875. (Pubitemid 46438992)
    • (2007) Journal of Neuroscience , vol.27 , Issue.11 , pp. 2866-2875
    • Shankar, G.M.1    Bloodgood, B.L.2    Townsend, M.3    Walsh, D.M.4    Selkoe, D.J.5    Sabatini, B.L.6
  • 17
    • 49149124343 scopus 로고    scopus 로고
    • Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
    • Shankar GM, Li S, Mehta TH, Garcia-Munoz A, Shepardson NE, et al. (2008) Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory. Nat Med 14: 837-842.
    • (2008) Nat Med , vol.14 , pp. 837-842
    • Shankar, G.M.1    Li, S.2    Mehta, T.H.3    Garcia-Munoz, A.4    Shepardson, N.E.5
  • 18
    • 33645038471 scopus 로고    scopus 로고
    • A specific amyloid-beta protein assembly in the brain impairs memory
    • Lesné S, Koh MT, Kotilinek L, Kayed R, Glabe CG, et al. (2006) A specific amyloid-beta protein assembly in the brain impairs memory. Nature 440: 352-357.
    • (2006) Nature , vol.440 , pp. 352-357
    • Lesné, S.1    Koh, M.T.2    Kotilinek, L.3    Kayed, R.4    Glabe, C.G.5
  • 19
    • 38949208262 scopus 로고    scopus 로고
    • Plaque-bearing mice with reduced levels of oligomeric amyloid-beta assemblies have intact memory function
    • Lesné S, Kotilinek L, Ashe KH (2008) Plaque-bearing mice with reduced levels of oligomeric amyloid-beta assemblies have intact memory function. Neuroscience 151: 745-749.
    • (2008) Neuroscience , vol.151 , pp. 745-749
    • Lesné, S.1    Kotilinek, L.2    Ashe, K.H.3
  • 20
    • 62649174753 scopus 로고    scopus 로고
    • Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques
    • Koffie RM, Meyer-Luehmann M, Hashimoto T, Adams KW, Mielke ML, et al. (2009) Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques. Proc Natl Acad Sci USA 106: 4012-4017.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 4012-4017
    • Koffie, R.M.1    Meyer-Luehmann, M.2    Hashimoto, T.3    Adams, K.W.4    Mielke, M.L.5
  • 21
    • 84863192724 scopus 로고    scopus 로고
    • Apolipoprotein E4 effects in Alzheimer's disease are mediated by synaptotoxic oligomeric amyloid-β
    • Koffie RM, Hashimoto T, Tai H-C, Kay KR, Serrano-Pozo A, et al. (2012) Apolipoprotein E4 effects in Alzheimer's disease are mediated by synaptotoxic oligomeric amyloid-β. Brain 135: 2155-2168.
    • (2012) Brain , vol.135 , pp. 2155-2168
    • Koffie, R.M.1    Hashimoto, T.2    Tai, H.-C.3    Kay, K.R.4    Serrano-Pozo, A.5
  • 22
    • 79955524573 scopus 로고    scopus 로고
    • Brain oligomeric β-amyloid but not total amyloid plaque burden correlates with neuronal loss and astrocyte inflammatory response in amyloid precursor protein/tau transgenic mice
    • DaRocha-Souto B, Scotton TC, Coma M, Serrano-Pozo A, Hashimoto T, et al. (2011) Brain oligomeric β-amyloid but not total amyloid plaque burden correlates with neuronal loss and astrocyte inflammatory response in amyloid precursor protein/tau transgenic mice. J Neuropathol Exp Neurol 70: 360-376.
    • (2011) J Neuropathol Exp Neurol , vol.70 , pp. 360-376
    • DaRocha-Souto, B.1    Scotton, T.C.2    Coma, M.3    Serrano-Pozo, A.4    Hashimoto, T.5
  • 23
    • 33749507375 scopus 로고    scopus 로고
    • Conformation-Dependent Anti-Amyloid Oligomer Antibodies
    • DOI 10.1016/S0076-6879(06)13017-7, PII S0076687906130177, Amyloid, Prions, and Other Protein Aggregates, Part C
    • Kayed R, Glabe CG (2006) Conformation-dependent anti-amyloid oligomer antibodies. Meth Enzymol 413: 326-344. (Pubitemid 44528698)
    • (2006) Methods in Enzymology , vol.413 , pp. 326-344
    • Kayed, R.1    Glabe, C.G.2
  • 25
    • 0028170719 scopus 로고
    • Soluble amyloid beta-protein in the cerebrospinal fluid from patients with Alzheimer's disease, vascular dementia and controls
    • DOI 10.1016/0022-510X(94)90140-6
    • PirttiläT, Kim KS, Mehta PD, Frey H, Wisniewski HM (1994) Soluble amyloid beta-protein in the cerebrospinal fluid from patients with Alzheimer's disease, vascular dementia and controls. J Neurol Sci 127: 90-95. (Pubitemid 24372529)
    • (1994) Journal of the Neurological Sciences , vol.127 , Issue.1 , pp. 90-95
    • Pirttila, T.1    Kim, K.S.2    Mehta, P.D.3    Frey, H.4    Wisniewski, H.M.5
  • 26
    • 0242668337 scopus 로고    scopus 로고
    • Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
    • DOI 10.1126/science.1079469
    • Kayed R, Head E, Thompson JL, McIntire TM, Milton SC, et al. (2003) Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science 300: 486-489. (Pubitemid 36444329)
    • (2003) Science , vol.300 , Issue.5618 , pp. 486-489
    • Kayed, R.1    Head, E.2    Thompson, J.L.3    McIntire, T.M.4    Milton, S.C.5    Cotman, C.W.6    Glabel, C.G.7
  • 27
    • 58249104047 scopus 로고    scopus 로고
    • Single-domain antibodies recognize selectively small oligomeric forms of amyloid beta, prevent Abeta-induced neurotoxicity and inhibit fibril formation
    • Lafaye P, Achour I, England P, Duyckaerts C, Rougeon F (2009) Single-domain antibodies recognize selectively small oligomeric forms of amyloid beta, prevent Abeta-induced neurotoxicity and inhibit fibril formation. Mol Immunol 46: 695-704.
    • (2009) Mol Immunol , vol.46 , pp. 695-704
    • Lafaye, P.1    Achour, I.2    England, P.3    Duyckaerts, C.4    Rougeon, F.5
  • 29
    • 36749078121 scopus 로고    scopus 로고
    • Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers
    • Kayed R, Head E, Sarsoza F, Saing T, Cotman CW, et al. (2007) Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers. Mol Neurodegeneration 2: 18.
    • (2007) Mol Neurodegeneration , vol.2 , pp. 18
    • Kayed, R.1    Head, E.2    Sarsoza, F.3    Saing, T.4    Cotman, C.W.5
  • 31
    • 33645220400 scopus 로고    scopus 로고
    • Targeting amyloid-beta peptide (Abeta) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Abeta precursor protein (APP) transgenic mice
    • DOI 10.1074/jbc.M511018200
    • Lee EB, Leng LZ, Zhang B, Kwong L, Trojanowski JQ, et al. (2006) Targeting amyloid-beta peptide (Abeta) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Abeta precursor protein (APP) transgenic mice. J Biol Chem 281: 4292-4299. (Pubitemid 43847859)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.7 , pp. 4292-4299
    • Lee, E.B.1    Leng, L.Z.2    Zhang, B.3    Kwong, L.4    Trojanowski, J.Q.5    Abel, T.6    Lee, V.M.-Y.7
  • 32
    • 0035106780 scopus 로고    scopus 로고
    • Imaging of amyloid-beta deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy
    • DOI 10.1038/85525
    • Bacskai BJ, Kajdasz ST, Christie RH, Carter C, Games D, et al. (2001) Imaging of amyloid-beta deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy. Nat Med 7: 369-372. (Pubitemid 32224356)
    • (2001) Nature Medicine , vol.7 , Issue.3 , pp. 369-372
    • Bacskai, B.J.1    Kajdasz, S.T.2    Christie, R.H.3    Carter, C.4    Games, D.5    Seubert, P.6    Schenk, D.7    Hyman, B.T.8
  • 36
    • 70450159254 scopus 로고    scopus 로고
    • RNA aptamers generated against oligomeric Abeta40 recognize common amyloid aptatopes with low specificity but high sensitivity
    • Rahimi F, Murakami K, Summers JL, Chen C-HB, Bitan G (2009) RNA aptamers generated against oligomeric Abeta40 recognize common amyloid aptatopes with low specificity but high sensitivity. PLoS ONE 4: e7694.
    • (2009) PLoS ONE , vol.4
    • Rahimi, F.1    Murakami, K.2    Summers, J.L.3    Chen, C.-H.B.4    Bitan, G.5
  • 37
    • 68949113769 scopus 로고    scopus 로고
    • RNA aptamers selected against amyloid beta-peptide (Abeta) inhibit the aggregation of Abeta
    • Takahashi T, Tada K, Mihara H (2009) RNA aptamers selected against amyloid beta-peptide (Abeta) inhibit the aggregation of Abeta. Molecular Biosystems 5: 986-991.
    • (2009) Molecular Biosystems , vol.5 , pp. 986-991
    • Takahashi, T.1    Tada, K.2    Mihara, H.3
  • 38
    • 84863469025 scopus 로고    scopus 로고
    • Selection of DNA aptamers that recognize α-synuclein oligomers using a competitive screening method
    • Tsukakoshi K, Abe K, Sode K, Ikebukuro K (2012) Selection of DNA aptamers that recognize α-synuclein oligomers using a competitive screening method. Anal Chem 84: 5542-5547.
    • (2012) Anal Chem , vol.84 , pp. 5542-5547
    • Tsukakoshi, K.1    Abe, K.2    Sode, K.3    Ikebukuro, K.4
  • 40
    • 0033591465 scopus 로고    scopus 로고
    • Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure
    • DOI 10.1006/jmbi.1999.2700
    • Mathews DH, Sabina J, Zuker M, Turner DH (1999) Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure. J Mol Biol 288: 911-940. (Pubitemid 29248642)
    • (1999) Journal of Molecular Biology , vol.288 , Issue.5 , pp. 911-940
    • Mathews, D.H.1    Sabina, J.2    Zuker, M.3    Turner, D.H.4
  • 43
    • 22144462135 scopus 로고    scopus 로고
    • Neurotoxic protein oligomers - What you see is not always what you get
    • DOI 10.1080/13506120500106958
    • Bitan G, Fradinger EA, Spring SM, Teplow DB (2005) Neurotoxic protein oligomers-what you see is not always what you get. Amyloid 12: 88-95. (Pubitemid 40978716)
    • (2005) Amyloid , vol.12 , Issue.2 , pp. 88-95
    • Bitan, G.1    Fradinger, E.A.2    Spring, S.M.3    Teplow, D.B.4
  • 44
    • 84876216611 scopus 로고    scopus 로고
    • Oligomers, fact or artefact? SDS-PAGE induces dimerization of β-amyloid in human brain samples
    • Watt AD, Perez KA, Rembach A, Sherrat NA, Hung LW, et al. (2013) Oligomers, fact or artefact? SDS-PAGE induces dimerization of β-amyloid in human brain samples. Acta Neuropathol 125: 549-564.
    • (2013) Acta Neuropathol , vol.125 , pp. 549-564
    • Watt, A.D.1    Perez, K.A.2    Rembach, A.3    Sherrat, N.A.4    Hung, L.W.5
  • 46
    • 64549140676 scopus 로고    scopus 로고
    • Structural characterization of a soluble amyloid beta-peptide oligomer
    • Yu L, Edalji R, Harlan JE, Holzman TF, Lopez AP, et al. (2009) Structural characterization of a soluble amyloid beta-peptide oligomer. Biochemistry 48: 1870-1877.
    • (2009) Biochemistry , vol.48 , pp. 1870-1877
    • Yu, L.1    Edalji, R.2    Harlan, J.E.3    Holzman, T.F.4    Lopez, A.P.5
  • 50
    • 0036707495 scopus 로고    scopus 로고
    • BetaAPP and furin mRNA concentrates in immature senile plaques in the brain of Alzheimer patients
    • Marcinkiewicz M (2002) BetaAPP and furin mRNA concentrates in immature senile plaques in the brain of Alzheimer patients. J Neuropathol Exp Neurol 61: 815-829.
    • (2002) J Neuropathol Exp Neurol , vol.61 , pp. 815-829
    • Marcinkiewicz, M.1


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