The resveratrol attenuates ethanol-induced hepatocyte apoptosis via inhibiting ER-related caspase-12 activation and PDE activity in vitro

Alcoholism: Clinical and Experimental Research

Volumn 38, Issue 3, 2014, Pages 683-693

  Liu, L Q ^a   Fan, Z Q ^a   Tang, Y F ^a   Ke, Z J ^a  

^a Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

Author keywords

Apoptosis; Caspase 12 activation; Endoplasmic reticulum stress; Ethanol; Resveratrol

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ALCOHOL; ALCOHOL DEHYDROGENASE; ALCOHOL DEHYDROGENASE 2; ALDEHYDE DEHYDROGENASE ISOENZYME 2; CASPASE 12; CASPASE 3; CYCLIC NUCLEOTIDE; GLUCOSE REGULATED PROTEIN 78; INITIATION FACTOR 2ALPHA; LIPOCORTIN 5; PHOSPHODIESTERASE; PROTEIN IRE1; RESVERATROL; SIRTUIN 1; UNCLASSIFIED DRUG; VASOPRESSIN;

AMPLIFIED PRODUCT LENGTH POLYMORPHISM; APOPTOSIS; ARTICLE; CELL ASSAY; CELL LINE; CELL LYSATE; CELL VIABILITY; CELL VIABILITY ASSAY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME ACTIVITY; GENOTYPE; HUMAN; HUMAN CELL; HYPOTHESIS; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOFLUORESCENCE TEST; IN VITRO STUDY; LIVER CELL; MTT ASSAY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROPIDIUM IODIDE ASSAY; PROTEIN DETERMINATION; SIGNAL TRANSDUCTION; SILENT GENE; WESTERN BLOTTING;

APOPTOSIS; CASPASE-12 ACTIVATION; ENDOPLASMIC RETICULUM STRESS; ETHANOL; RESVERATROL;

ALCOHOL DEHYDROGENASE; ALDEHYDE DEHYDROGENASE; APOPTOSIS; CASPASE 12; CASPASE INHIBITORS; CELL LINE; CENTRAL NERVOUS SYSTEM DEPRESSANTS; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ETHANOL; HEPATOCYTES; HUMANS; PHOSPHODIESTERASE INHIBITORS; PHOSPHORIC DIESTER HYDROLASES; SIRTUIN 1; STILBENES;

EID: 84896318969     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/acer.12311     Document Type: Article

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