GABAA receptor dephosphorylation followed by internalization is coupled to neuronal death in in vitro ischemia

Neurobiology of Disease

Volumn 65, Issue , 2014, Pages 220-232

  Mele, Miranda ^a,b,c   Ribeiro, Luís ^a,b   Inácio, Ana R ^d   Wieloch, Tadeusz ^d   Duarte, Carlos B ^a,b  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c UNIVERSITY OF COIMBRA   (Portugal)

^d LUND UNIVERSITY   (Sweden)

Author keywords

Brain ischemia; Calpains; Gephyrin; Neuroprotection; Receptor traffic

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR BETA3; CALPAIN; CLATHRIN; GEPHYRIN; GLUTAMATE RECEPTOR; MESSENGER RNA; SERINE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN ISCHEMIA; CELL DEATH; CONTROLLED STUDY; DISSOCIATION; EMBRYO; ENDOCYTOSIS; GABAERGIC TRANSMISSION; HIPPOCAMPAL NEURONAL CULTURE; IN VITRO STUDY; IN VIVO STUDY; INTERNALIZATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RAT; RECEPTOR DOWN REGULATION; RECEPTOR INTERNALIZATION; SYNAPTIC INHIBITION;

BRAIN ISCHEMIA; CALPAINS; GABA(A) RECEPTORS; GEPHYRIN; NEUROPROTECTION; RECEPTOR TRAFFIC;

ANIMALS; ANOXIA; CALPAIN; CELL DEATH; CELLS, CULTURED; CYSTEINE PROTEINASE INHIBITORS; DISEASE MODELS, ANIMAL; EMBRYO, MAMMALIAN; EXCITATORY AMINO ACID ANTAGONISTS; GENE EXPRESSION REGULATION; GLUCOSE; HIPPOCAMPUS; HUMANS; INFARCTION, MIDDLE CEREBRAL ARTERY; NEURONS; PHOSPHORYLATION; PROTEIN SUBUNITS; RATS; RATS, WISTAR; RECEPTORS, GABA-B; TIME FACTORS;

EID: 84896313006     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2014.01.019     Document Type: Article

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