Sequential Release of GABA by Exocytosis and Reversed Uptake Leads to Neuronal Swelling in Simulated Ischemia of Hippocampal Slices

Journal of Neuroscience

Volumn 24, Issue 15, 2004, Pages 3837-3849

  Allen, Nicola J ^a   Rossi, David J ^b   Attwell, David ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Chloride; Excitotoxicity; GABA; GAT 1; Ischemia; Reversed uptake; Transporter

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; CHLORIDE ION; EXCITOTOXIN; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

4 AMINOBUTYRIC ACID RELEASE; ACTION POTENTIAL; AMINO ACID TRANSPORT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN HYPOXIA; BRAIN ISCHEMIA; BRAIN SLICE; CALCIUM TRANSPORT; CELL MEMBRANE DEPOLARIZATION; CELL SWELLING; CHLORIDE TRANSPORT; EXOCYTOSIS; HIPPOCAMPUS; HYPERPOLARIZATION; NERVE CELL; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; RECEPTOR BLOCKING;

ACTION POTENTIALS; ANIMALS; BETA-ALANINE; BRAIN ISCHEMIA; CALCIUM; CARRIER PROTEINS; CELL SIZE; EXCITATORY AMINO ACID ANTAGONISTS; EXOCYTOSIS; GABA AGENTS; GABA ANTAGONISTS; GABA PLASMA MEMBRANE TRANSPORT PROTEINS; GAMMA-AMINOBUTYRIC ACID; HIPPOCAMPUS; MEMBRANE PROTEINS; MEMBRANE TRANSPORT MODULATORS; MEMBRANE TRANSPORT PROTEINS; NEURONS; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 1942489741     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5539-03.2004     Document Type: Article

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